Pyrazole and Its Biological Activity

PharmaTutor (January- 2014)
ISSN: 2347 - 7881

Received On: 29/11/2013; Accepted On: 07/12/2013; Published On: 15/01/2014

About Authors:
Vishwanadham Yerragunta^*1, DuggiSuman¹, Kumara swamy¹, V.Anusha¹, Pratima Patil¹, M. Naresh²
Department of Pharmaceutical Chemistry,¹ Malla Reddy College of Pharmacy,
Maisammaguda, Secunderabad-500014, A.P.²Bharath Institute of Technology Pharmacy-Ibrahimpatnam, AP.

ABSTRACT: The aim of this review is to provide an overview of diverse pharmacological activities of pyrazole moiety. Pyrazole are well known and important nitrogen containing 5-membered heterocyclic compounds and various methods have been worked out for their synthesis. Pyrazole chemically known as 1, 2-diazole has become a popular topic due to its manifold uses. Numerous pyrazole derivatives have been found to possess a broad spectrum of biological activities, which stimulated the research activity in this field. Pyrazoles and its derivatives represent one of the most active classes of compounds, which possess wide range of biological activities like anti-bacterial, anti-convulsant, analgesic, anti-microbial, anti-inflammatory, ant diabetic, sedative anti-rheumatic, anticancer, and anti-tubercular activities. The purpose of this review was to collate literature work reported by researchers onpyrazole for their various pharmacological activities and also reported recent efforts made on this moiety.

How to cite this article: V Yerragunta, D Suman, K swamy, V Anusha, P Patil, M Naresh, Pyrazole and Its Biological Activity, PharmaTutor, 2014, 2(1), 40-48

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