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Karnataka Antibiotics & Pharmaceuticals Ltd., (KAPL) Bangalore is a Government Enterprise. From a modest beginning in 1984, KAPL has grown from strength to strength in the areas of manufacturing and marketing of various life saving and essential drugs. With an ISO accredition from KPMG, Netherlands, KAPL is recognised for its total commitment to quality and services in domestic and international markets. On profit from inception, KAPL facilities are approved by many international clients.
Post: PROFESSIONAL SERVICE REPRESENTATIVES [PSRs]
Panacea Biotec is a leading research based Health Management Company, with an annual turnover of approx. Rs. 830 Crores. We are engaged in research, development, manufacture & marketing of Vaccines, Bio-Pharmaceuticals and Pharmaceuticals (Rx & OTC) of international quality and Health Services. All Panacea Biotec plants are accredited by international agencies and they follow current Good Manufacturing Practices, as per WHO guidelines.
Job for M.Pharm, Ph.D as Assistant Professor, Principal, Associate Professor, Professor & Head @ Koneru Lakshmaiah University
The Koneru Lakshmaiah Charities was established as a trust in the year 1980 with its official address at Museum road, Governorpet, Vijayawada, Andhra Pradesh - 520 002 and started KL College of Engineering in the Academic year 1980-81. The trust was converted into a Society by the name Koneru Lakshmaiah Education Foundation in the year 1996. The KL College of Engineering has attained autonomous status in the year 2006 and in February 2009, the Koneru Lakshmaiah Education Foundation Society was recognized as Deemed to be University. In short Koneru Lakshmaiah Education Foundation is named as K L University.
Post: Assistant Professor, Principal, Associate Professor, Professor & Head
*Md. JahaSultana, P. Vijaya Sri, G.Alekhya, S.VenkateswaraRao, Chaitanya PrasadMeher
Department Of Pharmaceutical Analysis
Vijaya Institute of Pharmaceutical Sciences For Women
Enikepadu, Vijayawada-521108, Andhra Pradesh, India
Over a past decades, nuclear magnetic resonance (NMR) has progressed rapidly in improvement of experimental method and development of novel approaches. NMR is a research technique that exploits the magnetic properties of certain atomic nuclei. Of all the spectroscopy methods, NMR is the only one of which a complete analysis and interpretation of the entire spectrum is normally excepted. Although larger amounts of samples are needed when compared with mass spectroscopy, NMR is non-destructive and with modern instruments good data may be obtained from samples weighing less than a milligram. In this review a brief introduction to the NMR is given which includes instrumentation, parameters influencing NMR and applications.
A CRITICAL REVIEW ON PHARMACEUTICAL ANALYSIS OF NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY (HETCOR SPECTROSCOPY)
Reshma. K*, M.Muthukumaran*, B.krishnamoorthy, Amreen Nishat
Montessori Siva sivani Institute of Science&Technology- College Of
Vijayawada, Andhrapradesh-521 230
Nuclear magnetic resonance (NMR) has progressed rapidly over the last decade as a result of improved experimental technology and development of novel approaches. NMR spectroscopy has evolved into an important technique in support of structure-based drug design. It was most useful as a technique to provide structural information regarding protein drug targets and target–ligand interactions. More recently, it has been shown that NMR may be used as an alternative method for identification of small molecule ligands that bind to protein drug targets. High throughput implementation of these experiments to screen small molecule libraries may lead to identification of potent and novel lead compounds. NMR as a probe of microscopic dynamic behaviour through relaxation and direct diffusion measurements over a wide temperature range is examined.
Area sales executive/ Medical representative in Synergy Diagnostics | B.Pharm, B.Sc, MBA (marketing) or Any
NOVEL RP-HPLC METHOD DEVELOPMENT AND VALIDATION OF LOSARTAN POTASSIUM AND AMLODIPINE DRUGS IN PURE AND PHARMACEUTICAL DOSAGE FORMS
1Kumari Jyothsna*, 2N.Chandana
1,2Department of Pharmaceutical Analysis and Quality Assurance,
Nimra College of Pharmacy, Jupudi, Vijayawada, A.P, India
A fast, robust and accurate RP-HPLC method was developed and validated for simultaneous determination of Losartan potassium and Amlodipine in tablets. The mobile phase was mixture of aqueous Tri ethyl amine with pH 2.0 and Acetonitrile(70:30), effluent flow rate monitored at 1.0 ml/min. the stationary phase was C18 column, 3µm(4.6×250mm). The solutions of standard and the sample were prepared in methanol. The retention times was found to be 2.916min and 5.214min for Losartan potassium and Amlodipine respectively at 246nm. Calibration graphs constructed at their wavelengths of determination were linear in the concentration range of 50-150µg/ml. The percentage assay for Losartan potassium and Amlodipine were found to be 101% and 100%respectively. The method was validated and it was found to be accurate, precise, linear and reproducible as per ICH guidelines.
A NOVEL RP- HPLC METHOD DEVELOPMENT AND VALIDATION OF ATORVASTATIN AND FENOFIBRATE IN BULK AND PHARMACEUTICAL DOSAGE FORMS
1Vinjam Swathi* 2Nanda Kishore Agarwal
1M pharmacy, Department of Pharmaceutical Analysis and Quality Assurance, Nimra College of Pharmacy, Jupudi, Vijayawada, A.P, India
2Professor and head of the department of pharmaceutical chemistry, Nimra College Of Pharmacy, Jupudi, Ibrahimpatnam, Vijayawada, A.P, India
The present investigation describes about a simple, economic, selective, accurate, precise reverse phase high performance liquid chromatographic method for the simultaneous estimation of Atorvastatin and Fenofibrate in pure and pharmaceutical dosage forms. Atorvastatin and Fenofibrate were well separated using a Thermohypersil BDS C18column of dimension 100 × 4.6, 5µm and Mobile phase consisting of Methanol: Water (Adjusted with orthophosphoric acid to pH-2) in the ratio of 40:60v/v at the flow rate 1 ml/min and the detection was carried out at 274nm with PDA detector. The Retention time for Atorvastatin and Fenofibrate were found to be 1.438, 2.949 respectively. The developed method was validated for recovery, specificity, precision, accuracy, linearity according to ICH guidelines. The method was successfully applied to Atorvastatin and Fenofibrate combination pharmaceutical dosage form.
METHOD DEVELOPMENT AND METHOD VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF CEFTAZIDIME PENTAHYDRATE AND TAZOBACTAM SODIUM IN BULK AND DOSAGE FORMS RP-HPLC
1S. Amareshwari*, 2Dr. Nanda Kishore Agarwal
1M.Pharm, Department of pharmaceutical analysis, Nimra College Of Pharmacy
2Professor and head of the department of pharmaceutical chemistry, Nimra College Of Pharmacy,
Jupudi, Ibrahimpatnam, Vijayawada
The present investigation describes about asimple rapid, accurate, precise and reproducible validated reverse phase HPLC method was developed for the determination of Ceftazidime pentahydrate and Tazobactam sodium in bulk and pharmaceutical dosage forms. The quantification was carried out using Hypersil BDS C18 (150 X 4.6mm, 5 µm) columnrun in isocratic way using mobile phase comprising of phosphate buffer pH 3.0, acetonitrile, and tetrahydrofuran in the ratio of 60:30:10 with a detection wavelength of 205nm and injection volume of 20µL, with a flow rate of 1.0ml/min. The retention times of the drugs were found to be 3.490min and 2.353min. The linearity ranges of the proposed method lies between 60-140mcg/mL and 7.5-17.5mcg/mL for Ceftazidime pentahydrate and Tazobactam sodium with correlation coefficient of r2=0.999 for both. The assay of the proposed method was found to be 99.38% and 99.26%. The recovery studies were also carried out and mean % Recovery was and found to be 99.91% and 100.84%. The % RSD from reproducibility was found to be <2%. The proposed method was statistically evaluated and can be applied for routine quality control analysis of Ceftazidime pentahydrate and Tazobactam sodium in bulk and in Pharmaceutical dosage form.
Uttarakhand Technical University, a state government university, Dehradun was established on 27th January 2005 by Govt. of Uttarakhand through the Uttarakhand Technical University Act 2005. The University is the only affiliating University of the state for various private and Govt. institutions. The M.Pharm programme was started in the year 2009. The faculty of pharmacy of the university invites applications for Regular-AICTE approved M.Pharm programme.