Kambham Venkateswarlu1*, N.Duganath2, Rubesh Kumar Sadasivam3, N.Devanna4
1M.Pharm Scholar, Department Of Pharmaceutics,
2Faculty Of Pharmacy, Department Of Pharmaceutical Chemistry,
3Faculty Of Pharmacy, Department Of Pharmaceutical Analysis,
4Director of JNTUA-OTRI,
JNTUA-Oil Technological Research Institute,
Beside Collector Office, Anantapur, Anantapur District, Andhra Pradesh, India. Pin Code: 515001
Diabetes mellitus is a complex metabolic syndrome that results from a heterogeneous group of disorders characterized by chronic hyperglycemia, with disturbances of carbohydrate, fat and protein metabolism resulting from the improper insulin secretion and/or inefficient insulin action and possibly by abnormally high amounts of other counter regulatory hormones such as growth hormone, sympathomimetic amines and corticosteroids.
This chronic hyperglycemia is associated with long term damage, dysfunction and failure of various organs (Multi Organ Dysfunction Synrome) leading to diabetic retinopathy, nephropathy, neuropathy and macrovascular diseases.