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  • Vacancy for Brand Executive at Biocon

  • Walk in Interview for Manufacturing Operations as Production Technician, Production - Team Leader / Senior Pharmacist/ Pharmacist @ Apotex - Freshers may mail their CVs

    Apotex Inc., founded in 1974, is the largest Canadian-owned pharmaceutical company. We employ over 6,000 people worldwide in research, development, manufacturing and distribution. We produce more than 300 generic pharmaceuticals in approximately 4000 dosages and formats a nd export to over 115 countries around the globe.

  • Require Fresher as Jr. Executive - production in Biocon

  • Require Business Development Officer in EPIDermizz, a skincare division of Nippon Seiyaku

    EPIDermizz, a skincare division of Nippon Seiyaku Pvt. Ltd. Nippon Seiyaku Pvt. Ltd. is an associate of Nippon Seiyaku co. Ltd., Japan which have been started its operation in Indian Market in 2001. Having robust brand NUTRIFACTS, Nippon is one of the most admired companies in pediatric fraternity. It has the history of pioneering in the area of nutrition by launching molecules like Methylcobalamine, Benfothiamine and Co Enzyme Q10 first time in India.

  • Openings for Territory Managers in Wockhardt - south zone

    Wockhardt today, is distinguished by a strong and growing presence in the world's leading markets, with more than 65% of its revenue oming from Europe and the United States. Wockhardt's market presence covers formulations, biopharmaceuticals, nutrition products, vaccines and active pharmaceutical ingredients (APIs).

  • Career opportunity as Associate Scientific Manager in Biocon

  • Job as Pharmacist in Manipal Hospitals

  • Career in AstraZeneca as Head, R&D Informatics, India

  • Opportunity to make career in Scientific Writing at Indegene

    Indegene's scientific and competitive intelligence services lend actionable insights to clients to support their strategic decision making. We provide scientific, clinical, and competitive insights to help align the business development, licensing, clinical development, and marketing activities of our clients to current and future market needs.

  • ENHANCEMENT OF DISSOLUTION OF POORLY WATER SOLUBLE DRUG USING SUPER DISINTEGRANTS BY KNEADING METHOD

    About Authors:
    YASWANTH ALLAMNENI1*, PAVAN POTTURI1, RAJKUMAR NULU2, RAVADA RAMESH3, P DAYANANDA CHARY1, ARUN KALEKAR1.
    1Research and Development Department, Natco Pharma Limited, Kothur, Mahaboobnagar,Andhra Pradesh, India-509228.
    2Research and Development Department, Aurobindo Pharma Ltd., Hyderabad, Andhra Pradesh, India.
    3HOD, Dept. of Pharmaceutics, Dr. H.L.T. College of pharmacy, Kengal, Channapatna, Banglore(R).

    *yaswanthallamneni@gmail.com

    ABSTRACT
    The aim of this study was to investigate the influence of superdisintegrants on the dissolution properties of a poorly water-soluble drug from complexes prepared by kneading method. Ketoprofen was employed as a model drug. Solid dispersions prepared by kneading method exhibited higher dissolution rate and DE30 values in each case. Ketoprofen tablets were prepared by direct compression technique using microcrystalline cellulose as a directly compressible vehicle. The formulated tablets were evaluated by different In Process Quality Control tests, content uniformity and in vitro drug release study. The FTIR spectra’s study revealed that there were no interaction between polymers and drug. All the tablets formulated employing solid dispersions in superdisintegrants gave rapid and higher dissolution of Ketoprofen when compared to that of Ketoprofen plain tablets. Ketoprofen dissolution from all the tablets followed first order kinetic with correlation coefficient ‘r’ above 0.9470. All dissolution parameters (k1, DE30 and T30) indicated rapid and higher dissolution of Ketoprofen from tablets formulated employing its solid dispersions in superdisintegrants when compared to plain tablets.

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