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GUJCOST SPONSORED STATE LEVEL SEMINAR On Ethics: Essential Component of Clinical Research at Anand Pharmacy College
Anand Pharmacy College is one of the leading institute of Gujarat, established in 1998 by Shri Ramkrishna Seva Mandal. The institute is con-ducting All India Council for Technical Education (AICTE), New Delhi approved courses since 1998. The institute is accredited by NAAC-UGC with CGPA 2.68 and National Board of Accreditation (B.Pharm). Anand Pharmacy College offers B.Pharm, M.Pharm in Pharmaceutics, Pharmacology, Quality Assurance, Industrial Pharmacy, Pharmaceutical Technology & Pharmaceutical Quality Assurance and Ph.D. courses.
ICMR Sponsored National Level Seminar Bioanalysis in Clinical Research: Current Status and Challange in Anand Pharmacy College
SHRI RAMKRISHNA SEVA MANDAL is a registered society and a public trust established in the year 1954-55, managing more than 20 academic institutions. The trust believes in providing scientific and value based education by maintaining pace with the ever increasing needs of modern educational environment.
Walk in interview for the post of pharmacists under Anand district's District health society on fixed remuneration for 11 months of time period. Interested candidates are invited to attend interview with original documents(Marksheet, experience certificate etc.) and photocopies of them along with passport size photograph. Registration period for interviw will be morning 11:00 to 12:30 hrs.
Applications are invited for Research Fellow/Project Assistant position in A.R.College of Pharmacy & G. H. Patel Institute of Pharmacy
Applications are invited for one Research Fellow/Project Assistant position in a SERB, DST sponsored research project entitled 'Comparative evaluation of pharmacokinetic parameters & brain targeting efficiency of antipsychotic drug loaded nano-emulsion following intranasal and intravenous administration' (SR/FT/LS-135/2012 dated 11th January, 2013.)
Post: Research Fellow/Project Assistant
Charotar University of Science and Technology (CHARUSAT) is established with a vision to become a dynamic global institution in knowledge economy through excellence and impact of teaching, research and social contribution. It follows the mission to serve the society by striving to transform it through creation, augmentation, dissemination and perpetuation of knowledge.
Faculty of Pharmacy
Post: Associate Professor, Professor
GPSSB, ahmedabad invites online applications for direct recruitment of compunder or pharmacists (class-3). Candidates can apply from 25-01-2014 to 5-02-2014 (till night 11.59 hour). Candidate should upload recent photograph and signature in scan format.
No.of Post: 752
DRUG INDUCED MITOCHONDRIAL TOXICITY: MECHANISTIC DIVERSITY AND DELETERIOUS CONSEQUENCES FOR THE LIVER
Keyur S. Patel*, Mital Mehta
Department of Pharmacology,
Anand Pharmacy College, Anand.
Drug-induced liver injury (DILI) has become a leading cause of severe liver disease and withdrawal of an approved drug from the market. DILI accounts for acute liver failure, liver transplantation or death in the United States today. A recent retrospective study indicates that the risk of DILI is enhanced when the administered daily dosage is higher than 50 mg or when the drug undergoes significant liver metabolism. Hence airs a major clinical and regulatory challenge.
This review Sum up Direct mitochondrial impairment and Specific drug induced mitochondrial dysfunction, current mechanistic concepts of DILI in a 2-step model that limits its principle mechanisms to this main ways of initial injury. Umpteen Studies that evaluate the risk of hepatotoxicity from Statins in Hyperlipidemic Patients. In this article, It will review the pathogenesis of drug induced mitochondrial liver toxicity and deleterious consequences of Atorvastatin.
PHARMAFIESTA ‘13 on World Pharmacist Day Celebration at Anand Pharmacy College - 25th September, 2013
About the SRKSM Trust
Shri RamKrishna Seva Mandal is a registered society and a public trust established in the year 1954, managing more than 20 academic institutes. The trust believes in providing scientific and value based education by maintaining pace with the ever increasing needs of modern educational environment.
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DESIGN, DEVELOPMENT AND OPTIMIZATION OF OLMESARTAN MEDOXOMIL LIQUISOLID TABLETS USING CENTRAL COMPOSITE DESIGN
Swati k. Nagar*1, Dr. Harsha V. Patel1, Dr.Vishnu A. Patel2, Vinod V. Siju3
1Indukaka Ipcowala College of pharmacy, New V.V.Nagar
2ARCP, Vallabh vidhyanagar
3Anand Pharmacy College, Anand.
The aim of the present study was to investigate the applicability of liquisolid technique in improving the dissolution properties and solubility of olmesartan medoxomil (OLM) in a solid dosage form. This study was designed to optimize and evaluate the effects of different formulation variables: ratio of carrier to coating material (X1) and drug concentration (X2) on angle of repose (Y1), hardness(Y2), saturation solubility study (Y3) and cumulative percentage release at 10 min (CPR 10min)(Y4) of formulation using five level two factor central composite design. The quadratic model generated by the design is of the form: Y = A0 + A1X1 + A2X2 + A3X1X2 + A4X12 + A5X22 + E, where Y is the measured response associated with each factor level combination. Contour and response surface plots were depicted based on the equation given by the model. The optimized formula yields observed values close to the predicted values. The liquisolid tablets were formulated with liquid vehicles, poly ethylene glycol 400 (PEG400) at five drug concentrations, 10% w/w, 15% w/w, 20% w/w, 25% w/w and 30% w/w. Avicel PH102 was used as a carrier material, Aerosil 200 as a coating material and cross carmellose sodium as a disintegrant.In-vitro drug dissolution profiles of the liquisolid formulations were studied and compared with conventional formulation (olmezest), in simulated intestinal fluid (pH 6.8). The drug release rates of LS compacts were higher as compared to directly compressed tablets, which show significant benefit of LS in increasing wetting properties and surface area of drug available for dissolution. From this study it concludes that the LS technique is a promising alternative for improvement of dissolution property.