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Clinical courses

  • Revascularization Enhances Quality of Life for Patients with Chronic Limb Threatening Ischemia

    Over 200 million people around the world experience peripheral artery disease (PAD) – a condition caused by the narrowing of the blood vessels from the heart to the lower limbs that leads to pain when walking – and for roughly 1-in-10 this advances to chronic limb-threatening ischemia (CLTI), an advanced form of PAD. Those with CLTI often suffer severe pain even at rest, caused by fatty plaque buildup obstructing blood flow, typically to the leg or foot.

  • New insight into combatting drug-​resistant prostate cancer

    New research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by limiting the activity of coregulator proteins.

  • New drug prevents flu-related inflammation and lung damage

    Infection with the influenza virus leads to lung injury through inflammation over-activation that causes collateral damage to cells required for breathing. Such damage can be life-threatening, but scientists have a new preventative treatment. A team from St. Jude Children’s Research Hospital, University of Houston, Tufts University School of Medicine and Fox Chase Cancer Center created a drug that can prevent flu-induced lung injury.

  • Key Gene to Protection from Severe Illness & Death from COVID-19 Infections in Men Under Age 75

    Acertain variant of a key anti-inflammatory gene protects men under age 75 from severe illness and death when hospitalized from COVID-19, a genetic analysis of their blood shows.

  • New antibiotic class effective against multidrug-resistant bacteria

    Scientists at Uppsala University have discovered a new class of antibiotics with potent activity against multi-drug resistant bacteria, and have shown that it cures bloodstream infections in mice. The new antibiotic class is described in an article in the scientific journal PNAS.

  • India’s First Home-Grown Gene Therapy for Cancer developed by IIT Bombay

    The President of India Smt. Droupadi Murmu launched India’s first home-grown anti-Cancer CAR-T cell therapy and dedicated it to the Nation in the presence of the Governor of Maharashtra, Shri Ramesh Bais at the Indian Institute of Technology, (IIT) Bombay in Mumbai today. Also present on the occasion were Director, IIT Bombay, Prof. Subhasis Chaudhuri and Director, Tata Memorial Centre, Prof. Sudeep Gupta along with the key contributors including Prof. Rahul Purwar, Department of Bioscience and Bioengineering, IIT Bombay, and Dr. Hasmukh Jain and Dr.

  • Discovery of how limiting damage from an asthma attack could stop disease

    Scientists at King’s have discovered a new cause for asthma that sparks hope for treatment that could prevent the life-threatening disease.

  • Bariatric surgery linked to heart health improvements in people with severe obesity

    Bariatric surgery may result in significant cardiometabolic improvements, particularly among younger, female, or white people and those without comorbidities, according to new research published in the Journal of the Endocrine Society.

  • Heart Health Declines Rapidly After Menopause

    A woman’s cardiovascular risk can rise sharply after she goes through menopause, quickly catching up to men of a similar age and health profile, according to new findings presented at the American College of Cardiology’s Annual Scientific Session. Researchers said the study underscores the importance of recognizing and addressing early warning signs of heart disease risk in women as they lose the protective effects of estrogen after menopause.

  • Imfinzi significantly improved overall survival and progression-free survival for patients with limited-stage small cell lung cancer in ADRIATIC Phase III trial

    Positive high-level results of the ADRIATIC Phase III trial showed AstraZeneca’s Imfinzi (durvalumab) demonstrated a statistically significant and clinically meaningful improvement in the dual primary endpoints of overall survival (OS) and progression-free survival (PFS) in patients with limited-stage small cell lung cancer (LS-SCLC) who had not progressed following concurrent chemoradiotherapy (cCRT) compared to placebo after cCRT.

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