Pharma News

Cambridge scientists have shown that it may be possible to spot signs of brain impairment in patients as early as nine years before they receive a diagnosis for one of a number of dementia-related diseases.

In research published today in Alzheimer's & Dementia: The Journal of the Alzheimer's Association, the team analysed data from the UK Biobank and found impairment in several areas, such as problem solving and number recall, across a range of conditions.

Mobile health technology to detect atrial fibrillation generates a high rate of false positives and inconclusive results in some patients with certain cardiac conditions, investigators report in the Canadian Journal of Cardiology.

A research team comprised of members from the Department of Pharmacology and Pharmacy, School of Public Health, Department of Family Medicine and Primary Care, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed), and Laboratory of Data Discovery for Health (D²4H) have conducted one of the first real-world studies to explore the inpatient use of oral antivirals during a pandemic wave dominated by the SARS-CoV-2 omicron variant.

A study group at MedUni Vienna has identified a regulatory loop controlled by leptin, by which this adipocyte-derived hormone regulates hepatic lipid metabolism via the autonomic nervous system. The study provides evidence that this adipose tissue-brain-liver axis, previously identified in animal models, also exists in humans and is opening up new approaches for treating metabolic diseases such as fatty liver disease.

Subject Expert committee of CDSCO recommends for grant of permission to import and market Delamanid Dispersible Tablets 25mg against pulmonary multi drug resistant tuberculosis (MDR-TB) in adults, adolescents, children and infants.

Indian Immunologicals Limited (IIL) announced that the company will invest about Rs 700 Crores to set up a new animal vaccine manufacturing facility in Genome Valley, Hyderabad.

The IIL, a subsidiary of the National Dairy Development Board (NDDB), is already one of the world’s largest FMD vaccine manufacturers. It is also the leading vaccine supplier to the Government of India’s National Animal Disease Control Programme (NADCP).

Nanoscope Therapeutics Inc., a clinical-stage biotechnology company developing gene therapies for retinal degenerative diseases, today announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track Designation (FTD) to MCO-010, an ambient-light activatable Multi-Characteristic Opsin (MCO) optogenetic monotherapy to restore vision in blind patients, for the treatment of retinitis pigmentosa (RP) via intravitreal injection.

Panacea Biotec, one of India's leading biotechnology companies, has received long-term supply awards worth USD 127.30 million (around INR 1,040 Crore) from UNICEF and Pan American Health Organization (PAHO) for supply of its WHO pre-qualified fully liquid Pentavalent vaccine, Easyfive-TT'" (DTwP-HepB-Hib).

Paediatric encephalopathies of genetic origin cause severe motor and intellectual disabilities from birth. One of these diseases, first identified in 2013, is caused by mutations in the GNAO1 gene. In order to understand the finer details of the resulting disturbances, scientists from the University of Geneva (UNIGE) conducted atomic, molecular and cellular analyses. They discovered that a mutation in GNAO1 leads to the replacement of one amino acid by another in protein sequence.