Hyderabad

About Authors:
Mayure.Vijay Kumar*, V. Sravanthi Yadav, C.P.Meher,
Department of pharmaceutical chemistry
Maheshwara College of Pharmacy, Chitkul (V)
Isnapur “X” Road, Patancheru, Hyderabad.
mayurevijaykumar@gmail.com

ABSTRACT:-
β- lactam antibiotics are  the most commonly prescribed drugs. The β- lactam group of antibiotics are a broad class of antibiotics, consisting of all antibiotic agents that contain a β- lactam nucleus in their molecular structures. This includes penicillin derivatives (penams), cephalosporins (cephems), monobactams, and carbapenems. Most of the β- lactam antibiotics work by inhibiting cell wall biosynthesis in the bacterial organisms and are the most widely used group of antibiotics. Bacteria often develop resistance to β- lactam antibiotics by synthesizing that attacks the β- lactam ring. To overcome this resistance, β- lactam antibiotics are often given with β- lactamase inhibitors such as clavulanic acid. Presnted article deals about the structure of various marketed as well as drugs under investigation containing β-lactam nucleus and  their pharmacological activities. The presented article is related wth the various β- lactam derivative with their various pharmacological activities.

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About Authors:
Nareshkumar. G¹*, A.Eashwar rao², Ch.Ganga prasad³.
¹*Center for Pharmaceutical Sciences, IST, JNTU Hyderabad, India,
²Talla Padmavathi College of Pharmacy, Warangal, India,
³National College of Pharmacy, Shimoga, Karnataka, India.
*nareshkumar62@gmail.com

ABSTRACT:
Liquisolid technique is a new and propitious method that can change the dissolution rate of poorly water soluble drugs. According to the new formulation method of liquisolid compacts, liquid medications such as solutions or suspensions of water insoluble drugs in suitable non-volatile liquid vehicles can be converted into acceptably flowing and compressible powders by blending with selected powder excipients. It has been speculated that such systems exhibit enhanced release profiles. In this case, even though the drug is in a solid dosage form, it is held within the powder substrate in solution or, in a solubilized, almost molecularly dispersed state, which contributes to the enhanced drug dissolution properties. Successful liquisolid tablet is a determination of optimal flowable liquid retention.

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