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Walk in interview for Medical Clinical Coordinator in U.N. Mehta Institute of Cardiology and Research Center

U.N. Mehta Institute of Cardiology and Research Center (UNMICRC) is a Grant-in-aid cardiac institute promoted by Government of Gujarat in Ahmadabad, Gujarat. The institute is affiliated to B J Medical College, Civil Hospital Campus (Medicity), Asarwa which is a Government Medical College. We currently have 450 beds that includes a state-of-the-art 250 bed cardiac unit with 4 Cardiac Flat Panel Cathlab (Including Hybrid Cath Lab with Cardiac OT), and 5 Cardiac Operation Theater including a Pediatric OT and a Thoracic OT with most advanced medical equipment.

Post: Medical Clinical Coordinator


RAPID AND SELECTIVE UV SPECTROPHOTOMETRIC AND RP-HPLC METHODS FOR DISSOLUTION STUDIES OF IVABRADINE CONTROLLED-RELEASE FORMULATIONS

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ABOUT AUTHORS:
Sagarika Panda1*, Srikanta Patra2
1 Jawaharlal Nehru Technological University Hyderabad, Kukatpally, Hyderabad, Andhra Pradesh, India;
2 National Institute of Pharmaceutical Education & Research (NIPER), Ahmedabad, Gujarat, India
*niperhsagarika@gmail.com

ABSTRACT
A highly sensitive, selective, reproducible, rapid and stability indicating RP-HPLC and spectrophotometric method has been developed and validated successfully for quantitative evaluation of ivabradine hydrochloride formulations. Chromatography was carried out at 25ºC on a 250 mm x 4.6 mm, 5µm, C18,  100Aº Kromasil column with phosphate buffer pH 7.4: methanol:: 35:65 and U.V. detector at λmax 286 nm. In HPLC method the retention time was about 7.4 minutes. Complete validation study for both the methods was carried out according to ICH guideline. Both methods were found to be selective, linear, accurate and precise in the specified ranges. Linearity of both the methods was achieved in the range 5 to 60 μg/ml with a correlation coefficient (r2) ≥ 0.999. The LOD and LOQ of HPLC method were 0.05 and 0.2 µg/ml, respectively. Intra-day and inter-day variability for both methods were <2% RSD. These methods were successfully used for quantification of ivabradine in drug-release studies from immediate-release tablets and controlled-release (CR) formulations.


Bachelors or Masters in Life Sciences, Pharmacy as Clinical Research Data Associate/Manager at Swanzo Care Diagnostics

Swanzo is the leading American & International patient recruitment service provider, working in 20 countries and 54 languages, and with the experience of more than 40 conditions. We run the unique EMR international patient portal, dedicated to patient recruitment. We are a global healthcare and clinical research company dealing into Healthcare, Diagnostics, Clinical site development, Patient recruitment, enrollment and their treatment. Swanzo diagnostics serve as a bridge between patient and healthcare providers. We bring treatment to patients at reasonable cost by the selected doctors well recognized and approved to be a global healthcare provider.

Post: Clinical Research Data Associate/Manager


Opportunity for Bachelor's degree in Accounting as Clinical Budget Analyst in Swanzo Care Diagnostics

Swanzo is the leading American & International patient recruitment service provider, working in 20 countries and 54 languages, and with the experience of more than 40 conditions. We run the unique EMR international patient portal, dedicated to patient recruitment. We are a global healthcare and clinical research company dealing into Healthcare, Diagnostics, Clinical site development, Patient recruitment, enrollment and their treatment. Swanzo diagnostics serve as a bridge between patient and healthcare providers. We bring treatment to patients at reasonable cost by the selected doctors well recognized and approved to be a global healthcare provider.

Post: Clinical Budget Analyst


Work in Swanzo Care for the post of Lab Technician

Swanzo is the leading American & International patient recruitment service provider, working in 20 countries and 54 languages, and with the experience of more than 40 conditions. We run the unique EMR international patient portal, dedicated to patient recruitment. We are a global healthcare and clinical research company dealing into Healthcare, Diagnostics, Clinical site development, Patient recruitment, enrollment and their treatment. Swanzo diagnostics serve as a bridge between patient and healthcare providers. We bring treatment to patients at reasonable cost by the selected doctors well recognized and approved to be a global healthcare provider.

Post: Lab Technician


Job for Pharmacists, Junior Pharmacists (42 posts) in Central Medical Services Society | location in 21 cities of India - Govt job

Central Medical Services Society, a Central Procurement Agency under Department of Health & Family Welfare, has been set up registered under Societies Registration Act, XXI of 1860 to procure and distribute health sector goods to the State Governments. The Society is looking for following warehouse staff at each of 21 locations:

Post: Pharmacist, Junior Pharmacist


Walk in for Senior Research Fellow in National Institute of Occupational Health

The following post is to be filled up under time bound research project entitled “Effect of Indoor Air Pollution on Women and Children in India” sponsored by ICMR at National Institute of Occupational Health, Ahmedabad, on contractual basis. The post is purely temporary, adhoc & contractual basis and co-terminus with the project:

Post: Senior Research Fellow (One – Reserved for SC)


Career opportunity for CRA 1 / CRA 2 / Senior CRA in Quintiles

Quintiles is the only fully integrated biopharmaceutical services company offering clinical, commercial, consulting and capital solutions worldwide. Our network of 23,000 engaged professionals in 60 countries around the globe works with an unwavering commitment to patients, safety and ethics — ensuring a higher level of healthcare for people. For our biopharmaceutical customers, we help them navigate risk and seize opportunities in an environment where change is constant.
Quintiles is consistently cited as the most favored contract research organization (CRO) in independent surveys of the bio pharma industry and was recently named “2009 CRO of the Year” by the prestigious SCRIP Awards.

Post: CRA 1 / CRA 2 / Sr CRA ( Bangalore / Mumbai / Delhi )-1407480


Opening for Medical Representative in Trexgen Pharmaceuticals | 10 Posts

We, Trexgen Pharmaceuticals Pvt. Ltd, are an emerging pharmaceutical company based in India’s vibrant pharmaceutical hub, Ahmedabad, in the state of Gujarat. Wemarket world-class quality Generic, Branded Generic and Over-the-Counter (OTC) products. Our company is driven by innovation and our business philosophy is to deliver quality pharmaceutical products to our customers and delivervalues to our stakeholders. With a dynamic team of highly experienced pharmaceutical professionals, we continue to strive toprovide quality pharmaceutical products at affordable prices to all our patients.

Post: Medical Representative


FORMULATION AND EVALUATION OF FAST DISSOLVING FILMS OF RIZATRIPTAN BENZOATE

ABOUT AUTHORS:
*P. Bhatt, M. Patel
Department of Pharma. Technology,
L.J. Institute of Pharmacy, Ahmedabad, Gujarat, India
bhatt_pari@ymail.com

ABSTRACT:
Rizatriptan benzoateis an anti migraine drug. The therapeutic activity of the drug can most likely be attributed to agonist effects at 5-HT1B/1D receptors. It is well absorbed from the gastrointestinal tract, but its oral bioavailability is low (45%) due to first-pass metabolism which makes it an ideal candidate for rapid release drug delivery system. Hence, an attempt was made to prepare and evaluate fast dissolving oral films containing Rizatriptan benzoate as a model drug by solvent casting method using hydrophilic polymers. Various formulations were developed with varying concentration of polymers like HPMC, PVA, PVP K30, Xanthan gum, Guar gum. Citric acid was used as a saliva stimulating agent and Propylene glycol as a plasticizer. The prepared oral films were evaluated for their physicochemical and mechanical parameters such as Physical appearance, surface pH, thickness uniformity, disintegration time, drug content uniformity, folding endurance, tensile strength, percentage elongation, in-vitro drug release. In-vitro release rate of Rizatriptan benzoate was studied in simulated saliva fluid (pH 6.8). From prepared formulations, the optimized plasticizer and polymer combination was selected and 32 factorial design was applied. On basis of factorial design, RSM and contour plots were applied. From factorial design batches the batch with lower disintegration time and good mechanical properties is optimized. This optimized batch was studied for its stability for 1 month. PG was optimized as plasticizer. It was observed that no single polymer was able to produce the film with desired quality hence polymer combination was used. The polymer combination of HPMC E 15 & PVA was optimized. On applying factorial design to this combination, batch with polymer ratio of 1:7 (HPMC: PVA) was optimized. The formulation was found stable after 1 month.


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