Pharmacognosy Articles

EVALUATION OF ANTIBACTERIAL ACTIVITY OF MOMORDICA CHARANTIA

ABOUT AUTHORS
Deepak Ku. Birla*
Shri Bherulal Pharmacy Institute
Indore, Madhya Pradesh, India
deepakbirla7@gmail.com

ABSTRACT
Momordica Charantia is the widely consumed fruit in India. The seeds, fruit, leaves, and root of the plant have been used in traditional medicine for microbial infections, sluggish digestion and intestinal gas, menstrual stimulation, wound healing, inflammation, fever reduction, hypertension and have many significant other medicinal effects. Various phytochemicals present in leaves are extracted using soxhelt apparatus with different solvents. The aim of the study is to assess the antibacterial activity and to determine the zone of inhibition of extracts on some bacterial strains. The antibacterial activity was checked against different human pathogens. The antibacterial activity was determined in the extracts using Disc diffusion method. The present study discusses antibacterial activity of Momordica Charantia extracts. Antibacterial activity was tested against (Pseudomonas aureogenosa, Staphylococcus aureus, Staphylococcus epidermis, Shigella flexineri, Bacillus substilis & E.Coli.). The results showed that the remarkable inhibition of the bacterial growth was shown against the tested organisms.


COMPARATIVE STUDY OF PHARMACOGNOSTICAL AND PRELIMINARY PHYTOCHEMICAL INVESTIGATION OF CURCUMA LONGA LEAVES AND RHIZOMES

ABOUT AUTHORS
Seema*, Parminderjit Kaur
Department of Pharmacy,
Rayat Bahra Institute of Pharmacy, Hoshiarpur, Punjab, India
*seemakumar2125@gmail.com

ABSTRACT
Turmeric (Curcuma longa) is a perennial herb, belonging to family Zingiberaceae. The rhizomes and leaves of turmeric were extracted separately with ethanol by Soxhlet extraction and the percentage yield of rhizomes and leaves of Turmeric was 12% and 17% yield respectively. The extract of turmeric rhizomes and leaves can increase the bile flow, offer protection of the gall bladder and also the leaf extract possess anticancer properties. The present study was focused on the isolation of curcuminoids by thin layer chromatography using chloroform: ethanol: glacial acetic acid in a ratio of 95: 5: 1. From TLC the better resolution of Rf value was observed in rhizomes at 0.8, 0.66, 0.51 as Curcumin, Demethoxycurcumin, Bisdemethoxycurcumin respectively whereas Rf value of leaves was 0.42 as Bisdemethoxycurcumin, when visualized under 366nm under bright yellow fluorescent. The phytochemical screening of leaf extracts showed the presence of flavonoids, cardiac glycosides and phenols. The ash value of turmeric rhizomes and leaves was 3.33% and 6.67%, acid insoluble value was 1.3% and 2% and water insoluble value was 13.3% 1nd 16.67% respectively. The moisture content of rhizomes and leaves of turmeric in IR- Moisture balance was found to be 0.93 and 0.30 whereas in Tray Drier the moisture balance was 0.46 and 0.27 respectively while the melting point was observed as 160-1630C and 116-1200C respectively which resembles the report of literature (IP, 2007).


QUANTITATIVE ESTIMATION OF SECONDARY METABOLITE AND INHIBITORY EFFECT OF AZIMA TETRACANTHA LEAVE EXTRACT AGAINST CANDIDA ALBICANS

ABOUT AUTHORS
SANDHIYA.V*1, KAVITHA.C2
1 Department of Pharmaceutics, C.L.Baid metha College Of Pharmacy, Thoraipakkam, Chennai, India
2 Department of Pharmacognosy, C.L.Baid Metha College Of Pharmacy, Thoraipakkam, Chennai, India
*sandhiyavaithi@gmail.com

ABSTRACT
The leaves of Azima tetracantha belongs to salvadoraceae family, commonly known as “mulluchangu” in tamil, it is a best known medicinal plant from ancient period. The plant has reported for many pharmacological action such as antifungal, antibacterial, hepatoprotective, anti inflammatory, anti ulcer, anti arthritic, hypolipidemia etc. The present study was investigated about the characteristics, quantitative estimation and antifungal activity of Azima tetracantha leave in different solvents extract (hexane, chloroform, ethanol, ethyl acetate and water) successfully. In quantitative estimation the leaves of Azima tetracantha shows 48.4 % yield of carbohydrate in water extract, 21%  yield of phenol in ethanol extract and 24%  in ethyl acetate extract and 19% yield of tannin in ethanol extract. In antifungal activity of Azima tetracantha leave two standard drugs are used such as clotrimazole (10 mcg/m1 as standard-1) and ketaconazole (10 mcg/ml as standard -2). The antifungal activity was studied for all extracts in a concentration of 100 mcg/ml, 200 mcg/ml and 400mcg/ml against Candida albicans and Aspergillus niger. The Ethanol extract of a leave of Azima tetracantha in increasing concentration shows prominent activity against Candida albicans compared to other extract. The Hexane, Chloroform and Water extracts of a leave of Azima tetracantha shows moderate activity against Candida albicans compared to ethyl acetate extract. The Ethyl acetate extract shows slight activity against Candida albican scompare to other extracts. There was no activity was observed for various extracts of Azima tetacantha against Aspergillus niger.


PHARMACOGNOSTICAL STUDIES FOR STANDARDISATION OF A MEDICINAL SPICE, THE FRUIT OF ILLICIUM VERUM HOOK. F.

ABOUT AUTHORS
M. A. Rashid*, R. H. Zuberi

Pharmacognosy Section
Regional Research Institute of Unani Medicine (RRIUM),
Aligarh, UP, India
* marashid212@gmail.com

ABSTRACT
The fruit of Illicium verum Hook. f. of family Magnoliaceae has been utilized therapeutically as medicine as well as a spice. It is used to relieve a number of human ailments, owing to its properties as carminative, stimulant and appetizer. In order to set the quality standards, the market sample of the drug has been identified and standardized on the basis of Pharmacopoeial parameters, such as salient macro and microscopic characters, ash values, solubility, successive extractive values, thin layer chromatographic evaluations and U.V. spectroscopic analysis. Besides qualitative and quantitative estimations, fluorescence analysis of powdered drug has also been carried out in order to set standards for the crude drug.


REVIEW ON: INDIAN MEDICINAL PLANTS HAVING ANTICANCER PROPERTY

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ABOUT AUTHORS
Nandu Kayande*, Rakesh Patel
Department of Pharmacy,
OPJS University, Churu, Rajasthan, India
* nandu_kayande@rediffmail.com

ABSTRACT
The traditional Indian medicine - Ayurveda, describes various herbs with anticancer as well as antioxidant properties. Various plant products have been used in treatment of cancer over the years. India is a peninsula of herbal hub, in which ayurvedics system of medicine has flourished as an enlightment in the field of Medicine. Currently medicinal plants have become the paramount source of drug discovery in research for treating diverse form of diseases including Cancer. In this review ayurvedas classical literature and evidence based research data were emphasized to explore the ayurvedic medicinal plants with potent anticancer activity.


A REVIEW ON: PHYSICOCHEMICAL EVALUATION OF AYURVEDIC MINERAL DRUG TANKAN BHASMA

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ABOUT AUTHORS:
*Shaikh S.M., Doijad R.C., Shete A.S., Sankpal P.S.
Shree Santkrupa College of Pharmacy,
Ghogaon, Karad Maharashtra 415111 (India)
*sabirmshaikh17@gmail.com

ABSTRACT:
Tankan bhasma which has been used since very long time in Ayurveda. Tankan bhasma purification is done by the mand agni. Evaluation of physic-chemical property of Tankan bhasma. We are studing toxicological study of Tankan (Borax). Toxicological study on eyes, skin, inhalation, ingesion, carcinogenicity, reproductive or developmental, target organs, also signs and symptoms of exposure. We are studied on the first aid treatment if hazards due to contacts with eyes, Ingestion, and skin. Various uses of Tankan (Borax) bhasma we are studying. Also we are studying the analytical evaluations. Such as Tankan (Borax) bhasma evaluation containing moisture content, organic contain, Nishchandratva, Nishchandratva, Varitaratvam, Rekhapurnatvam, Unama test, Nirchandrata, Amla pariksha, Avami, Anjana Sannibha, X-ray diffraction i.e XRD study, also the Scanning Electron Microscope that is SEM, this all methods we are using for the evaluation of Tankan (Borax) bhasm.


ACTIVITIES OF AQUEOUS EXTRACTS OF MANGIFERA INDICA ON PARASITAEMIA LEVEL AND BLOOD PROFILE OF PLASMODIUM BERGHEI - INFECTED ALBINO MICE

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ABOUT AUTHORS
*Olayode, Ahmed A1; Saka, Olusola S1; Ajayi, Olusoji C2; Agbaje, Mojeed A1
1Department of Anatomy and Cell Biology, Faculty of Basic Medical Science
2Department of Pharmacognosy, Faculty of Pharmacy
Obafemi Awolowo University, Ile-Ife, Nigeria
olayodeahmed01@gmail.com

ABSTRACT
This study was carried out to assess the effect of Mangifera indica on the percentage parasitaemia and some blood parameters of Plasmodium – infected Albino mice. Forty-two male albino mice, weighing between 20 and 25 g, were used for this research. The mice were randomly assigned into six groupsA, B, C, D, E and F of seven mice each. Group A was the negative control, group B was positive control. Mice in groups C, D and E were orally administered with Mangifera indica extract (50 mg/kg, 100 mg/kg and 150 mg/kg body weight) respectively for 5 days starting from the 4th day of inoculation while mice in group F were orally administered with Artesunate for 5 days (3 mg/kg b.w on the first day and 1.5 mg/kg b.w for the next 4 days) starting from the 4th day of inoculation. Blood smears were taken every 2 days to check the parasitaemia level for 14-day post-treatment withdrawal period. The extract has a dose dependent reducing effect on the level of parasitaemia. It also showed that the increase in the rate of reticulocytosis and consequent increase in the number of red blood cells in a dose dependent manner.


COMMONLY USED MEDICINAL PLANTS IN TEHSIL PACHHAD, DISTRICT SIRMOUR, HIMACHAL PRADESH

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ABOUT AUTHORS:
Shubham Sharma*1, Monika Rana2
1Abhilashi College of Pharmacy, Mandi (H.P)
2Abhilashi University, Mandi (H.P)
Shubhamcoolsharma045@gmail.com

ABSTRACT
Himachal Pradesh is located in Western Himalaya, is a store house of medicinal plants. Most of the population lives in villages and use various plants for their basic needs such as food, fodder, wood and to treat various diseases.  The present study is carried out in district Sirmour of Himachal Pradesh, regarding the ethno medicinal plants used by the locals in their own traditional health system. This study reveals the status of ethno-medicinal plants and their importance preserved by locals of Distt Sirmour. The paper encompasses the 43 medicinal plants. These plants were collected from different villages of Sirmour Distt and information was collected from locals peoples.


TOMATO CUISINES: A DELECTABLE REJOINDER TO THREAT OF CHRONIC AILMENTS?

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ABOUT AUTHORS:
Vikram S. Chauhan1*, Bina Rani2, Priyanka Bishnoi3, Raaz K. Maheshwari3

1
Department of Botany, SBRM Govt PG College, Nagaur, Rajasthan, India
2Department of Engineering chemistry & Environmental Engineering, Poornima College of Engineering, Jaipur, India
3Department of Chemistry, SBRM Government PG College, Nagaur, Rajasthan, India
*vikkysingh2000@yahoo.com; rkmgreenchem.jaipur@gmail.com

ABSTRACT
With the advent of modern times, stress and pollution have led to major effect on rise of death toll due to chronic diseases. Such diseases are major cause of concern for the medical society. Lycopene, a carotenoid pigment found in tomatoes and its products has antioxidant properties due to the presence of numerous double bonds. Increased consumption of lycopene containing diet has been proposed to offer a protection against many types of cancers and cardio-vascular diseases. Its potential role as nutraceutical has been suggested in many studies. The present review deals with fundamental biochemistry, bio-availability and benefits of lycopene rich diet and its relation with some chronic diseases like various forms of cancers and cardiovascular diseases.


STUDY ON AGARWOOD (AQUILARIA MALACCENSIS) TO EVALUATE ANTIBACTERIAL AND ANTIOXIDANT ACTIVITIES OF N – HEXANE, CHLOROFORM AND ETHYL ACETATE EXTRACTS

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ABOUT AUTHOR:
Yesmin Begum
Department of Pharmacy,
Southeast University, Banani, Dhaka
yesumyta@gmail.com

ABSTRACT
The present research aims to investigate the antibacterial and antioxidant activities of different leaf extracts of Aquillaria malaccensis. Antibacterial tests were done by Disc diffusion method using Kanamycin as standard. The chloroform extract showed good antibacterial activity against Shigella boydii and Escherichia coli with 19 mm and 17 mm zone of inhibition respectively. All other extracts showed mild to moderate antibacterial activity against other bacteria with 7 – 16mm zone of inhibition. The antioxidant activity of the extracts was determined by using DPPH spectrophotometrically and ascorbic acid was used as standard. All three extracts showed significant antioxidant activities having IC50 value of 38.96 µg/ml, 39.63 µg/ml and 64.75 µg/ml for ethyl acetate, n –hexane and chloroform extracts respectively.


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