Skip to main content

Study of drug metabolism by capillary electrophoresis at Ku Leuven

 

Clinical courses

 

Clinical courses

The Laboratory of Molecular Cell Biology belongs to the department of Biology in the group of Science & Technology. This laboratory is also a department of the Flemish Institute for Biotechnology (VIB, vib.be). Prof. Van Dijck is one of the two professors in this unit. An important research topic in his laboratory is the understanding of the development of fungal biofilms. We mainly focus on Candida albicans and Candida glabrata. In the framework of a Belgian government funded multipartner research project, we have now an opening for a highly motivated PhD student to work on the role of nutrient sensing mechanisms and their importance during single species (Candida albicans) and mixed (C. albicans + Staphyloccocus aureus) species biofilms.

For Pharmaceutical Analysis we are looking for a PhD candidate. The project is part of the EU-funded project ARIADME: Analytical Research in ADME profiling ( pharm.kuleuven.be/pharbio/ariadme). ARIADME is a Marie Curie project which involves 4 academic centers and 10 industrial partners. The PhD candidate will be enrolled in the KU Leuven doctoral school program and is expected to contribute to network wide training events of the ARIADME project.

Project
The scientific objectives and tasks of this PhD research project can be summarized as follows.

Objectives:
To elaborate a novel analytical system for early metabolic profiling based onin-line integration of metabolic phase I or phase II enzymes and magneticnano particles (MNPs) into capillary electrophoresis (CE).

Main Tasks:
- Create enzymatic bioreactors for the most important phase I and II metabolic enzymes by covalent chemical bonding of the enzymes to MNPs
- Establish a CE-bioreactor platform featuring low enzyme and analyte consumption

Profile
The highly motivated candidate must hold an MSc degree in Pharmaceutical Sciences, Biomedical Sciences or a related field. He/she should have less than 4 years of research experience and must not have resided or carried out their main activity in Belgium for more than 12 months in the 3 years immediately prior to their recruitment.

Interested?
For more information please contact Prof. dr. Ann Van Schepdael, mail: ann.vanschepdael@pharm.kuleuven.be.
Applications should include Resume/CV and Cover Letter.

You can apply for this job no later than August 16, 2013 via the online application tool

FIND MORE INFO

See All   B.Sc Alerts   M.Pharm Alerts   Ph.D Alerts

See All   Other Jobs  in our Database

Subscribe to Pharmatutor Job Alerts by Email