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  • Leading health experts from around the world have been meeting at the World Health Organization’s Geneva headquarters to assess the current level of knowledge about the new COVID-19 disease, identify gaps and work together to accelerate and fund priority research needed to help stop this outbreak and prepare for any future outbreaks.

  • Following a review of the risk of meningioma (a rare tumour of the membranes covering the brain and spinal cord) in patients taking cyproterone, EMA’s safety committee (PRAC) has recommended that medicines containing 10 mg or more of cyproterone should only be used for hirsutism (excessive hair growth), androgenic alopecia (hair loss), acne and seborrhoea (excessively oily skin) once other treatment options, including treatment with lower doses, have failed.

  • Less than one in four adolescent men who have sex with men (AMSM) ever get tested for HIV, research funded by the National Institute on Minority Health and Health Disparities (NIMHD), part of the National Institutes of Health, has reported. The study, led by Brian Mustanski, Ph.D., of Northwestern University, Chicago, IL, appeared today in the journal Pediatrics.

  • In September 2018, the National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH, issued its Strategic Plan for Tuberculosis Research, which outlined research priorities to reduce and ultimately end the burden of tuberculosis (TB). TB is a bacterial disease that has claimed the lives of more than a billion people in the past two centuries. Now, a new “Perspective” in The Journal of Infectious Diseases by NIAID Director Anthony S. Fauci, M.D., and other Institute officials summarizes recent progress in improved TB diagnostics, therapeutic regimens and prevention approaches that made 2019 a “banner year” for TB research.

  • Here glioblastoma cells from a human brain are growing. Addition of the Ebola-VSV oncolytic virus results in tumor infection and cell death, seen here as black cells. Over time the infection spreads to other glioblastoma cells.

    Glioblastomas are relentless, hard-to-treat, and often lethal brain tumors. Yale scientists have enlisted a most unlikely ally in efforts to treat this form of cancer — elements of the Ebola virus.

  • The Department of Biotechnology’s Biotech Consortium India Limited (BCIL) is looking for an industrial partner for commercialization of a technology for producing a Bivalent Outer Membrane Vesicles (OMV) vaccine against typhoid. Typhoid fever usually occurs in children aged between 5–15 years.

  • The immune system in the body has an important component called the `complement system’. This is involved in immune surveillance. It is important that it is regulated properly. Otherwise, it can damage the cells of the host’s body itself. This problem is linked to several diseases, including Alzheimer’s, stroke, age-related macular degeneration, asthma, rheumatoid arthritis and cancer.

  • The first clinical trial specifically designed to test the safety of the monthly dapivirine vaginal ring in pregnant women has begun in southern and eastern Africa. The National Institutes of Health-funded study also will test the safety of a daily oral antiviral tablet for HIV pre-exposure prophylaxis (PrEP) in pregnant women and will assess how much they accept and use these two HIV prevention tools. The study will complement an ongoing NIH-funded trial of PrEP in adolescents and young women during pregnancy and the first six months after birth. PrEP is available in some countries and is being rolled out in others, while the dapivirine ring is under regulatory review by the European Medicines Agency for potential use in sub-Saharan Africa.

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