• 29 December 2016

    PREPARATION AND IN-VITRO EVALUATION OF DICLOFENAC SODIUM TRANSDERMAL PATCHES

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    ABOUT AUHTOR
    SUSMITA DAS*
    Department of Pharmaceutical Technology, 
    Jadavpur University,
    West Bengal, India
    *sdas53662@gmail.com

    ABSTRACT:
    Objectives: The aim of the present study was to develop transdermal matrix patches with a fixed ratios of polyvinylpyrrolidone (PVP) and ethylcellulose (EC), containing the drug diclofenac sodium and to perform the physicochemical, in vitro relese pattern evaluation of the prepared patches. The prospective objective was the demonstration that the system provides the delivery of drug at a controlled rate across intact skin to achieve a therapeutically effective drug level for a longer period of time from transdermal patches.
    Methods: In this study, matrix-type transdermal patches containing diclofenac sodium were prepared using different ratio of polyvinylpyrrolidone (PVP) and ethylcellulose (EC) by solvent evaporation technique. The drug matrix film of PVP and EC was casted on a polyvinylalcohol backing membrane. All the prepared formulations were subjected to physical studies (moisture content, moisture uptake, and flatness), and in-vitro release kinetics and permeation studies were performed across cadaver skin using a modified diffusion cell.
    Results and conclusion: Variations in drug release profiles among the formulations studied were observed. From the formulated patches FA 1, containing PVP/EC in ratio of 1:3 shows sustained release action with 38% release after 24 h and 10 µg of drug permeation accross 1 cm2 of patch area. Hence, it can be reasonably concluded that diclofenac sodium can be formulated into the transdermal matrix type patches to sustain its release characteristics for manufacturing transdermal patches of diclofenac sodium

  • 15 December 2016
    Vacancy for Research Chemist at TCG Lifesciences

    TCG Lifesciences Private Limited (formerly "Chembiotek Research International") is a leading contract research services company in the area of early drug discovery and development. We started our operations in the year 2001 in India; currently we have our presence in United States, Europe, Japan and Australia. We have a strong talent pool of 800+ trained scientists, drawn from the best national and international institutes and industry. Our services span from specific solutions to integrated discovery projects across multiple therapeutic areas with focus on Central Nervous System (CNS), Inflammation & Pain, Metabolic Disorders and Infectious Diseases.

    Post : Research Chemist/Senior Research Chemist

  • 14 December 2016
    Jadavpur University invites applications for Guest Faculties

    Jadavpur University is to trace a part of India’s freedom movement, at least from the Swadeshi Movement onwards. It was 1905 -1906. Bengal stood divided. The times were feverish.The hegemony of the British establishment had to be challenged. Education had to play a new role in this changed scenario. It had to become a new form of resistance through which the emergent nationalist spirit could be propagated.

    The University invites applications from Indian Nationals in the prescribed form for Guest Faculties to teach the subjects mentioned for each department in the Second Semester of the (2016-2017) academic session in various Departments of Faculty of Engineering & Technology.

  • 7 December 2016
    Recruitment for M.Pharm, B.Pharm, D.Pharm as Pharmacist at KMC | 80 posts

    KMC invites Applications are invited for engagement of 80(eighty) Pharmacists on contractual basis as mentioned below:

    Post : Pharmacist

  • The Indian Pharmaceutical Association (IPA) strongly opposes the ideas which arise through some recent news indicates that there have been discussion regarding enabling the unqualified persons to be "pharmacists" by initiating some training courses. IPA firmly stated that medical stores/pharmacies should be run only in presence and under supervision of qualified, registered pharmacists.

  • 30 November 2016
    PharmaTutor Magazine - December 2016 is released | Subscribe today

  • 25 November 2016
    Walk in for Research Associate in IACS

    The Indian Association for the Cultivation of Science (IACS), founded on July 29, 1876 by Dr Mahendra Lal Sircar, is an autonomous Institute. It is the oldest research institute in India. The institute is devoted to the pursuit of fundamental  research in the frontier areas of  Physics, Chemistry, Biology, Energy, Polymer and Materials. In each field, IACS nurtures young and innovative research fellows in their doctoral programs.

    Post: Research Associate-I

  • 20 November 2016
    Recruitment for M.Pharm, M.Sc at Jadavpur University - 6 posts | walk in jobs

    To trace the history of Jadavpur University is to trace a part of India’s freedom movement, at least from the Swadeshi Movement onwards. It was 1905 -1906. Bengal stood divided. The times were feverish.The hegemony of the British establishment had to be challenged. Education had to play a new role in this changed scenario. It had to become a new form of resistance through which the emergent nationalist spirit could be propagated. With this in mind the National Council of Education (NCE) came into being

  • 19 November 2016
    Job in research as JRF at Jadavpur University | M.Pharm

    To trace the history of Jadavpur University is to trace a part of India’s freedom movement, at least from the Swadeshi Movement onwards. It was 1905 -1906. Bengal stood divided. The times were feverish.The hegemony of the British establishment had to be challenged. Education had to play a new role in this changed scenario. It had to become a new form of resistance through which the emergent nationalist spirit could be propagated. With this in mind the National Council of Education (NCE) came into being.

    Post: Junior Research Fellow

  • 1 November 2016
    PharmaTutor Magazine - November 2016 is released | Subscribe today

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