Advertisement for Project Technical Support at Tata Medical Center

The Tata Medical Center (TMC) is a multispecialty institution for tertiary cancer care based in New Town, Kolkata. At TMC, clinical and research activities are integrated to provide state-of-the-art care for patients with cancer. This integration is enabled by the Tata Translational Cancer Research Centre (TTCRC), the research arm of TMC. TTCRC is within a dedicated academic space and spread over 3 floors. At TTCRC, a multidisciplinary team of clinicians, scientists, academics and industry professionals collaborate to develop a systems medicine approach in cancer research. This approach is focussed on developing innovative, indigenous, cost-effective and equitable strategies to improve cancer diagnosis; develop treatments that match disease characteristics and are adapted to treatment response; and, identify prognostic and predictive disease biomarkers.

Post : Project Technical Support-III

Project : Rapid and Affordable Diagnostics for stratifying Childhood Acute Lymphoblastic leukaemia (RADICAL), IIRPIG-2024-01-00028
Funding : Indian Council for Medical Research, New Delhi
Duration : 4 years (2025-2029)
Principal Investigator : Dr. Mayur Parihar
Senior Consultant Cytogenetics, Molecular Pathology and Haemato-Pathology, Tata
Medical Center, Kolkata - 700160
Clinical Scientist, Genomics, Officer-in-charge Tata Translational Cancer Research Centre

Cancer Genomics Laboratory and the Position
In this position, you will be required to work as part of the Cancer Genomics Lab (CGL) at TTCRC. CGL has several ongoing national and international collaborative studies. We have a dedicated laboratory facility equipped with Illumina, Sanger and Nanopore sequencers and is an internationally accredited centre for the minimal residual disease detection in childhood ALL (EuroMRD Consortium). A dedicated informatician supports the data analyses. Our primary focus is to refine the genomic landscape of childhood ALL patients using high-throughput technologies. You will closely work with the Department of Cytogenetics in Tata Medical Center, Tata Medical Biorepository (TiMBR), Clinical Research Unit (CRU) group at TTCRC. You will be given a designated desk and computer for carrying out your work.

Roles and Responsibilities
Your primary responsibility will be to integrate with the existing laboratory workflow and maintain good laboratory practices.
(a) Identifying patients eligible for the study
(b) Check availability of samples from biobank
(c) Isolation and Quality Control of DNA and RNA required for the RADICAL workflow
(d) Active participation in library preparation and optimisation of the high-throughput workflows that includes hands-on experiment
(e) Proper documentation of regular experiments carried out and troubleshooting if required.
(f) Participation in SOP preparation and helping out with preparation of annual reports.
(g) Basic data analysis skills

Minimum required qualifications/experience (ICMR Guidelines)
1. Three Years Graduate in relevant subject/field + three years’ experience OR Post-Graduate in relevant subject/field
2. For Engineering/IT/CS- First Class Four Years Graduate Degree + Three Years’ Experience.

Desired qualifications/experience
(a) M.Sc. (with 1-2 years of experience) in Biological Sciences with expertise in Molecular Biology and Genomics
(b) Expertise in DNA extraction, qPCR, Sanger Sequencing, NGS library preparation and sequencing using Oxford Nanopore Technology (preferable)
(c) Soft skills : MS Office, Excel, Laboratory and clinical data documentation, Data analysis tools using R packages, PRISM, SPSS etc. (preferable)

Necessary qualities
(a) Integrity, motivation, enthusiasm, responsibility and reliability
(b) Focus and commitment in carrying out tasks and duties
(c) Critical analytical and problem-solving skills, capable of independent work
(d) Ability to work effectively as part of a multidisciplinary team

Salary : Rs 28,000 pm + 30% HRA, increment as per ICMR guidelines.

Appointment and reporting : Appointment to the position will initially be for 1 year with scope for renewal in subsequent years subject to satisfactory review of performance through periodic appraisals and availability of funding.
The person would directly report to the group lead/PI of project on a regular basis and update status of the project.

Submission of applications by post or by e-mail to :
Mr Suvasish Mukherjee; Head, Human Resources;
Tata Medical Center; 14 Major Arterial Road (East- West); Newtown, Rajarhat; Kolkata 700 160
e-mail: suvashish.mukherjee@tmckolkata.com

Application Closing Date : 23rd May 2025