MOLECULES INVOLVED IN REGULATION OF STEM CELL DIFFERENTITIATION
Cell adeshive molecule E_cadhedrin which replaces oct 4signalling molecule there by converting normal somatic cell into pluripotent

About Authors:
RAVISANKAR.M*¹, SUBASINI.U², ANAND THANGADHURAI.S³, KARTHIKEYAN.S⁴, CHANDRA SEKAR.E.^5
1.Swamy Vivekanandha College of pharmacy, dept of pharmaceutical analysis. Thiruchengode
^2.Swamy Vivekanandha College of pharmacy, dept of pharmacognosy. Thiruchengode
^3.Swamy Vivekanandha College of pharmacy, dept of pharmaceutical analysis. Thiruchengode
^4.Kausikh therapeutics and private limited.chennai
^5.Swamy Vivekanandha College of pharmacy, dept of pharmaceutical analysis. Thiruchengode

ABSTRACT
An isocratic reverse phase high performance liquid chromatographic method for estimation of montelukast sodium and levocetirizine in bulk dosage and in marketed formulations has been devised and validated. The chromatographic separation achieved on shodex c18-4E column (5µm, 250 mm x 4.6 mm) and  acetonitrile: methanol: ammonium acetate buffer (PH- 5.5) in the ratio of 25:55:20 v/v. The flow rate was 1.0 ml/min and the UV detection was identified at 225nm.The retention times for montelukast sodium and levocetirizine was found to be 5.15 min and 3.12 min respectively. The linearity of montelukast sodium and levocetirizine is 10 -50µg/ml with the correlation co efficient 0.99 respectively. The validation parameters such as accuracy, precision, LOD, LOQ, Robustness, ruggedness were performed as per ICH guidelines. This method can be used for routine analysis of montelukast sodium and levocetirizine in bulk and marketed dosage forms.

Kemwell Pvt Ltd., established in the year 1972 at Bangalore, Specializes in contract manufacturing for pharmaceutical formulations for various reputed multinations in India. For its expansion plans is looking for yound dynamic personnel.

Post: QC - Executive

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Forrester Research, Inc. (Nasdaq: FORR) is an independent research company that provides pragmatic and forward-thinking advice to global leaders in business and technology. Forrester works with professionals in 19 key roles at major companies providing proprietary research, customer insight, consulting, events, and peer-to-peer executive programs. For more than 28 years, Forrester has been making IT, marketing, and technology industry leaders successful every day.

United Biotech has been a trend setter of new standards and is among the fastest growing companies in the Indian pharmaceutical Industry. In a span of 12 years it has established an enviable reputation and track record for adopting latest manufacturing technologies, introducing world-class quality of products, ground breaking Research & Development efforts in association with its foreign counterparts and for setting new standards of customer service.

Recruitment applications are invited On-line through the proforma Application to be made available on WEBSITE (apspsc.gov.in) in from 22/02/2012 to 22/03/2012 (Note: 20/03/2012 is the last date for payment of fee) for recruitment to the post of Drug Inspector in A.P. Drugs Control Administration Service.

Deenanath Mangeshkar Hospital and Research Centre was established by Jnana Prabodhini Medical Trust. It is located at the prime location in Pune, Maharashtra. It has beds and Intensive Care Units (ICU) for general, cardiac, neonatal, pediatric, and obstetric. It also provides continuous patient monitoring by central monitoring system, central medical gas pipeline network for oxygen, nitrous, air and vacuum and all types of ventilators to assist respiration.

NEXTUS SOLUTIONS is a professionally managed organization engaged in offering highly acclaimed consulting, Training and Placement. With our in- depth expertise and rich experience in the field of domestic as well as international level, we have been serving aspiring candidatesand organizations in the most professional way.

NEXTUS SOLUTIONS is a professionally managed organization engaged in offering highly acclaimed consulting, Training and Placement. With our in- depth expertise and rich experience in the field of domestic as well as international level, we have been serving aspiring candidatesand organizations in the most professional way.

About Authors:
S Hamza*¹, Dr Tanveer Aalam², Dr Asma^3
1*  Assistant Professor, Department of Pharmacology,
Shree M V Shah Pharmacy college,
Gajan, Modasa: 383315, Gujarat.
² Department of Emergency Medicine,
Apollo hospitals International Ltd,
Bhat GIDC estate,  Gandhinagar: 382428, Gujarat.
³ Medical Officer, Civil Hospital,
Ahmadabad: 380 002. Gujarat, India

ABSTRACT:
India suffers from the highest number of deaths - around 1,05,000 in absolute terms annually- due to road accidents in the world owing to poor infrastructure and dangerous driving habits according to the World Health Organisation¹. Calling road fatalities an "epidemic" that will become the world's fifth biggest killer by 2030². It is said that 90% of deaths on the world's roads occur in low and middle-income countries (21.5 and 19.5 per lakh of population, respectively) though they have just 48% of all registered vehicles.

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With a pedigree from the Personal Care and Pharma industries, VSCL's management brings with it vast product and customer experience. Beyond the leaders, each of our employees have been culturally sensitized to the special quality needs required by our industry, and fully support all our quality initiatives.

Elder Pharmaceuticals is a Mumbai based pharmaceutical manufacturing & marketing organisation. By virtue of its strategic alliances, synergetic acquisitions globally accredited manufacturing facilities & above all an extensive marketing & distribution network, Elder Pharma is one of the fastest growing pharma companies in India.

SIRO Clinpharm is one of the leading Global Clinical Research Organizations (CROs), offering full scope services conducting clinical trials in the Pharmaceutical, Biotechnology and Medical Devices sectors in compliance with International Standards. We are headquartered in India having global presence in USA, Israel and in Europe at Germany, Czech Republic, Greece, Estonia, Romania, Spain and France.

National Institute of Nutrition (NIN) was founded by Sir Robert McCarrison in the year 1918 as ‘Beri-Beri’ Enquiry Unit in a single room laboratory at the Pasteur Institute, Coonoor, Tamil Nadu. Within a short span of seven years, this unit blossomed into a "Deficiency Disease Enquiry" and later in 1928, emerged as full-fledged "Nutrition Research Laboratories" (NRL) with Dr.

Canbari Healthcare is delhi based company.

Post: Medical Representative

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About Authors:
Manoj Kumar Jadia^1*, U.L.Narayan^2
1 Department of Pharmaceutical Chemistry, Indira Gandhi Institute of Pharmaceautical Sciences, I.R.C. Village, Bhubaneswar, Dist:Khurda, Odhisa -751015
² Principal, Department of Pharmaceutical Chemistry, Indira Gandhi Institute of Pharmaceautical Sciences, I.R.C. Village,
Bhubaneswar,
Dist:Khurda, Odhisa -751015

Abstract:
Two methods are described for the simultaneous determination of Paracetamol and Chlorzoxazone in binary mixture. The first method was based on UV-spectrophotometric determination of two drugs, using simultaneous equation method. It involves absorbance measurement at 282.5 nm (λmax of Chlorzoxazone) and 248.0 nm (λmax of Paracetamol) in methanol; linearity was obtained in the range of 5 – 25 μg.mL-1 for both the drugs. The second method was based on HPLC separation of the two drugs in reverse phase mode using Promosil C18 column. Linearity was obtained in the concentration range of 100-500 μg.mL-1 for Paracetamol and 50-250 for  the Chlorzoxazone. Both these methods have been successively applied to pharmaceutical formulation and were validated according to ICH guidelines.

Lupin Limited is an innovation led transnational pharmaceutical company producing a wide range of quality, affordable generic and branded formulations and APIs for the developed and developing markets of the world. The Company today has significant market share in key markets in the Cardiovascular, Diabctology, Asthma, Pediatrics, CNS, GI, Anti-Infectives and NSAIDs therapy segments, not to mention global leadership positions in the Anti-TB and Cephalosporins segments.