Alternatives to the Draize Eye Test
PharmaTutor (October- 2014)
ISSN: 2347 - 7881
(Volume 2, Issue 10)
Received On: 12/08/2014; Accepted On: 19/08/2014; Published On: 01/10/2014
AUTHORS: Bushra Shamim
Department of Pharmaceutics,
Faculty of Pharmacy,
Hamdard University, New Delhi.
Industry and regulatory bodies responsible for public health are actively assessing animal free tests to reduce the requirement for Draize testing. Draize rabbit eye irritation test developed in the 1940’s is even today the only eye toxicity test officially accepted in the OECD countries for regulatory purposes in the classification of slightly and moderately irritating chemicals. The Draize test has been widely criticized for both scientific and ethical reasons, and alternatives have been investigated for several decades. Therefore in an attempt to minimize this conflict alternative methods have been investigated. This article presents those alternative methods that are currently the most developed and the most widely used.
How to cite this article: B Shamim; Alternatives to the Draize Eye Test; PharmaTutor; 2014; 2(10); 45-57