ABOUT AUTHORS
Narinder Singh*, Raminder kaur
Department of Pharmaceutics
CT institute of Pharmaceutical Sciences,
Jalandhar, Punjab, India *Pharmacist.narinder@gmail.com
ABSTRACT
Current experimental investigation is dedicated to formulated alginate floating microbeads of Isoniazid as a model drug by ion cross-linking method or ion gelation technique using calcium chloride as cross-linking agent. Drug effectiveness might be influenced by blood plasma protein binding. The less bound drug is more viable it can cross cell membrane and diffuse. Protein binding can impact the drug’s biological half-life in the body. Isoniazid was first generation antibiotic which are used for the resistance is an obstacle to the treatment of tuberculosis disease and latent tuberculosis infection. The permeability of Isoniazid study using different membrane (Egg membrane and cellophane membrane). The IN VITRO drug release studies showed the optimized formulation of drug release 91 % in cellophane membrane and 88 % in egg membrane at 60 mins. The percentage buoyancy and swelling index of microbeads F1-F4 respectively 53-72% and 56-76%. The drug entrapment efficiency of the microbeads prepared from sodium alginate alone were found to be in the range of 52-71%.Experimental report revealed that Isoniazid loaded microbeads may act as ideal nano formulation with elaborated studies.
ABOUT AUTHORS
Narinder Singh*, Surya Prakash Gautam, NeelamKumari,Rupinder Kaur,Manpreetkaur
CT Institute of Pharmaceutical Sciences, Shahpur, Jalandhar, Punjab *pharmacist.narinder@gmail.com
ABSTRACT Virosomes are reconstituted viral envelopes that can fill in as vaccines and as vehicles for cell conveyance of different macromolecules. The prospect of drug delivery and targeting systems utilizing virosomes is an intriguing innovative work field. Since virosomes are biocompatible, biodegradable, non-poisonous and non-autoimmunogenuic; endeavors have been made to use them as antibodies or adjuvants and also conveyance frameworks for drugs and organic for remedial purposes. The achievement of virosomal medicate conveyance relies on upon strategy used to set up the typified bioactive materials and fuse them into the virosomes. Virosome innovation could conceivably be utilized to convey peptides, nucleic acids or, then again qualities and medications like anti-toxins, anticancer agents, and steroids.
Dr B R Ambedkar National Institute of Technology was established in the year 1987 as Regional Engineering College and was given the status of National Institute of Technology (Deemed University) by the Government of India on October 17, 2002 under the aegis of Ministry of Human Resource Development, New Delhi. Now the Ministry of Human Resource Development, Government of India has declared the Institute as “Institute of National Importance” under the act of Parliament-2007. A large number of reputed Industrial houses in the country visit the Institution and select the final year students as Engineers/ Management Trainees. As one of the National Institutes of Technology (NIT), the Institute has the responsibility of providing high quality education in Engineering, Technology and Sciences to produce competent technical and scientific manpower for the country. The Institute offers BTech, MTech, MSc, MBA and PhD programmes in the several disciplines of Engineering, Technology and Sciences.
Applications are invited for the one post of Project Assistant in SERB-DST funded research project entitled as “Development of New Platform for A³-Coupling and other Multicomponent Reactions towards Drug-Like Molecules using Transition Metal Catalysis”.
CT Group of Institutions, A pioneer educational group in Jalandhar invites applications for the following post(s) for their Jalandhar Campuses & upcoming University in Ludhiana:
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Applications are invited for the one post of JRF/SRF/RA in CSIR funded research project entitled as “Natural Product Inspired Design, Synthesis, and Anticancer Evaluation of β-Carboline Derivatives”. The date of walk-in-interview is 21st August 2015 (Friday) 2:00 pm onward in the office room of Head of Department Chemistry.
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Shrey Nutraceuticals & Herbals, with over two decades of successful existence is a leading manufacturer and exporter of high quality, research based range of nutrition and herbal products for the well-being and good health of the community. The Founder of the organisation, Mr. Virender Kumar has been very active in the pharmaceutical industry for more than 30 years and has been a specialist in the field of marketing medicines in various International markets and India.
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