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SURFACTANTS: BASICS AND VERSATILITY IN FOOD INDUSTRIES

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About Authors:
Dr.Rakesh K. Sharma
M.Sc., M.Phil., Ph.D.
Assistant Professor, Applied Chemistry Department,
Faculty of Technology & Engineering,
The M. S. University of Baroda,
Vadodara, Gujarat, India.
rksharmamsu@gmail.com

Abstract
Surfactant, as an abbreviation of “surface active agent”, is an organic compound that is amphiphilic comprising both hydrophilic groups(commonly referred to as “polar heads”) and hydrophobic groups(“nonpolar tails”). Based on the electron charges of the polar head parts, surfactants are classified as anionic, cationic, nonionic, zwitterionic. Many other pecular class of compounds also categorized in the types of gemini, cyclodextrin based, polymeric surfactants etc. Due to their some interesting properties such as nontoxicity, higher rate of biodegradability, high foaming capacity and optimal activity at extreme conditions like temperatures, pH and salinity, surfactants have been increasingly attracting the attention of the scientific and industrial community. Biocompatible, biodegradable, and/or nontoxic emulsion-based formulations of surfactants have great potential for applications in the food preparation and processing. Basics of surfactants and mainly there way of utility as food emulsifiers in food industries is thoroughly discussed.


Admission to Ph.D Programme Academic year - 2014-15 in Sumandeep Vidyapeeth

Applications from eligible candidates are invited for admissions to PhD programs (Full time / in service) in all subjects/specialties of Medical, Dental, Physiotherapy, Nursing and Pharmacy faculty in SBKS Medical Institute and Research Centre, K M Shah Dental College and Hospital, College of Physiotherapy, College of Nursing and Department of Pharmacy of Sumandeep Vidyapeeth Deemed University for the Academic Year 2014-15.


Application are invited for Bachelor and Master degree in Pharmacy as Assistant Professor in Maharaja Sayajirao University

Applications are invited for the teaching post of Assistant Professors in various departments of the Faculties / Colleges of the University. The application form along with the details of vacancies can be downloaded from the University website msubaroda.ac.in. The duly filled application form along with all necessary enclosures and a bank payment challan/demand draft drawn in favour of “The Registrar, The M.S. University of Baroda” of Rs.1000/- (Rs.250/- for SC & ST candidates) must reach the Registrar, The M. S. University of Baroda, Fatehgunj, Vadodara - 390002 on or before 23rd January, 2014. No amount will be accepted either in Cash or by Money Order / Postal Order

Post: Assistant Professor


Walk in interview for the post of Officer/ Executive - Production in Sun Pharma

Sun Pharma ranks amongst India's largest pharma companies We’ve built a reputation for speciality therapy leadership and faster- than-industry growth over the last 30 years. From a modest beginning with five people, our team today exceeds 13,000 and growing, put manufacturing base now spans 25 sites across the world. With a market cap of over $ 16 billion, we’re also India’s most valued pharma brand. To keep pace with our growth plans, we require for our Formulation manufacturing plant at Halo! (Near Baroda):

Post: Officer/ Executive


NANOCOCHLEATE: NOVEL BYPASS OF CONVENTIONAL DRUG DELIVERY SYSTEM

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ABOUT AUTHORS:
Harsh Vyas1*, Tulsi Upadhyay1, Nirali Thakkar1, Kruti Patel1, Umesh Upadhyay2,
1Students, 2Faculty of pharmacy
Sigma Institute of Pharmacy,
Bakrol, Vadodara, Gujarat, India
*vyas123harsh@gmail.com, tulsiupadhyay90@gmail.com

ABSTRACT:
Nanocochleate is a novel lipid based drug delivery system offering systemic and oral delivery of various charged drug molecules. It is formed by negatively charged lipid bilayer. Nanocochleate can encapsulate drugs which are hydrophobic, positively charged, negatively charged and poor orally bioavailable. It is also very much beneficial for oral absorption for peptide drugs that possess a net positive charge. Nanocochleate is beneficial for molecules having binding sites inside the cell. The property that nanocochleates can facilitate cross membrane diffusion for charged and impermeable molecules finds wide application in drug delivery. Nanocochleate have been proven better than liposomes and more compatible with body environment. They differ from liposomes by its structure and compatibility to the body. Liposomes are lipid bilayer with aqueous inner environment and unlike liposomes nanocochleates are having charged lipid bilayer without aqueous environment and are multilayer lipid matrix i.e. Cochleate.

Various methods of its formulation, structure, merits demerits and wide range of application are described in this article.


Vacancies for Pharmacists in Department of Health & Family Welfare, NRHM - 992 posts

Department of Health & Family Welfare, Government of Gujarat has created wide network of health and medical care facilities in the state to provides primary, secondary and tertiary health care atthe door step of every citizen of Gujarat with prime focus on BPL families, marginalized population and weaker sections in rural and urban slum areas. Department also takes appropriate actions to create adequate educational facilities for medical and paramedical manpower in the state of Gujarat.


DESIGN, DEVELOPMENT AND CHARACTERIZATION OF pH SENSITIVE HYDROGEL FOR INTESTINAL DELIVERY OF PREDNISOLONE

ABOUT AUTHORS:
Patel Juhi D.*, Dr. A.K.Seth, Sachin P Chauhan, Nirmal Shah, Ankur Javia, Chintan Aundhia
Department of Pharmacy, Sumandeep Vidyapeeth University,
At & Po Pipariya, Ta- Waghodia, Dist. Vadodra-391760.(Gujarat) India
pateljuhi63@yahoo.com

ABSTRACT
In the present study pH sensitive hydrogel beads of prednisolone were prepared for intestine delivery system. The cross-linking reinforced chitosan- alginate complex beads were prepared by gelation of anionic sodium alginate, the primary polymer, with opposite charged counter ion to form beads which were further complexed with chitosan as a polyelectrolyte. The pH sensitive hydrogel beads were prepared by the unique ionotropic gelation method by applying 33 full factorial designs. In this present study, influence of various formulation parameters like drug: chitosan ration (1:0.5, 1:1, and 1:2), drug: sodium alginate ratio (1:1, 1:2, 1:3) and concentration of calcium chloride (3%, 4%, 5%) were studied. According to factorial design, total 27 batches were prepared and evaluated. The compatibility of drug with polymer was confirmed by Fourier transform infrared spectroscopy (FT-IR). All the formulation were subjected to percentage yield, drug entrapment efficiency, drug content, particle size, swelling study (In phosphate buffer pH 1.2 as well as in phosphate buffer pH 7.4), and in vitro drug release study. The data was found in the range of 72.00 ± 0.8 % to 92.00 ± 0.7 %,16.49 ± 0.2 % to 70.00 ± 0.2 %, 4.70 ± 0.4 to 13.30 ± 0.5,102.36 ± 2.27 to 138.48 ± 2.25 μm, , in phosphate buffer pH 7.4 between 109.00 ± 0.9 to 168.00 ± 0.4 and 106.60±0.6 to 136.00±0.3 in  phosphate buffer pH 1.2. From the results, B8 formulation was optimized. The prepared beads were enteric coated with 10% Eudragit S 100.  The surface morphology was studied by scanning electron microscopy (SEM) revealed spherical in shape with rough surface. It was reported that there was no swelling in acidic pH but increased in basic pH resulting in increased release of the drug in intestine. Hence it could be concluded that the prepared chitosan-sodium alginate hydrogel beads were satisfactory delivered to the stimulated intestinal fluid, which can be confirmed by further in vivo study.


Career as Production Incharge, Quality Control Incharge in GSFDSL

Gujarat State Forest Development Corporation Ltd. urgently requires at for its Ayurvedic Formlations Manufucturing Unit "DHANVANTRI" at GIDC, Ramagamdi, Por, Dist.Vadodara.


Walk in for experience candidates in QC, Production, Packaging department @ Sun Pharma | Require B.Pharm, M.Pharm, D.Pharm, B.Sc, M.Sc

Sun Pharma ranks amongst India's largest pharma companies We’ve built a reputation for speciality therapy leadership and faster- than-industry growth over the last 30 years. From a modest beginning with five people, our team today exceeds 13,000 and growing, put manufacturing base now spans 25 sites across the world. With a market cap of over $ 16 billion, we’re also India’s most valued pharma brand. To keep pace with our growth plans, we require for our Formulation manufacturing plant at Halo! (Near Baroda):


Job for B.Pharm, B.Sc as Area manager in Leading for Pharma Company | Nextus Solution

A renowned name, NEXTUS SOLUTIONS is a professionally managed organization engaged in offering highly acclaimed consultancy, Training and Placement. With our in- depth expertise and rich experience in the wide range of fields in India and abroad, we adopt a systematic and straightforward approach with every assignment of work we undertake. The effectiveness of our systematic and results-focused approach is reflected in our many long-term client relationships.
Leading for Pharma Company