Hyderabad

i3 is a full-service Clinical Research Organization (CRO) focused on five therapeutic areas: Oncology; Cardiology; The Central Nervous System; Respiratory and Infectious Diseases; and Endocrinology and Metabolic diseases. Therapeutic specialization drives all aspects of business in this global CRO - from project staffing and talent management to quality initiatives.

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

At i3 Global, We believe in science for the sake of people—in the end, it’s about better patient care.
Because we are a service organization through and through, we’ll build a relationship to suit your specialized needs. Tell us what you need and where in the world you want us to be, and we will deliver.

About Authors:
V. Ravi Chandra
Research Associate
Parexel
B.Pharmacy from Priyadarshini College of pharmacy,
Osmania University,
Hyderabad, AP, INDIA

Abstract:
Huntington's disease is an intricate illness. It is a neurodegenerative, insidious disorder-which means it is harmful and fatal but gradually. The onset of the disease is very late to diagnose the disease. Huntington's disease (HD) also called as ‘Huntington’s Chorea’. Chorea means dance in Greek, which is aftereffect of genetically programmed degeneration of brain cells, called neurons, in certain areas of the brain. This degeneration causes uncontrolled movements, loss of intellectual faculties, and emotional disturbance. By choreic movement physically we can diagnose HD. HD is also a familial disease, passed from parent to child through a mutation in the normal gene. Attempts to study early disease are not unique in neurology (e.g., mild cognitive impairment and vascular cognitive impairment), but studying otherwise healthy-appearing individuals who have nearly 99% certainty of manifesting the symptoms of brain disease does provide distinct but valuable information about the true natural history of the disease. A genetic test, coupled with a complete medical history and neurological and laboratory tests, helps physicians diagnose HD. Presymptomic testing is available for individuals who are at risk for carrying the HD gene. HD occurs in about one out of every 10,000 Caucasian individuals. In India, the cases are unknown because of failure of doctors to diagnose HD as they never seen HD in their practice. Approximately 2.5 times more individuals are at risk for the disorder because of the midlife peak in age at onset.

NEEDS PHARMA, We would like to introduce ourselves a WHO - GMP certified manufacturing unit from INDIA willing to turn the milestone in Pharmaceutical era.
We manufacture Tablets, Capsule, Syrups, Suspensions and other formulations and are exporting to various countries across the Globe.

At Apollo Health Street, we have a strong tradition and belief that personal satisfaction comes from playing an integral part in an organization. In short, we believe in empowered associates.

Incorporated in November 1998, Epsilon Pharmaceuticals Private Limited is located at Jedcherla SEZ, near Hyderabad, Andhra Pradesh. With the advantage of location and a team comprising of experienced scientists and qualified professionals, Epsilon has robust infrastructure and broad technological strengths, capable of manufacturing a wide range of steriles in Oncology segment and also prescription drugs for its clients on contract basis.

National Institute of Nutrition (NIN) was founded by Sir Robert McCarrison in the year 1918 as ‘Beri-Beri’ Enquiry Unit in a single room laboratory at the Pasteur Institute, Coonoor, Tamil Nadu. Within a short span of seven years, this unit blossomed into a "Deficiency Disease Enquiry" and later in 1928, emerged as full-fledged "Nutrition Research Laboratories" (NRL) with Dr.

Indian Immunologicals Ltd. (IIL) in 1982 with the objective of making Foot and Mouth Disease (FMD) vaccine available to farmers at an affordable price. The technology for FMD vaccine manufacture was obtained from M/s. Wellcome Foundation Limited, United Kingdom. The plant in Hyderabad today has a capacity to make 80 million trivalent doses of FMD vaccine.