Ahmedabad

U.N. Mehta Institute of Cardiology and Research Center (UNMICRC) is a Grant-in-aid cardiac institute promoted by Government of Gujarat in Ahmadabad, Gujarat. The institute is affiliated to B J Medical College, Civil Hospital Campus (Medicity), Asarwa which is a Government Medical College. We currently have 450 beds that includes a state-of-the-art 250 bed cardiac unit with 4 Cardiac Flat Panel Cathlab (Including Hybrid Cath Lab with Cardiac OT), and 5 Cardiac Operation Theater including a Pediatric OT and a Thoracic OT with most advanced medical equipment.

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ABOUT AUTHORS:
Krupa Mehta, Nitu Changoiwala, Sanjay C. Modi, Dr. Mukesh C. Gohel, Dr. Rajesh K. Parikh
L. M. College of Pharmacy, Navrangpura,
Ahmedabad, Gujarat-380009, India

ABSTRACT:
Objective:
To Formulate, Develop and Optimize fast dispersible oral films of Domperidone maleate.
Materials and Methods:
Fast dispersible films of Domperidone maleate were prepared using solvent casting method. Films were formulated using Hydroxy Propyl Methyl Cellulose (HPMC-E5) as a film forming agent, PEG-400 as a plasticizer. A 3² full factorial design was applied systematically to optimize the drug release and folding endurance. The concentration of HPMC-E5 (X1) and concentration of PEG-400 (X2) were selected as independent variables.
  The Percentage Drug Release in 5 minutes (Y1) and Folding endurance (Y2) were selected as dependent variables. The prepared films were evaluated for Thickness, Folding endurance, Tensile Strength, Disintegration time, In vitro drug release and Drug content uniformity.  DSC studies were conducted for drug-excipient interactions.
Results: Films prepared were found to be of good quality fulfilling all the requirements. Regression analysis and numerical optimization were performed to identify the best formulation. Formulations F10 prepared with 2.7% HPMC-E5 and 20% PEG-400 was found to be the best formulation with 96% Drug release in 5 minutes and folding endurance 24.
Discussion: X₁ and X₂ significantly affected the Percentage Drug Release in 5 minutes (Y1) and Folding endurance (Y2). Percentage Drug Release decreased as the concentration of HPMC-E5 and PEG-400 increased. Folding endurance increased as the concentration of HPMC-E5 and PEG-400 increased.
Conclusions: Fast dispersible films of Domperidone maleate were successfully formulated by Solvent casting technique with immediate onset of action & improved patient compliance.

The National Institute of Pharmaceutical Education and Research (NIPER) has been created as a centre of excellence for higher education, research and development in pharmaceutical sciences. NIPER, Rae Bareli at ITI campus, Rae Bareli under the mentoring Institute of Central Drug Research Institute, Lucknow invites eligible candidates for following positions on purely temporary basis on contract initially for a period of 1 year which can be extended further. The selected candidates shall have no claim for regularization against any regular post either in NIPER or CDRI.

Department of Health & Family Welfare, Government of Gujarat has created wide network of health and medical care facilities in the state to provides primary, secondary and tertiary health care atthe door step of every citizen of Gujarat with prime focus on BPL families, marginalized population and weaker sections in rural and urban slum areas. Department also takes appropriate actions to create adequate educational facilities for medical and paramedical manpower in the state of Gujarat.

A renowned name, NEXTUS SOLUTIONS is a professionally managed organization engaged in offering highly acclaimed consultancy, Training and Placement. With our in- depth expertise and rich experience in the wide range of fields in India and abroad, we adopt a systematic and straightforward approach with every assignment of work we undertake. The effectiveness of our systematic and results-focused approach is reflected in our many long-term client relationships.
Leading for Pharma Company

Post: Medical Representative

The National Institute of Pharmaceutical Education and Research (NIPER) has been created as a centre of excellence for higher education, research and development in pharmaceutical sciences. NIPER, Rae Bareli at ITI campus, Rae Bareli under the mentoring Institute of Central Drug Research Institute, Lucknow invites eligible candidates for following positions on purely temporary basis on contract initially for a period of 1 year which can be extended further. The selected candidates shall have no claim for regularization against any regular post either in NIPER or CDRI.

The project sponsored by Department of Science and Technology is entitled “Photoprocesses of donor-acceptor substituted polyenes in ionic liquid media” The JRF will be mostly work on synthesis of small molecules and ionic liquids.

Post: Junior Research Fellow

A renowned name, NEXTUS SOLUTIONS is a professionally managed organization engaged in offering highly acclaimed consultancy, Training and Placement. With our in- depth expertise and rich experience in the wide range of fields in India and abroad, we adopt a systematic and straightforward approach with every assignment of work we undertake. The effectiveness of our systematic and results-focused approach is reflected in our many long-term client relationships.
Leading for Pharma Company

The following post is to be filled up under time bound research project entitled “Health of the workers working in Iron Foundries & Ceramic Industries” sponsored by Government of Gujarat at National Institute of Occupational Health, Ahmedabad. The post is purely on temporary ad-hoc & Contractual basis for six months only and coterminates with the project, or whichever is earlier:-

Post: Research Assistant (One)