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  • Roche announced that in the large pivotal Phase II study, BIRCH, the investigational cancer immunotherapy atezolizumab (MPDL3280A; anti-PDL1) met its primary endpoint and shrank tumours (objective response rate; ORR) in people with locally advanced or metastatic non-small cell lung cancer (NSCLC) whose disease expressed PD-L1 (Programmed Death Ligand-1). The study showed the amount of PD-L1 expressed by a person’s cancer correlated with their response to the medicine. Adverse events were consistent with what has been previously observed for atezolizumab.

  • Researchers found that a new combination therapy was highly effective at treating patients with melanoma, which is known as the most serious type of skin cancer. The findings were published online in the Journal of the American Academy of Dermatology.

  • Nearly 30 per cent of all liver for transplantation is rejected because the donors have 'fatty livers', a disease which is likely to increase in future, the government said. Minister of State for Health Shripad Naik said that the prevalence of non-alcoholic fatty liver disease (NAFLD) is considered to be a known cause of rejection for liver transplantation because of accumulation of fat in the liver.

  • A survey has found that over 11 per cent people in Delhi are suffering from Asthma and Rhinits, the government today said while acknowledging that air pollution is an "aggravating" factor for respiratory and cardiovascular diseases. "As per a survey conducted by Vallabbhai Patel Chest Institute Delhi in 2006, which covered 5,900 adults belonging to urban, rural and slum population in Delhi, 11.69 per cent were found to be suffering from Rhinits and 11.03 per cent from Asthma," Health Minister J P Nadda informed the Lok °Sabha.

  • (NewsVoir); India’s leading health app, 1mg has announced the commencement of "Jaankari Hai To Jaan Hai", an awareness campaign aimed at informing consumers of cheaper alternatives when it comes to cancer medication. The company kick started this ambitious campaign on the occasion of Youth Awareness Day organised in New Delhi by Yoddhas, a prominent NGO that helps cancer patients.

  • A study by Graham Knott at EPFL has successfully used an innovative method, called 'cryofixation', to prevent brain shrinkage during the preparation for electron microscopy. To study the fine structure of the brain, including its connections between neurons, the synapses, scientists must use electron microscopes. However, the tissue must first be fixed to prepare it for this high magnification imaging method. This process causes the brain to shrink; as a result, microscope images can be distorted, e.g. showing neurons to be much closer than they actually are. Scientists have now solved the problem by using a technique that rapidly freezes the brain, preserving its true structure.

  • The study found Restoring testosterone in older men to normal level through gels, patches, or injections may lower their risk of heart attack, stroke, or death from any cause. The study appeared online in the European Heart Journal
    Rajat Barua, assistant professor of medicine at the University of Kansas in the US, said, "It is the first study to demonstrate that significant benefit is observed only if the dose is adequate to normalize the total testosterone levels. Patients who failed to achieve the therapeutic range after testosterone replacement therapy did not see a reduction in (heart attack) or stroke and had significantly less benefit on mortality."

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