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Nandu Kayande1*, Pankaj Kushwah2, D.K. Vir3
1HOD Department of Pharmacology
2Department of Pharmacognosy
3Department of Pharmacology
Nimar Institute of Pharmacy, Dhamnod,
Opp.ITI, Maheshwar Road Dhamnod, Dhar. M.P.454552
The objective of present study was to evaluate in vivo anti-diarrheal potential ofCinnamon leaves. Sample was analyzed for quantities estimation of photochemical and anti-diarrheal activity of aqueous leaf extract, at 100, and 200 mg/kg body weight (b.w) was investigated using castor oil induced model. The aqueous leaves extract of Cinnamon leaves (100, and 200 mg/kg body weight) was administered orally to three groups of rats (five animals per group) in order to evaluate the activity of the extract against castor oil-induced diarrhea model in rat. Two other groups received normal saline (5mg/kg) and Loperamide (2mg/kg) as positive control. The effect of the extract on castor oil-induced diarrhea, gastrointestinal transit and intestinal fluid accumulation (enter pooling) was assessed respectively. In this study, the phytochemical analysis of aqueous leaves extract of Cinnamon leaves revealed the presence of alkaloids, terpenoids, flavonoids, saponins, tannins and phenols. At oral doses of 100, and 200 mg/kg body weight, the plant extract showed pronounced significant (p<0.05) antidiarrhoeal activity compared to the control group. No mortality and visible signs of general weakness were observed in the rats following the extract administration of up to a dose of 2000 mg/kg. The results showed that the aqueous leaves extract of Cinnamonleaves has a significant antidiarrhoeal activity which supports its use in traditional herbal medicine practice.
Global Institute of Regulatory Affairs provides Industry Oriented Courses in Regulatory Affairs (RA), Quality Assurance & Quality Control (QA/QC) for Life Science Graduates with Placement Assisstance in Pharma Sector
Global Institute of Regulatory Affairs (GIRA) is a change that will help you begin & grow your career in Pharma Industry. GIRA through its industrial expertise offers quality educational programs in the field of Regulatory Affairs and QA/QC. It offers Full time, Part time and Distance Learning courses; this flexibility ensures prior commitments are taken care of and at the same time skills are added to their CVs.
Certifications: GIRA is an ISO Certified Institute as per the norms of ISO 9001:2008. It is Accredited by Joint Accreditation System of Australia & New Zealand (JAS-ANZ).
Distance Learning Courses Offered by GIRA:
* Post Graduate Program in Regulatory Affairs (PGDRA- 10 months)
* Certificate Course in e-CTD (4 months)
* Certificate Course in QA/QC (6 months)
Note: Fast Track mode also available for the above given courses.
* Completely Online (From Admission to Examination)
* Industry Accepted Course Curriculum & Certificate
* Experienced and Quality Faculty
* Online Examination (Exams from Home)
* Online Interaction (Discussion Forums, GIRA Blog)
* 100 % Placement Assistance & Career Guidance
Candidates Pursuing Courses from GIRA are associated with:
Emcure Pharmaceutical Ltd, Novartis Pharma, Dr Reddys Laboratories Ltd, Wockhardt Pharma, Cipla, Glenmark Pharmaceuticals, Himalaya Company, USV Limited, Mylan Labs, Glaxo Company, Macleods Pharma, Ranbaxy Pharma, Torrent Pharmaceuticals, TCS etc.. etc.. etc..
S.O. Pratap1,2, Ruchi Gaur3, R.Stephan4, J.L bhatt3, C.R. Pillai1, Usha Devi1
1Malaria Research Center, New Delhi
2SR Group of Institutions, Jhansi, UP
3ITM University Gwalior, MP
4Government P.G. College Ariyalur, Tamilnadu, India
The natural products are important source of biologically active compounds having potential for developing a novel malaria drug. Malaria is one of the most important infectious vector born parasitic disease caused by Coccidian protozoan parasite of genus Plasmodium carried out by mosquito, invade red blood cells. Malaria is thousand times more complex than any disease. In the current study, a natural ingredient of herb; Dhatura Inoxia is analyzed, for its anti-malarial activity by preparing crude extract of water and ethanol, analyzed on schizont stage of plasmodial life cycle against two Chloroquine strains: sensitive and resistant of Plasmodium falciparum isolates. The results revealed that IC50 values of crude water extract was recorded as; 71± 1.41µg/ml and 105±7.07 while as the ethanol crude extract produced IC50 concentrates: 52±3.53 µg/ml and 59.5± 70 µg/ml against sensitive and resistant P. f. isolates, respectively. The results showed that this herb plant possess significant antiplasmodial activity in terms of IC50 as recorded in this study.
Carrying forth the Apeejay Stya legacy of over 45 years of excellence in education
School of Pharmaceutical Sciences
Experience the International Edge...
· Established on the academic pattern of the lvy League universities of the USA
· Trans-disciplinary and Liberal Arts approach
· Strong industry linkages to facilitate training & placement
· Truly global campus with students from over 15 countries
Awards & Accolades
· Best Innovation by Private University at World Education Summit 2012
· No.1 in Innovative Teaching Techniques & No. 3 in Most Reputed Faculty as per TOI B-School Ratings 2013 (North Region)
· Mr. Aditya Berlia, Co-Founder & Pro-Chancellor, Apeejay Stya University, received the 'Outstanding Educational Entrepreneur' award at the World Education Congress Global Awards 2013.
· ASU has been conferred the 'CSR Excellence in Education Award 2013' by Competition Success Review (CSR) magazine in recognition of exceptional contribution made by institutions in their respective areas like education, scientific research, etc.
· E-Gov. Campus of Gurgaon District, Haryana (India) by the Ministry of Communications & Information Technology, in collaboration with the United Nations
· Best Engineering Institute in North India at National Education Awards 2013 by ET Now
Northern Coalfields Limited was formed in November 1985 as a subsidiary company of Coal India Limited. Its headquarter is located at Singrauli, Distt. Singrauli (M.P.). Singrauli is connected by road with Varanasi (220 Km ), The nearest railway station is Singrauli located on the Katni-Chopan branch line running parallel to the northern boundary of the Coalfield. The nearest railway station for reaching directly to Delhi is Renukoot that is located on the Garhwa-Chopan rail-line. Nearest (private) airstrip is at Muirpur (60 Km.).
Northern Coalfields Limited, Singrauli; a well known Public Sector Undertaking of Government of India in Coal Sector, invites applications from the citizens of India for the following posts:
Post: Jr.Pharmacist Gr.C
Career in Panacea Biotec for the post of Executive Sales and Market Development | B.Sc., B. Pharma, M.Sc, M. Pharma
Panacea Biotec is a leading research based Health Management Company, with an annual turnover of approx. Rs. 830 Crores. We are engaged in research, development, manufacture & marketing of Vaccines, Bio-Pharmaceuticals and Pharmaceuticals (Rx & OTC) of international quality and Health Services. All Panacea Biotec plants are accredited by international agencies and they follow current Good Manufacturing Practices, as per WHO guidelines.
We offer stimulating work environment & a career that spells growth. In tune with our plans, we require young, aggressive, dynamic, high performing and result oriented professional.
Post: Executive Sales and Market Development
MPOnline project has realized the vision of the government to provide government services at the doorsteps of citizen and businesses. During the relatively short term since its establishment, the benefits of the project have penetrated deep into the urban as well as rural areas, and deliver a very wide spectrum of services.
MP Government, Jail departments direct recruitment of Pharmacist grade -2
Post: Pharmacist Grade -2 (Direct Recruitment)
Jiwaji University requires faculties in Pharmaceutics, Pharmacology, Pharmaceutical Chemistry, Pharmacognosy, Pharmaceutical Analysis - 11 posts
Jiwaji University was established as a teaching and affiliating University on 23rd May 1964, under the provision of M. P. Government Ordinance no. 15 of 1963. Dr. Sarwapalli Radhakrishanan, the then President of India, laid the foundation stone of the University Campus on 11th December 1964
Right from its inception, Jiwaji University started with a status of a residential and an affiliating University. The territorial jurisdiction of the affiliation extends to six districts of Gwalior and Chambal Division, viz., Gwalior, Morena, Bhind, Guna, Shivpuri and Datia. To begin with, the University had a total of 29 affiliated colleges. Those have steadily increased to more than 100 colleges. Till date of 26 Government and 7 non-Government colleges impart teaching up to postgraduate level. Some of the colleges have also developed into recognized research centers.
Application on the prescribed forms available on jiwaji university website are invited from eligible candidates for the following contractual teaching posts in school of studies in pharmaceutical sciences
Post: Teaching Position
Liver is the key organ of the body. It is the largest gland in the body and weighing between 1to 2.3 kg.
It is situated in the upper part of the abdominal cavity. Occupying the greater part of the right hypochondriac region one part of the epigastric region and extending into the left hypochondriac region.
The liver is described as having four lobes. The two most obvious are the large right lobe and the smaller, wedge shaped left lobe. The other two caudate and quadrate lobes are areas on the posterior surface.
At least one article is seen in newspaper on obesity on daily basis; no other disease is searched (and articles are read on) as frequently as obesity. Such is the menace of obesity that even fast food giant McDonald's has put an advice in few of its offices “not to eat too much fast-food”. Obesity is defined as BMI (body mass index) 30kg\m2 or more. A person with a BMI between 25 and 29.9 are considered over weight but not obese. BMI is a simple index of weight-for-height that is commonly used to classify overweight and obesity in humans. It is also defined as a person’s weight in kilograms divided by the square of his height in meters (kg\m2). As per world health organization (WHO), BMI greater than or equal to 25 is overweight and BMI greater than or equal to 30 is obese. Obesity is a foremost health problem not only in developed nations but also in developing countries. It increases the risk of other diseases like diabetes, cardiovascular ailments, fatty liver and some forms of cancer1. Obesity is now so common in various geographies that it is beginning to replace conditions arising from malnutrition and infectious diseases as the most significant contributor to ill health. Obesity is measured using BMI and further evaluated in terms of fat distribution via the waist–hip ratio and total cardiovascular risk factors2. BMI is closely related to both percentage body fat and total body fat3. The global epidemic of obesity results from an amalgamation of such factors as genetic susceptibility, increased availability of high-energy foods and diminished need of physical activity in prevailing situation in modern society. Obesity is no more a cosmetic issue affecting certain individuals, but a pandemic threatening global well being because it exacerbates a large number of health-related problems, both independently and in association with other ailments4,5.