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  • UW researchers find previously unknown links between microbial bile acids and the risk of colon cancer
    18 December 2024

    UW researchers find previously unknown links between microbial bile acids and the risk of colon cancer

    In many ways, that relationship revolves around a specific protein called the farnesoid X receptor, or FXR, which helps maintain a healthy gut through its intimate relationship with bile acids. FXR controls the production of bile acids in the liver, but it also responds in different ways to the presence of various bile acids that microbes have modified.  

  • 18 December 2024
    Unlocking the Brain : Peptide-Guided Nanoparticles Deliver mRNA to Neurons
    Penn Engineers have modified lipid nanoparticles the revolutionary technology behind the COVID-19 mRNA vaccines to not only cross the blood-brain barrier but also to target specific types of cells, including neurons. This breakthrough marks a significant step toward potential next-generation treatments for neurological diseases like Alzheimer’s and Parkinsons.
  • 16 December 2024
    Activating the hidden pharmaceutical potential of bacteria

    Researchers develop a new genetic method for the production of new active ingredients in bacteria

  • 16 December 2024
    Researchers describe a potential target to address a severe heart disease in diabetic patients
    Some patients with diabetes develop a serious condition known as diabetic cardiomyopathy, which is slow and cannot be directly attributed to hypertension or other cardiovascular disorders. This often under-diagnosed heart function impairment is one of the leading causes of death in diabetic patients and it affects both type 1 and type 2 diabetes. There is no current specific drug treatment or clinical protocol approved to address this disease.
  • 16 December 2024
    A low omega-6, omega-3 rich diet and fish oil may slow prostate cancer growth : study finds

    A new study led by UCLA Health Jonsson Comprehensive Cancer Center investigators offers new evidence that dietary changes may help reduce cancer cell growth in patients undergoing active surveillance, a treatment approach that involves regular monitoring of the cancer without immediate intervention.

  • 13 December 2024
    Lynparza demonstrated clinically meaningful prolonged survival benefit in early breast cancer in OlympiA Phase III trial
    Updated results from the OlympiA Phase III trial showed AstraZeneca and MSDs Lynparza olaparib demonstrated sustained, clinically meaningful improvements in overall survival , invasive disease-free survival IDFS and distant disease-free survival DDFS at six years for patients with germline BRCA-mutated gBRCAm HER2-negative high-risk early breast cancer.
  • 13 December 2024
    IBRANCE® in combination with Standard-of-Care therapies extends survival by over 15 months
    Pfizer Inc. and Alliance Foundation Trials, LLC announced results from the Phase 3 PATINA trial demonstrating that the addition of IBRANCE palbociclib to current standard-of-care first-line maintenance therapy following induction chemotherapy resulted in statistically significant and clinically meaningful improvement in progression-free survival by investigator assessment in patients with hormone receptor-positive
  • 13 December 2024
    Antidepressants may act in gut to reduce depression and anxiety

    Most of us have experienced the effects of moods and emotions on our gastrointestinal tract, from “butterflies” in the stomach caused by nervousness to a loss of appetite when we’re feeling blue.

  • 13 December 2024
    A new class of antivirals could help prevent future pandemics
    The arrival of Paxlovid in December 2021 marked another turning point in the COVID-19 pandemic—an effective antiviral that has since successfully treated millions. But like many antivirals before it, scientists know that at some point, Paxlovid is likely to lose some efficacy due to drug resistance. Researchers working to stay ahead of such emerging threats have now identified a wholly new way to treat SARS-CoV-2 infections—work that may have even broader implications.
  • 12 December 2024
    Cipla receives approval for distribution and marketing of inhaled insulin in India
    Cipla Limited announced that it has obtained regulatory approval from Central Drugs Standard Control Organisation for the exclusive distribution and marketing of Afrezza insulin human Inhalation Powder in India. Afrezza, a product created and manufactured by MannKind Corporation
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