The St. John's Research Institute (SJRI) is a part of the St John's National Academy of Health Sciences, which is run by the CBCI Society for Medical Education. From its inception, St. John's has set before it an ideal of excellence in academic courses as well as service to society as a result of which it has truly become holistic both in its outlook and in its approach to the problems of community health. In 2000, the Academy decided that its commitment to excellence in research required the setting up of an Institute that was dedicated to the pursuit of research and capacity development in St. John's. This vision encompassed improvement of health of the community and patients through research and development of a Center for Excellence in medical research in India.
Post : Project Assistant - RHoVAC Project
Job Summary
RhoC is a small GTPase, which is actively involved in actin cytoskeletal organization in cells. Functionally distinct from other Rho GTPase family members it has been shown to contribute several tumor's progression. Cancer recurrence or non-response and metastasis is largely attributed to cancer stem cells (CSCs). Our previous publications show that RhoC regulates therapy response and stem cell maintenance in cervical cancer. RhoVac (now known as CHOSA Oncology), has developed an immuno-oncologic drug called RV001, a peptide antigen that establishes an immune response which results in anticancer response and attacks metastatic cells. However, it is not known how RhoC is presented on tumor cells to enable recognition by the immune system. This study proposes to evaluate different levels of expression of RhoC in various cells and correlate with the HLA type and expression.
Key Responsibilities :
Literature review, performing experiments, data analysis, report writing, manuscript writing.
Eligibility Criteria :
Preferred Qualifications : M.Sc in Life Sciences
Preferred Language : English
To Apply : E-mail cover letter and curriculum vitae with 3 references (names and email addresses / phone numbers) by on or before 20th May 2026 to pavana.thomas@stjohns.in & cc to hr@sjri.res.in
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