Uttar Pradesh

The Indian Institute of Toxicology Research (IITR), Lucknow, a premier institute under the Council of Scientific and Industrial Research (CSIR) is involved in multidisciplinary R&D programmes of both basic and applied nature across scientific disciplines for economic, environmental and societal benefits for the people of India. IITR, Lucknow engaged in the areas of Environmental Toxicology, Food, drug and chemical toxicology , Systems Toxicology & Health Risk Assessment, Regulatory toxicology, Nanotherapeutics & Nanomaterial Toxicology and also National S&T Missions. IITR has two campuses; the main campus is located at the centre of Lucknow City and the other campus at a distance of approx.

CSIR-Central Drug Research Institute, Lucknow is a premier R&D Institute under the aegis of the Council of Scientific and Industrial Research (CSIR), New Delhi which is an autonomous body under Department of Scientific and Industrial Research, Government of India. The institute is engaged in the development of new drugs and diagnostics in various therapeutic areas like malaria, tuberculosis, filarial, leishmania, cancer, thrombosis, hypertension, dementia, diabetes, lipid disorders, gastric ulcer, osteoporosis, prostatic hyperplasia, etc. supported by very competent team of chemists and biologists.

The National Institute of Pharmaceutical Education and Research (NIPER) has been created as a centre of excellence for higher education, research and development in pharmaceutical sciences. NIPER, Rae Bareli at ITI campus, Rae Bareli under the mentoring Institute of Central Drug Research Institute, Lucknow invites eligible candidates for following positions on purely temporary basis on contract initially for a period of 1 year which can be extended further.

About Authors:
Mohd. Yaqub Khan*, Poonam Gupta, Bipin Bihari, Vinod Kumar Singh, Sanjay Kumar Yadav, Aparna Misra
Saroj Institute of Technology & Management,
Ahimamau P.O. Arjunganj Sultanpur Road, Lucknow  -226002
*khanishaan16@yahoo.com

Abstract
Epidermolysis bullosa(EB) is an inherited connective tissue disease causing blisters in the skin and mucosal membranes, with an incidence of 1/50,000. Its severity ranges from mild to lethal. The skin is extremely fragile: minor mechanical friction or trauma will separate the layers of the skin and form blisters. People with this condition have an increased risk of cancers of the skin, and many will eventually be diagnosed with it as a complication of the chronic damage done to the skin. The skin has three layers; the outermost layer is the epidermis, and the middle layer is the dermis. In individuals with healthy skin, there are protein anchors between the layers that prevent them from moving independently from one another (shearing). In people born with EB, these top skin layers lack the protein anchors that hold them together, and any action that creates friction between them (like rubbing or pressure) will create blisters and painful sores. Sufferers of EB have compared the sores with third-degree burns.  Current clinical research at the University of Minnesota has included a bone marrow transplant to a 2-year-old child who is one of 2 brothers with EB. Sulforaphane, a compound found in broccoli, was found to reduce blistering in a mouse model to the point where affected pups could not be identified visually, when injected into pregnant mice (5 µmol/day = 0.9 mg) and applied topically to newborns (1 µmol/day = 0.2 mg in jojoba oil).

The Reserve Bank of India was established on April 1, 1935 in accordance with the provisions of the Reserve Bank of India Act, 1934.
The Central Office of the Reserve Bank was initially established in Calcutta but was permanently moved to Mumbai in 1937. The Central Office is where the Governor sits and where policies are formulated.
Though originally privately owned, since nationalisation in 1949, the Reserve Bank is fully owned by the Government of India.

HLL Lifecare Limited (formerly Hindustan Latex Limited) India’s leading manufacturers and marketers of Contraceptive, Health Care and Pharma products is a Mini Ratna Company under the Ministry of Health & Family Welfare, a Govt. of India Enterprise, with Seven manufacturing units and marketing offices throughout the country.

The IIMT Group of colleges was founded in the year 1994. Since then the group has grown impressively and achieved exemplary recognition from corporate, academia, and professional circles.
At IIMT we are committed to provide a value driven culture along with creating a professional environment. The IIMT as a group is large and diversified group and imparts knowledge in field of Engineering, Management, Medical Sciences, Hotel Management, Nursing, Education, Law etc. The IIMT group has more than 1330 highly qualified and experienced faculty members in their respective functional areas. IIMT boasts of having more than 20,000 students in various courses in five campuses.

ABOUT AUTHOR:
Vishwa Deepak kumar
Departement of Pharmacy,
IEC group of institution,
Greater Noida (U.P), Pin- 201301
vdkumar.iec@gmail.com

ABSTRACT:
Pharmacovigilance is an important and integral part of clinical research. Pharmacovigilance is “defined as the pharmacological science relating to the detection, assessment, understanding and prevention of adverse effects, particularly long term and short term adverse effects of medicines. This addresses what exactly is Pharmacovigilance?  What do we know of its benefits and risks, challenges and the future hold for pharmacovigilance in Indian medicine. Here the main focus on the aims and role of Pharmacovigilance in medicines regulation and their Partners. This article describes and discusses the National programme of pharmacovigilance and centre in India. There role in collecting the reports ADRs of medicines. Further effectiveness and risk assessments of therapies are been discussed. The important role played by health care professional, pharmaceutical industries, media, and programmes carried by WHO. Finally the conclusion describes the major challenges and achievements for the future pharmacovigilance programmeand toxicity is not socritical if botanicals are used in traditional forms (Harborne., 1998).

Brahmanand Group of Institutions, Bulandshahr (NCR) founded in the year 2010, has established its own identity in the field of Pharmacy, Management, Engineering and Hotel management. The UG and PG have been offered by the Institute in the field of Pharmacy, Architect, Management and Hotel Management.

Post: Director, Associate Professor, Assistant Professor