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Anti Adrenergic drugs

 

Clinical courses

 

                          Anti-Adrenergic Drugs


Anti-adrenergic agents are those which act on adrenergic receptors and block their activity. It reduces sympathetic out flow and antagonised them.


Table of Content

       α Blockers

      
β Blockers



α blockers:

These are agents which antagonised α receptors and decreases sympathetic activity.
Non equilibrium type, Phenoxybenzamine.

Equilibrium type,

Non selective: ergotamine, ergotoxine, tolazoline, chlorpromazine.

Selective:

α1 selective: prazosin, doxazocin.

α2 selective: yohimbine.
    

β Blockers:

These are the agents which block the β-receptors present in the body.

β-receptor antagonists are classified as, Nonselective and Selective.

Non selective1 & β2):

Membrane stabilizing activity without intrinsic sympathomimetic activity: Propranolol, Timolol, Sotalol.

Membrane stabilizing activity with intrinsic sympathomimetic activity: Pindolol.

With additional α blocking activity: Labetalol, Carvedilol.

Selective:

β1 selective: Atenolol, Metoprolol, Acebutolol, Esmolol.

β2 selective: Butoxamine.