Claris Lifesciences is one of the largest sterile injectables pharmaceutical companies in India with a market presence in 91 countries worldwide. We primarily manufacture and market products across multiple markets, and therapeutic segments. A significant majority of these products are generic drugs that are capable of being directly injected into the human body and are predominantly used in the treatment of critical illnesses.

Post: ASM (Medical Representative)

This Institute started as “Occupational Health Research Institute” (OHRI) in the year 1966 and was re-christened as “National Institute of Occupational Health” (NIOH) in 1970 presently located in the Eastern part of Ahmedabad. Two Regional Occupational Health Centers (ROHCs) were started at Bangalore in 1977 and at Kolkata in 1980.

RASA Life Science Informatics

Invites you to 3 Day Workshop in In-Silico Drug Discovery and Advance Chemoinformatics (28th-30th Sept. 2012).
Space is limited, so be sure to enroll now!

Salient Features of the Workshop
Workshop groups will study problems with hands-on examples using computational chemistry methods and discuss issues highlighted by examples and Case Studies in drug discovery presented by instructors. A Case Study set with a focus on chemical database creation and filtering drug like compounds will be used to link all workshop activities throughout the workshop.

On completion of this workshop you will be expertise in :
* Hands on training on commercial softwares of Drug discovery
* Application  of Chemoinformatics in drug discovery
* Interaction and guidance from eminent scientist & professionals  from industry & research labs
* Training from industry expertsfrom Chemoinformatics & drug discovery  informatics domain.
* Analyzing chemical fingerprint
* Pharmacophore based Virtual Screening of compounds
* Screening of library compound against selected target
* Analyzing Docking Results
* Molecular Modeling &Dynamics
* Steps involved from Lead Optimization to Final Candidate Drug.
* Generating Knowledge from structure and different chemical databases
* Using various chemical structure drawing and visualization tools
* Digitizing your chemical Data.
* Storing molecules in wide array of format
* Awards for top 2 groups

Speakers:

Audience
Graduate/ post-graduate students, professionals, faculties from Organic chemistry, Pharmacy, Bioinformatics, Biotechnology, Agrochemical, Microbiology, Chemical ,life sciences etc from  Industries and institutions will benefit the most from getting hands-on experience

Venue:
Alard Charitable Trust
Alard school of Pharmacy, Survey No. 50, Marunje,
Near Rajiv Gandhi IT Park, Hinjewadi, Pune - 411 057,
Maharashtra, India
Tel:  02065600408, 07875692349/7875793891

For any queries contact us at
RASA Life Science Informatics
301, 3rd Floor, Dhanashree Apartment,
Opposite Chittaranjan Vatika, Model Colony,
Shivaji Nagar, Pune - 411016.
Tel:  02065600408, 07875692349/7875793891/8411927535
or email us at workshop@rasalsi.com

Torrent Pharmaceuticals Limited, is a dominant player in the therapeutic areas of cardiovascular (CV) and central nervous system (CNS) and has achieved significant presence in gastro-intestinal, diabetology, anti-infective and pain management segments.

Torrent Pharmaceuticals Limited, is a dominant player in the therapeutic areas of cardiovascular (CV) and central nervous system (CNS) and has achieved significant presence in gastro-intestinal, diabetology, anti-infective and pain management segments. Torrent Pharma’s competitive advantage as a manufacturer stems from its world-class manufacturing facilities.

About Authors:
CHIRAG S. RAJPARA*¹, JAWED AKHTAR¹, AMIT KHANDHAR²
1. Department of Quality Assurance, School of Pharmaceutical Sciences, Jaipur National University, Jagatpura, Jaipur-302025, Rajasthan, India.
2. Zydus cadila pharma, moraiya,ahmedabad.
*chiragrajpara2601@gmail.com

ABSTRACT
* A simple, specific, accurate and stability-indicating reversed phase high performance liquid chromatographic method was developed for simultaneous estimation of Tadalafil and Dapoxetine HCL, Water Symmetry C-18 (150 x 4.6 mm),5 µ and a mobile phase composed of Buffer : Acetonitrile (65:35)

* The retention time of Tadalafil and Dapoxetine HCL were found to be10.08 and 4.45 min respectively. Linearity was established for Tadalafil and Dapoxetine HCL in the range of 8.0-60 μg/ml and 24.0-180.0 μg/ml respectively. The percentage recovery of Tadalafil and Dapoxetine HCL were found to be in the range of 99.7-100.6% and 98.07-99.09% respectively. The drug was subjected to acid and alkali hydrolysis, oxidation, dry heat and photolytic degradation. The degradation studies indicated, Tadalafil showed degradation in acid and alkali while it was found stable in H₂O_2, photolytic and in presence of dry heat and Dapoxetine showed degradation in thermal and peroxide while it was found stable in rest of parameters . The degradation products of Tadalafil and Dapoxetine HCL in acidic, alkaline conditions were well resolved from the pure drug with significant differences in their retention time values. This method can be successfully employed for the quantitative analysis of Tadalafil and Dapoxetine HCL in bulk drugs and formulations.

Soranus was a Greek physician from Ephesus in 1st and 2nd century. He practiced in Alexandria and subsequently in Rome, and was one of the chief representatives of the Methodic school of medicine. Several of his writings still survive most notably his four-volume treatise on gynaecology and a Latin translation of his on acute and chronic diseases. He belonged to the Methodic School and was one of the most eminent physicians of that school. Little else is known about his life, except that he passed some time in Aquitania for the purpose of treating some skin diseases which were very prevalent there at the time.

About Authors:
Roshni Patel*, Prof. Arun Parikh, Prof. Vijayalakshmi  Gudaparthi
Department of Pharmaceutical Chemistry, L.J.Institute of Pharmacy,
S.G.Highway, Ahmedabad-382210
*roshanimpharm@gmail.com

ABSTRACT
Medicinal chemistry involves chemical aspects of identification, and then systematic, thorough synthetic alteration of new chemical entities to make them suitable for therapeutic use. Indazoles have an important role in medicinal chemistry. Indazole  nucleus is an important class of nitrogen containing heterocyclic widely used as key building block for the synthesis of various pharmaceutically important agents. Indazole possess wide range of biological activities such as bactericidal, fungicidal, analgesic, antihypertensive, anti-inflammatory and antitumor. In the present study we have synthesized some novel 3,3a,4,5-tetrahydro-2-(substituted benzenesulphonyl)-3-(substituted phenyl)-2H-benzo[g]indazoles, by condensation of  1-tetralone with different substituted aromatic aldehydes and the resulted 2-(substituted benzylidene)-3,4,-dihydronaphtalen-1-ones on reaction with hydrazine hydrate in methanol followed by treatment with different substituted sulfonyl chlorides in pyridine gave the titled compounds.The synthesized compounds were characterized by IR, NMR and Mass spectral analysis. All newly synthesized derivatives were evaluated for antibacterial activity against  gram + ve and gram-ve bacteria B.cereus, S.aureus and E.coli respectivelyand antifungal activity againstC.albicans and all the synthesized compounds showed significant antibacterial and antifungal activity.

One time career opportunity for Fresher life sciences candidates: M.Sc, B.Pharm, M.Pharm. MBBS, BDS, MD, B.Tech, M.Tech, to join as Project Trainee in BioCampus, GVK Bio - 20 Vacancies

Torrent Pharmaceuticals Limited, is a dominant player in the therapeutic areas of cardiovascular (CV) and central nervous system (CNS) and has achieved significant presence in gastro-intestinal, diabetology, anti-infective and pain management segments. Torrent Pharma’s competitive advantage as a manufacturer stems from its world-class manufacturing facilities.