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Career for Drug Safety Associate at Novo Nordisk

Novo Nordisk is a global healthcare company with 89 years of innovation and leadership in diabetes care. The company also has leading positions within Haemophilia care, growth hormone therapy and hormone replacement therapy. Headquartered in Denmark, Novo Nordisk employs approximately 33,300 employees in 75 countries, and markets its products in more than 190 countries Novo Nordisk’s B shares are listed on NASDAQ OMX Copenhagen (Novo-B).

Post : Drug Safety Associate

Career at Thomson Reuters as Associate

Thomson Reuters is the leading source of intelligent information for the world's businesses and professionals, providing customers with competitive advantage. Intelligent information is a unique synthesis of human intelligence, industry expertise and innovative technology that provides decision-makers with the knowledge to act, enabling them to make better decisions faster. Through its more than 50,000 people across 93 countries, Thomson Reuters delivers this must-have insight to the financial, legal, tax and accounting, scientific, healthcare and media markets, and is powered by the world's most trusted news organization.

Post : Associate

Recruitment for M.Pharm, B.Pharm, M.sc in Quality Control and Quality Assurance at Torrent Pharma | walk in

Torrent Pharma, the flagship company of Torrent Group, is ranked amongst the top pharma companies of India. It is a dominant player in the therapeutic areas of cardiovascular (CV) and central nervous system (CNS) and has achieved significant presence in gastro-intestinal, diabetology, anti-infective and pain management segments. Torrent Pharma has a strong international presence spanning over 70 countries across five continents with over 1200 product registrations. Today, Torrent Pharma, with its state of the art manufacturing and research facilities and a global presence, is all poised to carve a niche foritselfintheinternationalpharmaarena.lt is well set on an exciting growth phase in all directions.

Post : Tech. Asst. / Executive / Asst. Manager

Job for DGM, AGM, Microbiologist at Otsuka Pharmaceutical | M.Pharm, B.Pharm

Otsuka Pharmaceutical India Private Limited (OPI) is a major player in Infusion Business in India and Emerging Markets. We primarily manufacture & market products across multiple markets and therapeutic segments. To keep pace with our growth plans, we require experienced and highly competent team members in following areas for our manufacturing facility at Ahmedabad, Gujarat.

Forretindia looking for Nurse | 35 posts

Forretindia is fasted growing Company.

Post : Registered Nurse - UK

Work as Manager at Biolabs

Pioneers in natural herbal supplements. Innovation driven by research and development. Scientifically proven components and formulations to keep healthy life.

Post : Manager - 02 posts

Career for Pharmacy Graduates to work as Clinical Research Coordinator at NIMS

Applications are invited from suitably qualified and experienced candidates in the prescribed format (to be copied on a plain paper) for the temporary post(s) mentioned below in the research project titled

Post: Clinical Research Coordinator

Job for Post doctoral fellow at IITK | Salary upto 50,000 pm

The history of the IIT system dates back to 1946 when a committee was set up by Hon'ble Sir Jogendra Singh, Member of the Viceroy's Executive Council, Department of Education, Health and Agriculture to consider the setting up of Higher Technical Institutions for post war industrial development in India. The 22 member committee headed by Sri N.R.Sarkar, in its report, recommended the establishment of four Higher Technical Institutions in the Eastern, Western, Northern and Southern regions, possibly on the lines of the Massachusetts Institute of Technology, USA, with a number of secondary institutions affiliated to it.

Post : Post doctoral fellow

Applications are invited for Technical Assistant at IBSD | Government Job

Applications are invited from deserving and suitable candidates for the post of Project Technical Assistant for IBSD, Sikkim Centre, Gangtok on contractual basis for the project entitled “Establishment of Culture Collection Centre in North East Region of India” under Department of Biotechnology (DBT), Govt. of India.

Post : Project Technical Assistant

Recruitment for M.Pharm, B.Pharm in Strategy & Project Management at Bliss GVS

Bliss GVS is a fast-growing Pharmaceutical Company with a proven track record of developing, manufacturing and marketing high quality pharmaceutical formulations at affordable prices for the global market. We are a public limited company listed on India’s National Stock Exchange and Bombay Stock Exchange with more than three decades of industry expertise.

Post : Strategy & Project Management

Vacancy for Junior Research Scientist at Piramal

Piramal Life Sciences Limited (PLSL) is an independent research-driven drug company that was recently demerged from Piramal Healthcare Limited (Formerly known as Nicholas Piramal India Limited). PLSL was formerly the NCE R&D division of NPIL. PLSL has state-of-the-art R&D laboratories built over 200,000 square-feet of space in Mumbai, India and over 300 scientists engaged in drug discovery and development.

Post : Junior Research Scientist

Walk in interview for QC and Validation at Micro Labs Limited | B.Pharm, M.Sc

Micro Labs Limited is a multi-faceted healthcare organization with a proficient marketing team, state-of-the-art manufacturing facilities and R&D centres that are at par with international standards. All this, robustly backed by a strong distribution network and path-breaking research work has placed us amongst India’s fast growing transnational healthcare organizations.

Post : Officer / Executive for QC and Validation

Recruitment for Consultant (6 posts) under MOHFW - Government of India

National Institute of Biologicals an autonomous Institution under the Ministry of Health & Family Welfare (MOHFW)-Government of India is a premier Scientific Organization and a Centre of Excellence to ensure quality of biologicals and vaccines in the country. The institute responsibly assures and reviews the quality of number of  Biological products available through domestic manufacturers or imports. The operations are carried out in the state of the art Facility of the Institute and in close coordination with Government of India regulatory authorities as Office of Drug Controller of India, Indian Pharmacopeia's Commission.

Post : Consultant

Kidney Research UK PhD Studentship in Immuno-nephrology at Newcastle University

Newcastle University, we have always focused on academic excellence and the impact of our academic work. Today, these long-held ideals are more relevant than ever. They define our vision for the University – the kind of university we wish to be.

Required for Regional Manager at Medtronic

Covidien and Medtronic are committed to improving the lives of patients through ground-breaking medical technologies. By bringing our companies together, we are able to expedite our ability to create the meaningful innovations and therapies that fuel our mission to improve patients’ lives. This partnership will create new opportunities for skilled, ambitious people to change the way we work, and ultimately deliver better health for more people.

Post : Regional Sales Manager/ District Manager, Reg/Ctry

STUDY OF IN-VITRO BIOTRANSFORMATION OF PRODRUGS OF ESTER AND AMIDE LINKAGES OF IBUPROFEN, DICLOFENAC SODIUM AND PARACETAMOL IN ACIDIC AND ALKALINE MEDIUM

{ DOWNLOAD AS PDF }

ABOUT AUTHOR
Dhrubo Jyoti Sen
Department of Pharmaceutical Chemistry,
Shri Sarvajanik Pharmacy College,
Mehsana, Gujarat, India
dhrubosen69@yahoo.com

ABSTRACT: Our goal is to perform in-vitro biotransformation of Prodrugs of ibuprofen+paracetamol, diclofenac sodium+paracetamol and ibuprofen+diclofenac sodium by acidic and alkaline hydrolysis of both ester (–COO–) and amide (–CONH–) linkages into free drugs and chromatographically separation of their Rt in HPLC. Since both ester (–COO–) and amide (–CONH–) linkages are susceptible for hydrolysis in both acidic pH (gastric pH) and basic pH (intestinal pH) to produce parent drug ibuprofen, diclofenac and paracetamol by biotransformation in in-vivo; so it will be implemented as a Prodrug which can show prolong action on pain and fever after getting release into free parent drug by biotransformation. The HPLC (High Performance Liquid Chromatography) study reports the retention time (Rt) and release kinetics of three Prodrugs by taking HPLC degradation datas of three samples of Prodrugs and individual HPLC datas of parent drugs separately to compare the Rt value of release of three drugs from Prodrugs in both acidic and alkaline pH. Prodrug–A (logP=4.56) releases Ibuprofen & Paracetamol, Prodrug–B (logP=4.90) releases Diclofenac & Paracetamol and Prodrug–C (logP=6.13) releases Ibuprofen & Diclofenac. This is a comparison study of drug release in in-vitro gastric as well as intestinal pH focusing on in-vivo biotransformation.  Keywords: Prodrug-A/Prodrug-B/Prodrug-C, Ibuprofen, Paracetamol, Diclofenac sodium, Molecular weight, logP, UV λmax, IR, Mobile phase, TLC-Rf value, HPLC-Rt value, LOD, LOC

Career for Pharmacist and Senior Pharmacist (10 posts) in 1MG Technologies Pvt Ltd

We want you to understand the medicines that you take and that you give your loved ones. Buying medicines may require you to try 5 medical stores which are miles apart. We want you to be able to do it with a click. Medicines can be expensive. We want you to know about medicines which have the same composition as prescribed by your doctor but can be considerably cheaper. We want you to be in charge of your medical care.

Post: Pharmacist / Sr. Pharmacist (10 posts)

Recruitment for M.Pharm, M.Sc at Guru Jambheshwar University

The Guru Jambheshwar University of Science & Technology, Hisar, was established on October 20,1995 by an Act of the Legislature of the State of Haryana with the objectives 'to facilitate and promote studies and research in emerging areas of higher education with focus on new frontiers of technology, pharmacy, environmental studies, non-conventional energy sources and management studies and also to achieve excellence in these and connected fields'. It was formally inaugurated on November 1, 1995. It is named after Guru Jambheshwar Ji Maharaj, a saint environmentalist of 15th century. Keeping in view the nature of courses offered at the university and the mandate for which it had been established the name of the university has been changed as Guru Jambheshwar university of Science & Technology.

Post : Junior Research Fellows (06 posts)

Invites Applications for Research Associate at BRNS

Dr. Homi Jehangir Bhabha conceived the Nuclear Program in India. Dr Bhabha established the Tata Institute of Fundamental Research (TIFR) for carrying out nuclear science research in 1945. To intensify the effort to exploit nuclear energy for the benefit of the nation, Dr Bhabha established the Atomic Energy Establishment, Trombay (AEET) in January 1954 for multidisciplinary research program essential for the ambitious nuclear program of India. After the sad demise of Bhabha in 1966, AEET was renamed Bhabha Atomic Research Centre (BARC).

Recruitment Drive in Quality Assurance and Quality Control at Syngene International | M.Pharm, M.Sc

Incorporated in the year 1994, Syngene International is one of India"s premier contract research and manufacturing organizations in providing customized service. Our services encompasses all across discovery chain: early stage discovery, process development, cGMP manufacturing and formulation development both in the small molecule and novel biologics area. Based in Bangalore, Karnataka, the Company is situated in a 90 acre Special Economic Zone with over 100000 sq. mt of built up facilities.

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