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Development and Validation of High Performance Liquid Chromatography method for analysis of Gatifloxacin & its Impurity

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March 2017 ARTICLE LIST >>

PharmaTutor (March - 2017)

 

ISSN: 2347 - 7881
(Volume 5, Issue 3)

 

Received On: 08/11/2016; Accepted On: 22/11/2016; Published On: 01/03/2017

 

AUTHORS:
Narendra M.Petha, J.G.Patil,J.G.Chandorkar
Indofil Industries Ltd, Gujarat
jchandorkar-icc@modi.com

 

 

ABSTRACT:
Gatifloxacin is a antibacterial agent, Rapid, sensitive and selective analytical method is essential for monitoring the different reactions steps involved in process development of Gatifloxacin. A simple isocratic reverse phase High Performance Liquid Chromatographic [HPLC] method was developed for simultaneous separation of different intermediates and other impurities. The method was utilized successfully in analyzing the reaction streams, related substances in final product and for the assay in drug.

 

 

How to cite this article: Petha NM, Patil JG, Chandorkar JG;Development and Validation of High Performance Liquid Chromatography method for analysis of Gatifloxacin & its Impurity; PharmaTutor; 2017; 5(3); 37-41

 

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