Pune

Agharkar Research Institute (ARI) is an autonomous, grant-in-aid research institute of the Department of Science and Technology (DST), Goverment of India. It was established in 1946 by the Maharashtra Association for the Cultivation of Science as MACS Research Institute and renamed as ARI in 1992 in honour and memory of its founder Director, late Professor S.P. Agharkar.

About Authors:
1) Mr Jaesh N.Jadhav
M.Pharm,Sinhagad Institute of pharmacy,Pune.
2) Mr. J.G. Chandorkar*.
Head Analytical development laboratory,
Indofil Industries limited,Thane
*Jayant.chandorkar@rediffmail.com

Abstract
A present work describes a simple & accurate reversed phase HPLC Method for the simultaneous estimation of Ortho Chlorophenol [OCP], 2,6 – Dichlorophenol [DCP], 1-(2,6-Dichlorophenyl) indolin-2-one [VTCL], 1(2,6-Dichlorophenyl) N-Phenyl, N-Chloro Acetyl, 2,6-Dichloro Aniline [VTDL], 1(2,6-Dichlorophenyl) ether [DCPE], 1(2,6-Dichlorophenyl) amine [DCPA] in Diclofenac Sodium bulk manufacturing. This paper describes a new rapid, easy Isocratic reversed phase HPLC method for the separation and estimation of six intermediates and Diclofenac Sodium. The primary purpose of this study is to compile HPLC data on the determination of these seven products, the compilation of such HPLC data being useful as reference guide.

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A service oriented export trade company specialized into overseas distribution and manufacturing of pharmaceutical formulations, active pharmaceutical ingredients and related chemicals. Right since the inception of this company since 1985 we are involved in the same activity.
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