About Authors: Anjali Gureja; 4th B.Pharm Student
N jawahar; Lecturer Department of Pharmaceutics
Mihir Trivedi; 4th B.Pharm Student
Anusha K; 4th B.Pharm Student
Prashant Subhashrao Wake; M.Pharm Student
Reference ID: PHARMATUTOR-ART-1072
Patient compliance is necessary for optimum therapeutic outcome and the extent of adverse effects,convenience and cost of the drug determine the success of a medicine In recent years, there has been increasing interest on the use of bioadhesive polymers to control the delivery of biologically active agents systemically or locally The present study includes in the increased interest and use of bioadhesive polymers in bucco adhesive drug delivery system.Which is useful for drugs which are succeptible to extensive gastrointestinal degradation and first pass metabolism. Buccal administration as a method of preventing presystemic metabolism
1. As it provides.highy vascular site 2. Regional variation in permeability to drugs 3. Passive diffusion of unionized drugs 4. Escapes first pass metabolism.
A bioadhesive system plays a major role, due to its potential leads to high demand for buccal drug delivery system.