Bangalore

Novozymes is a biotech company with a strong focus on enzyme production. We are committed to changing the very foundations of our industrial system for the better by using industrial biotechnology.

ABOUT AUTHORS:
Monowar Hussain*, Geethalakshmi. A, Diwakar Srinivas G.
Department Of Pharmaceutics,
The Oxford College of Pharmacy,
Bangalore, Karnataka, India- 560068
*monowar250@gmail.com

ABSTRACT:
Carbopol⁹³⁴ (C⁹³⁴) pH-specific polymer and Pluronic-F127 (PF-127) polymer can be used to increase the bioavailability and therapeutic value of β-blockers (Betaxolol HCl) in glaucoma treatment by using in situ gelling system. Nine formulations (F1,F2,F3,F4,F5,F5,F6,F7,F8,F9) with different concentrations of C⁹³⁴  and PF127 were tested for Clarity, pH, Gelling Capacity, Gelation Temperature, Eye irritation, Isotonicity, in-vitro diffusion, Viscosity and Sterility. Compatibility test was performed using FT-IR for all the formulations. F3 with C⁹³⁴ (0.4% w/v) and PF127 (15% w/v) passed the entire test and gave the best result.

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Novozymes is a biotech company with a strong focus on enzyme production. We are committed to changing the very foundations of our industrial system for the better by using industrial biotechnology.

Novozymes is a biotech company with a strong focus on enzyme production. We are committed to changing the very foundations of our industrial system for the better by using industrial biotechnology.

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Novozymes is a biotech company with a strong focus on enzyme production. We are committed to changing the very foundations of our industrial system for the better by using industrial biotechnology.

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