Kambham Venkateswarlu1*, N.Devann2, R.Venu Priya3, P.Bharath Rathna Kumar4
1M.Pharm Scholar, Department Of PharmaCEUTICS,
2Director Of JNTUA-Otri,
3Faculty Of Pharmacy, Department Of Pharmaceutics,
4Faculty Of Pharmacy, Department Of Pharmaceutical Chemistry,
JNTUA-Oil Technological Research Institute,
Beside Collector Office, Anantapur, Anantapur District, Andhra Pradesh, India.
Pin Code: 515001
Cirrhosis is defined as the histological development of regenerative nodules of liver parenchyma surrounded by fibrous septa in response to chronic liver injury. Chronic liver diseases represent a significant health problem across the globe with liver cirrhosis,an end stage consequence of fibrosis, being the major medical emergency with significant morbidity and mortality.
The exact prevalence of this life threatening disease worldwide is unknown as clinical spectrum of cirrhosis ranges from indolent, asymptomatic to complete hepatic decompensation. The progression of fibrosis to cirrhosis is lower in women than men due tothe protection offered by oestrogens. The ultimate curative option for liver cirrhosis currently is liver transplantation, which poses significant risk to the patient.