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  • A STUDY OF ADVERSE DRUG REACTIONS IN A TERTIARY CARE HOSPITAL OF PUNE

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    ABOUT AUTHOR
    Steffi Jerry Mammen
    Inamdar Multispeciality Hospital,
    Pune, Maharashtra

    ABSTRACT:
    Purpose: To study the adverse drug reactions (ADR’s) reported from wards and critical units in a tertiary care hospital of Pune. The adverse drug reactions were analyzed by Naranjo’s algorithm scale and Hartwig severity assessment scale and the outcomes were studied.
    Methods:  This observational and cross-sectional study was conducted for 6months from November 2016-May 2017 in an inpatient setting of a tertiary care hospital of Pune. The data collection was done only in wards and critical units. Patients of all age groups and either sex were included in this study. The adverse drug reactions were assessed for their causality and severity by performing the Naranjo’s algorithm scale and Hartwig’s scale respectively. The outcomes were studied. Data analysis was done by descriptive statistics.

    Result: Total 50 adverse drug reactions were reported from wards and critical units. 21-30 years age group was reported to have more adverse drug reactions. The most commonly affected organ is the Skin 32 (71.11%), followed by Respiratory system 3 (6.66%) and nervous system 3 (6.66%). Vancomycin 5 (20%) was the drug having majority of the ADR’s. The commonly reported ADR in this study was rash and itching 29 (64.44%). According to Naranjo’s algorithm scale, 23 (51.11%) suspected ADR’s were probable, 17 (37.77%) ADR’s were possible and 5(11.11%) were definite. As per Hartwig’s severity assessment scale, majority of the ADR’s were mild 21 (46.66%), followed by moderate 20 (44.44%) and severe 4 (8.88%). The outcome of the ADR’s was all recovered 38 (84.44%) during the study period.
    Limitations: Study was conducted only in wards and critical units not in all departments of the hospital. Some of the ADR’s have gone un-reported by Resident Medical Officer (RMO) due to increased work pressure, lack of awareness or busy environment.

  • Opportunity in OSD/Sterile at Cipla

    One of the top global pharmaceuticals companies in India, uses latest technology for high quality & affordable medicines for all patients.

    Post : OSD/Sterile

  • Central Drugs Testing Laboratory invites applications for post of Senior Scientific Officer for National Tobacco Control Programme

    The CDTL, Mumbai is one of the National Statutory Laboratories of the Government of India, functioning under the administrative control of the Drugs Controller General (India), Central Drugs Standard Control Organization (CDSCO), Directorate General of Health Services, Ministry of Health and Family Welfare, New Delhi.

    Post: Senior Scientific Officer - I

  • Work as Affiliate Safety Representative at Abbott India Limited | M.Pharm, M.Sc, B.Pharm - experienced candidates only

    Abbott India Limited is a subsidiary of Abbott Laboratories, USA, a global, iversified health care company devoted to the discovery, development, manufacture and marketing of pharmaceutical, diagnostic, nutritional and hospital products. The company now employs approximately 70,000 people and markets its products in 130 countries worldwide.

    Post : Affiliate Safety Representative

  • Career as Country Portfolio Manager at Pfizer

    Founded in 1849, Pfizer is the world's premier biopharmaceutical company taking new approaches to better health.  We discover, develop, manufacture and deliver quality, safe and effective prescription medicines to treat and help prevent disease for both people and animals. We also partner with healthcare providers, governments and local communities around the world to expand access to our medicines and to provide better quality health care and health system support. At Pfizer, colleagues in more than 90 countries work every day to help people stay happier and healthier longer and to reduce the human and economic burden of disease worldwide.

    Post : Country Portfolio Manager

  • Opportunity to work at Piramal Enterprises as Pharmacovigilance Executive

    Piramal Enterprises Limited is the flagship company of the Piramal Group.  Starting from the mid-1980s, PEL has shifted its focus from the textiles industry, and established its entrepreneurial credentials in Pharma, Information Management, and Financial Services. It has grown organically and inorganically and often made contrarian business calls.

    Post : Executive – Pharmacovigilance

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  • FORMULATION AND EVALUATION OF MICROENCAPSULATED GLIMEPIRIDE PRODUCED BY THE EMULSION - SOLVENT EVAPORATION METHOD

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    ABOUT AUTHORS
    P. S. Bhandare 1, V.G Gharge 2.
    1*Department of Pharmacology,
    GIPER, Satara, Maharashtra, India.
    2 Department of Pharmaceutics,
    GIPER, Satara
    , Maharashtra, India.

    ABSTRACT
    "The objective of the present investigation was to formulate and evaluate microencapsulated  Glimepiride produced by the emulsion - solvent evaporation method. Microparticles were prepared using Eudragit RLPO by emulsion solvent evaporation and characterized for their micromeritic properties, encapsulation efficiency, particle size, In vitro release studies were performed in phosphate buffer (pH 7.4). The resulting microparticles obtained by solvent evaporation method were free flowinging nature. The mean particle size of microparticles ranges from 140.40 - 173.90 μm and encapsulation efficiency ranges from 90.46 – 93.09%. Eudragit RLPO microparticles containing Glimepiride could be prepared successfully by using an emulsion solvent evaporation technique, which will not only sustain the release of drug but also manage complicacy of the diabetes in a better manner.

  • Job for Pharmacist at Malegaon Municipal Corporation

    Malegaon Municipal Corporation, National Urban health Mission release a new vacancy notification for the recruitment of Pharmacist.

    Post : Pharmacist

  • Roche Pharmaceuticals looking for Medical Value Partner | M.Pharm, Ph.D

    Roche Pharmaceuticals, India, has been disseminating scientific knowledge pertaining to innovative medicines to the medical fraternity. We have products in therapeutic areas such as Oncology, Virology, Nephrology, Transplantation, Anemia... Not translated Arthritis. In recognition of its contributions in Oncology, Roche India has been awarded the ‘Best Oncology Company of the Year,' by Frost & Sullivan at the India Healthcare Excellence Awards for the years 2011, 2012 and 2014.

    Post : Medical Value Partner

  • Career for M.Pharm as Senior Manager in Pharma Solutions at BASF

    BASF, diversity is one of the essential keys to business success and the well-being of our employees. We promote an inclusive culture that accepts the diversity of people, experiences and capabilities. By embracing talents and abilities of all kinds, we aim to boost creativity and motivation, and enhance our teams’ performance.

    Post : Senior Manager - Pharma Solutions South Asia

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