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POLYELECTROLYTES: AS A DRUG DELIVERY SYSTEM

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ABOUT AUTHORS:
Surya Pratap Singh
*, Meenakshi Sahetya1, Mahaveer Prasad khichi1*, Yogesh Yaduwanshi2
1
Department of pharmaceutics, Kota college of pharmacy
2
Department of pharmacology, Kota college of pharmacy,
Rajasthan, India
*sp.kota91@gmail.com

ABSTRACT
The purpose of this paper is to focus on drug delivery system developing by such polyelectrolytes and most focused on targeting of  drugs to specific sites have aroused as revolution in pharmaceutical  field, thereby, giving rise to drug  delivery systems. Polymers have gained much importance indrug delivery especially those which respond in some desired way to change in pH, temperature, electric or magnetic field. For this reason they are very frequently and extensively used as excipients in design and advancement of controlled and/or sustained release products. The scope of polymers used in dosage form design can be increased by several approaches such as modification of their chemical structure, by combining different polymers in physical mixtures or by formation of polymer-polymer associations such as polyelectrolyte complexes.


UV-VISIBLE SPECTROSCOPY: AN OVERVIEW

ABOUT AUTHORS:
Kambham Venkateswarlu1*, N.Devanna2, Haritha Arikeri3, M.Shahinaz Farihath4
1,4M.Pharm Scholar, Department Of Pharmaceutics,
2Director Of JNTUA-Otri,
3M.Pharm Scholar, Department Of Pharmaceutical Analysis
JNTUA-Oil Technological Research Institute,
Beside Collector Office, Anantapur, Anantapur District, Andhra Pradesh, India. Pin Code: 515001
*k.v.reddy9441701016@gmail.com

ABSTRACT:
Spectroscopy is often used in physical and analytical chemistry for the identification of substances through the spectrum emitted from or absorbed by them. Spectroscopy is also heavily used in astronomy and remote sensing. Most large telescopes have spectrometers, which are used either to measure the chemical composition and physical properties of astronomical objects or to measure their velocities from the Doppler Shift of their spectral lines.
UV-Visible spectroscopy is a form of Absorption spectroscopy. Absorption spectroscopy in the UV-Visible region is to be one of the oldest and most frequently employed technique in pharmaceutical analysis for qualitative, quantitative and structural analysis of a substance in solution. The substance is analyzed by studying the spectrum produced by it due to absorption of certain wavelengths of UV-Visible light.
Spectroscopically, visible light behaves in a similar way as UV light. Hence, the techniques of UV spectroscopy and Visible spectroscopy are studied together.


WATERMELON (Citrullus lanatus): A REVIEW

About Authors:
Kambham Venkateswarlu1*, N.Devanna2, Gurrapu Lalitha3, Revanuru Sukanya4
1M.Pharm Scholar, Department Of Pharmaceutics,
2Director Of JNTUA-Otri,
3,4M.Pharm Scholar, Department Of Pharmaceutical Analysis
JNTUA-Oil Technological Research Institute,
Beside Collector Office, Anantapur, Anantapur District, Andhra Pradesh, India. Pin Code: 515001
k.v.reddy9441701016@gmail.com

Abstract:
The aim of this review is to provide information about nutritional values, what are the special considerations should take while harvesting, and world production of Watermelon fruit. Watermelon is an ancient fruit. The ancestors of the watermelon called the Tsamma melon, which are still found in the Kalahari Desert even today. This review alo gives the information about what are the constituents present in the Watermelon fruit.


A COMPLETE REVIEW ON NUCLEAR MAGNETIC RESONANCE (NMR)

ABOUT AUTHORS:
*Md. JahaSultana, P. Vijaya Sri, G.Alekhya, S.VenkateswaraRao, Chaitanya PrasadMeher
Department Of Pharmaceutical Analysis
Vijaya Institute of Pharmaceutical Sciences For Women
Enikepadu, Vijayawada-521108, Andhra Pradesh, India
sohnivya786@gmail.com

ABSTRACT:
Over a past decades, nuclear magnetic resonance (NMR) has progressed rapidly in improvement of experimental method and development of novel approaches. NMR is a research technique that exploits the magnetic properties of certain atomic nuclei. Of all the spectroscopy methods, NMR is the only one of which a complete analysis and interpretation of the entire spectrum is normally excepted. Although larger amounts of samples are needed when compared with mass spectroscopy, NMR is non-destructive and with modern instruments good data may be obtained from samples weighing less than a milligram. In this review a brief introduction to the NMR is given which includes instrumentation, parameters influencing NMR and applications.


REVIEW ON ATHEROSCLEROSIS

About Authors:
Kambham Venkateswarlu1*, N.Devanna2, C.Vanajakshi3, Kottamasi Vijaya Bhaskar4
1M.Pharm Scholar, Department Of Pharmaceutics,
2Director Of Jntua-Otri,
3M.Pharm Scholar, Department Of Pharmaceutics,
4M.Pharm Scholar, Department Of Pharmacology,
JNTUA-Oil Technological Research Institute,
Beside Collector Office, Anantapur, Anantapur District, Andhra Pradesh, India. Pin Code: 515001
k.v.reddy9441701016@gmail.com

Abstract:
This review gives the information about what are the causes, symptoms and treatment of atherosclerosis. Atherosclerosis or arteriosclerosis is a slow and progressive building up of plaque, fatty substances, cholesterol, cellular waste products, calcium and fibrin in the inner lining of an artery. This building up of plaque may lead to thickening of the arteries, subsequently blocking the blood flow either partially of totally in an artery.


FAST DISSOLVING TABLETS: A REVIEW

About Authors:
Kambham Venkateswarlu*, Kutagulla Ashna, Nandamuri Manideepika, Shaik Shaheena Parveen, M.G.Vasantharekha
M.Pharm Scholar, Department Of Pharmaceutics,
JNTUA-Oil Technological Research Institute,
Beside Collector Office, Anantapur, Anantapur District, Andhra Pradesh, India
k.v.reddy9441701016@gmail.com

Abstract:
A tablet is a pharmaceutical dosage form. It comprises a mixture of active substances and excipients, usually in powder form, pressed or compacted from a powder into a solid dose. The excipients can include diluents, binders or granulating agents, glidants (flow aids) and lubricants to ensure efficient tableting; disintegrants to promote tablet break-up in the digestive tract; sweeteners or flavors to enhance taste; pigments to make the tablets visually attractive. A polymer coating is often is often applied to make the tablet smoother and easier to swallow, to control the release rate of the active ingredients, to make it more resistant to the environment or to enhance the tablet’s appearance.

These FDTs will give the better merits when compared to existing conventional dosage forms. This system has a better compliance in the case of geriatrics and pediatrics.


PYRAZOLE AND ITS BIOLOGICAL ACTIVITY

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ABOUT AUTHORS:
Vishwanadham Yerragunta*1, Duggi.Suman1, Kumara swamy1, V.Anusha1, Pratima Patil1, M. Naresh2
Department of Pharmaceutical Chemistry,
1Malla Reddy College of Pharmacy, Maisammaguda, Secunderabad-500014, A.P.
2Bharath Institute of Technology Pharmacy-Ibrahimpatnam, AP.
*vishwanadham.y@gmail.com

ABSTRACT:
The aim of this review is to provide an overview of diverse pharmacological activities of pyrazole moiety. Pyrazole are well known and important nitrogen containing 5-membered heterocyclic compounds and various methods have been worked out for their synthesis. Pyrazole chemically known as 1, 2-diazole has become a popular topic due to its manifold uses. Numerous pyrazole derivatives have been found to possess a broad spectrum of biological activities, which stimulated the research activity in this field. Pyrazoles and its derivatives represent one of the most active classes of compounds, which possess wide range of biological activities like anti-bacterial, anti-convulsant, analgesic, anti-microbial, anti-inflammatory, ant diabetic, sedative anti-rheumatic, anticancer, and anti-tubercular activities. The purpose of this review was to collate literature work reported by researchers on pyrazole for their various pharmacological activities and also reported recent efforts made on this moiety.


REITERS SYNDROME- A FORM OF REACTIVE ARTHRITIS

ABOUT AUTHORS:
Jyotirmoyee Patnaik
Kanak Manjari Institute of pharmaceutical Sciences.
Rourkela, Orissa
patnaik.jyotirmoyee@gmail.com

ABSTRACT:
Reactive arthritis, formerly referred to as Reiter's syndrome, is a form of arthritis that affects the joints, eyes, urethra and skin. The disease is recognized by various symptoms in different organs of the body that may or may not appear at the same time. Also one form of reactive arthritis is characterized by a triad of arthritis, nongonococcal urethritis, and conjunctivitis, and by lesions of the skin and mucosal surfaces.


ACTIVITY OF CHALCONE AND ITS DERIVATIVES - A REVIEW

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About Authors:
Umakant Sahu1,2, Nrusingha Charan Panda2, B.V.V Ravikumar2, Anjan Kumar2
1Drugs testing laboratory avam anusandhan Kendra, First Floor, Govt. Ayurvedic College Hospital Building, Ayurvedic College Campus, G.E. Road Raipur, Chhattisgarh- 492010
2Department of Pharmaceutical Chemistry, Roland Institute of Pharmaceutical Sciences, Berhampur, Orissa-760010, India
uksahu28@gmail.com

Abstract
Chalcones considered as the precursor of flavonoids and isoflavonoids abundantly found in plants, and have also been shown to display a diverse array of pharmacological activities. This review is complementary to earlier reviews and covers more recent report of antimicrobial activity of chalcones as well as its important role as an intermediate for the synthesis of different synthetic molecules. The enone linkage presents in basic structure play crucial role for the activity of chalcone and chalcone derivatives. The members of the chalcone and flavonoid family have attracted a great deal of interest due to it has showed diffent activity as antibacterial, antifungal, anti-inflammatory, antihyperglycemic anti HIV and anticancer pharmacological activity. Recently a molecule of chalcone has been reported as a novel class of HIV-1 integrase inhibitors. The purpose of this review is to focus on some important pharmacological activity of the chalcone and its derivatives.


DRUG DESIGN CONCEPT IN OCULAR DRUG DELIVERY

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About Authors:
*1Ronak Patel, 2Mr. Ripal Mistry
1M.Pharm, Bhupal Nobels’ College Of Pharmacy, Udaipur 313001
2M.pharm, Indubhai Patel College Of Phaarmacy And Research Center, Dharmaj
*rk4989@gmail.com

Abstract:
Ocular administration of the drug is primarily associated with the need to treat ophthalmic diseases and is not regarded as a means for gaining systemic drug action. Major classes of drugs used are miotics, mydriatics/cyclopegics, anti-inflammatory, anti- infectives surgical adjutants and diagnostics, which are all meant for local therapy. Systemic action by using eye as a portal is generally avoided in order to prevent the risk of eye damage from high blood concentrations of drug not intended for eye. The unique anatomy, physiology and biochemistry of eye renders this organ exquisitely impervious to for gain substances thus presenting a constant challenge to the formulator to circumvent the protective barriers of the eye without causing any permanent tissue damage. Currently, the knowledge in this field is rapidly expanding, and many concept and drug delivery strategies are emerging out.