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Basics of aging theories and disease related aging-an overview


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February 2017 ARTICLE LIST >>

PharmaTutor (February - 2017)


ISSN: 2347 - 7881
(Volume 5, Issue 2)


Received On: 12/09/2016; Accepted On: 14/12/2016; Published On: 01/02/2017


Abhijit De 1*, Chandan Ghosh1
1 Department of Pharmaceutical Science,
Bengal School of Technology, Hooghly, West bengal, India



ABSTRACT: Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. This deterioration is the primary risk factor for major human pathologies including cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases. In this review, several theories and mechanisms have been put to explain the molecular basis of aging. For example, random damage of the DNA of somatic cell is believed to accumulate with increasing age. Free radicals produced during oxidation of metabolites for energy production also damage DNA and proteins.



How to cite this article: De A, Ghosh C; Basics of aging theories and disease related aging-an overview; PharmaTutor; 2017; 5(2); 16-23