You are herePharmacology Articles
Pharmacology Articles
ANTIPYRETIC ACTIVITY OF SEED EXTRACTS OF Gynocardia Odorata roxb. IN EXPERIMENTAL ANIMALS
About Authors:
Urmila moyal*, Ram garg
NIMS Institute of Pharmacy, NIMS University,
Shobha Nagar, Jaipur (Rajasthan)
*urmilamoyal@gmail.com
Abstract:
The study was designed to evaluate antidiabetic activity of ethanolic and aqueous seed extracts of Gynocardia Odorata in
- Brewer’s yeast induced pyrexia in rats.
- TAB vaccine-induced pyrexia in rabbits.
The seeds were collected, authenticated and shade dried. Shade dried seeds were then grinded into coarse powder and processed for further studies. Ethanolic and aqueous extracts were prepared and the phytochemical screening was performed. Ethanolic and aqueous both extracts were evaluated for the antipyretic activity by Brewer’s yeast induced pyrexia in rats and TAB vaccine-induced pyrexia in rabbits. Both the extracts showed the significant antipyretic activity but the maximum antipyretic activity by aqueous extract of Gynocardia odorata roxb.seeds. From study we concluded that both ethanolic and aqueous, seed extracts of Gynocardia odorata have antipyretic activity, but the aqueous extract of Gynocardia odorata showed more significance then ethanolic extract.
A REVIEW ON DESCRIPTION AND COMPLETE TREATMENT OF TUBERCULOSIS (ALL TYPES)
About Author:
Rahul Singh
M.PHARMA (Pharmaceutics)
Shri Rawatpura Sarkar Institute Of Pharmacy
Kumhari, Distt-Durg, Chhatishgarh, India
rahulbaba92@yahoo.in
ABSTRACT:-
Tuberculosis (abbreviated TB for tubercle bacillus or Tuberculosis) is a common and often deadly infectious disease caused by mycobacteria. In humans, Mycobacterium tuberculosis is the primary causative bacterium although other mycobacteria such as Mycobacterium bovis, Mycobacterium africanum, Mycobacterium canetti, and Mycobacterium microti are also causes. Tuberculosis usually attacks the lungs (as pulmonary TB) but can also affect the central nervous system, the lymphatic system, the circulatory system, the genitourinary system, the gastrointestinal system, bones, joints, and even the skin.
THE ROLE OF COX-2 INHIBITORS IN HUMAN CANCER PREVENTION AND OTHER NOVEL TARGETS - A RECENT REVIEW
About Authors:
Lohithasu Duppala*1, Madhu priya Damuluri1, Anil kumar vadda2
1GITAM Institute of Pharmacy, GITAM University, Pharmaceutics, visakhapatnam, Andhra Pradesh, India-530045.
2AVANTHI Institute of pharmaceutical sciences, pharmacology, visakhapatnam, Andhra Pradesh, India-530045.
*lohithasu@gmail.com, anilkumar.vadda@gmail.com
ABSTRACT:
COX-2 (Cyclooxygenase-2) is a selective inhibitor of non-steroidal anti-inflammatory drug (NSAID). Cyclooxygenase -2, an enzyme responsible for inflammation and pain. Celecoxib, Rofecoxib, valdecoxib, Parecoxib are class of COX-2 inhibiting drugs. COX-2 inhibitors have been revealed to reduce the occurrence of cancers and pre-cancerous growths. Celecoxib, cox-2 inhibitor isused to prevention of polyp formation in Familial Adenomatous Polyposis (FAP). COX-2 inhibitors like celecoxib, Rofecoxib, valdecoxib, Parecoxibare currently being studied in cancer treatment and other targets. This review highlights the COX-2 inhibitors with special emphasis on their role in various kinds of cancer prevention and other targeted therapy. COX-2 inhibitors in cancer chemotherapy and neurological diseases like Parkinson and Alzheimer’s diseases still continues to attract researches on the development of COX-2 inhibitors.
PHARMACOLOGICAL EVALUATION OF ETHANOLIC EXTRACT OF EMBELIA RIBES: (VIDANGA) FRUIT IN EXPERIMENTAL ANIMAL MODELS
About Authors:
Saritha.A.Surendran*, Asa Samuel
*St. James College of Pharmaceutical Sciences,
Chalakudy, Kerala
*sarithaasurendran@gmail.com
ABSTRACT
Analgesics are the drug that selectively relieves pain by acting in the CNS or peripheral pain mechanism without significantly altering consciousness. They are classified into centrally acting analgesics and peripherally acting analgesics. Embelia ribes seeds was collected and extracted by continous hot percolation process using ethanol. Phytochemical analysis of the extract was preformed, screened and compared the analgesic activity of the extract with Pentazocine. Animal treated with ethanolic extract of Embelia ribes was showed an increased reaction time compared to control group. Ethanolic extract was showed significant reduction in algesia when compared with pentazocin.
TREATMENT OF MALARIA IN PAEDITRICS: A REVIEW
About Author:
Kambham Venkateswarlu
Final Year Graduate Student
Sri Lakshmi Narasimha College of Pharmacy,
Palluru, Chottoor-517132, Andhra Pradesh, India.
k.v.reddy9441701016@gmail.com
ABSTRACT:
Malaria is an infectious disease caused by a parasite (plasmodium) which is transmitted from human by the bite of infected female Anopheles mosquitoes. Four species of the parasite plasmodium are responsible for Malaria in humans: Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, Plasmodium falciparum.
This disease cause a nearly 300 to 400 million clinical episodes of malaria occur worldwide, out of which 1.5 to 2 million die every year. So this is also a most dangerous disease in children. This review reveals the treatment of malaria in paediatrics.
A CLINICAL STUDY ON THERAPEUTIC MANAGEMENT OF VIRAL HEPATITIS-A IN PAEDITRICS
About Author:
Kambham Venkateswarlu
1-Final Year Graduate Student
Sri Lakshmi Narasimha College of Pharmacy,
Palluru, Chottoor-517132, Andhra Pradesh, India.
k.v.reddy9441701016@gmail.com
ABSTRACT:
Hepatitis is a general term meaning inflammation of the liver and can be caused by a variety of different viruses such as hepatitis-A, B, C, D, and E. Since the development of jaundice is a characteristic of liver disease, a correct diagnosis can only be made by testing patient’s sera for the presence of specific anti-viral antibiotics. Transmission of HAV is typically by the faecal, oral route. Hepatitis A was formerly called infectious hepatitis, Epidemic hepatitis, Epidemic jaundice, Catarrhal jaundice, type A hepatitis, HA.
Biosensor for HIV Diagnosis at All Stages of Infection- A Nano Idea
About Authors:
Dhanya V C
Kasturba medical college, Manipal University
Indian Veterinary Research Institute
dhanya285@gmail.com
INTRODUCTION:
A biosensor is a device that uses specific biochemical reactions mediated by isolated enzymes, immunosystems, tissues, organelles or whole cells to detect chemical compounds usually by electrical, thermal or optical signals (1). Or in other words, Sensor that integrates a biological element with a physiochemical transducer to produce an electronic signal proportional to a single analyte which is then conveyed to a detector.
REVIEW ON PROSTATE CANCER THERAPY
About Authors:
Kambham Venkateswarlu1*, G.Sujatha2
1Graduate Student
2Department of Pharmaceutical Chemistry
Sri Lakshmi Narasimha College of Pharmacy, Palluru,
Chittoor District, Andhra Pradesh-517132, India.
*k.v.reddy9441701016@gmail.com
I. INTRODUCTION
1.1. WHAT IS PROSTATE CANCER?
Prostate cancer is the most common type of cancer in men and is the second leading cause of cancer-related deaths in men worldwide. It is a disease of the prostate gland in which malignant cells form in the tissues of the prostate and multiply out of control. These cells often metastasize to other parts of the body, like the rectum, the bladder and especially, the bones and the lymph nodes. It generally arises near the surface of the gland so that it can be diagnosed easily by digital rectal examination (DRE). Depending on the extent of metastasis, the prostate cancer tissue has been graded using the Gleason System into a score of 2 to 10 or into four stages I-IV (or, A-D), indicating the likelihood of spreading of the disease to other parts of the body.
Although several types of cells are found in the prostate, over 99% of the cancers occur in the gland cells only (cells which make the prostate fluid which is added to the semen). Such type of cancer is termed as adenocarcinoma. The region of prostate gland where the adenocarcinoma is most common is the peripheral zone. Other types of cancer can also start in the prostate gland, including sarcomas (like leiomyosarcoma and rhabdomyosarcoma), small cell carcinomas, and transitional cell carcinomas, although they are extremely rare. Generally, the cancer grows and spreads very slowly. Early prostate cancer most often causes no symptoms. Sometimes, however there are signs and symptoms very close to those of benign prostatic hyperplasia (BPH).
BRUGADA SYNDROME: DIAGNOSIS, ORIGIN, RELATION WITH OTHER SYNDROMES
About Author:
Kambham venkateswarlu
Graduate student
Sri Lakshmi Narasimha College of Pharmacy, Palluru,
Chittoor District, Andhra Pradesh-517132, India.
k.v.reddy9441701016@gmail.com
ABSTRACT:
Brugada syndrome is a genetic cause of sudden cardiac arrest characterized by abnormal electrocardiographic (ECG) pattern in the right precordial leads either at rest or after provocation. In this condition, sudden death may occur due to polymorphic ventricular tachycardia or ventricular fibrillation. In approximately 30% of patients, sudden cardiac arrest is the initial clinical manifestation of Brugada syndrome.
BRUGADA SYNDROME: ETIOLOGY AND GENETICS, INCIDENCE, PATHOLOGICAL FINDINGS, CLINICAL MANIFESTATIONS
About Author:
Kambham Venkateswarlu
Graduate Student
Sri Lakshmi Narasimha College of Pharmacy,
Palluru, Chittoor District, Andhra Pradesh-517132, India.
k.v.reddy9441701016@gmail.com
ABSTRACT:
This is an inherited arrhythmia that causes the bottom chambers of the heart (the ventricles) to beat so fast that they can prevent the blood from circulating efficiently in the body. When this situation occurs (called ventricular fibrillation), the individual will faint and may die in a few minutes if the heart is not reset. While this is a disease that usually affects people in their 30's, it has actually been described at all ages. So it is important to screen everybody in a family. Not everybody who has the disease will have arrhythmias. However, we cannot know yet who will be OK and who will have problems. If you have had fainting spells related to Brugada syndrome, our experience indicates that you are at very high risk of having them again.
FIND MORE ARTICLES
