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UPSSSC Pharmacist Main Examination Paper with Answer Key 2026

UPSSSC Pharmacist Main Examination Paper with Answer Key 2026

The Main Examination for the selection of Pharmacists, under the Commission's Advertisement No. 01-Exam/2026 (Pharmacist Main Exam (PET-2025)/02), was conducted on June 29, 2026. Subsequently, via the Commission's important notice dated July 1, 2026, the provisional answer key for the said written examination was uploaded to the Commission's website for candidates' review; furthermore, via the important notice dated July 2, 2026, a link was provided on the website to submit objections (if any) regarding the provisional answer key

1. What is a buffer solution?
Answer: A solution that resists change in pH

2. Which pair consists of a Lewis acid and a Lewis base respectively?
Answer: H⁺ and OH⁻

3. Saline cathartics produce their effect primarily by
Answer: Increasing osmotic load in the GIT (Gastrointestinal Tract)

4. Which of the following pairs of antiseptics and disinfectants is incorrectly matched?
Answer: Alcohols – Glutaraldehyde

5. Which of the following is not a function of sodium electrolyte?
Answer: Protein synthesis


6. Which of the following statements best defines acidifiers?
Answer: Inorganic chemicals that produce or become acid

7. Which of the following pair is correctly matched with cyanide poisoning treatment?
Answer: Sodium nitrite and sodium thiosulfate

8. Which of the following is used in lead poisoning?
Answer: Sodium calcium edetate

9. Which radioisotope is used in fibrinogen scan?
Answer: Iodine-125

10. Which radioisotope is used for both radiotherapy and sterilization of heat labile substances?
Answer: Cobalt-60

11. The major vitamin present in Amla is
Answer: Vitamin C

12. In petroleum layer, Gambier fluorescin test gives
Answer: Green fluorescence

13. The oily liquid present in Balsam of Tolu is called
Answer: Cinnamein

14. Gymnema is commonly known as
Answer: Gudmar

15. Concentrated nitric acid test on fresh Rauwolfia root produces
Answer: Red colour

16. Which alkaloid listed is used as both choleretic and laxative?
Answer: Boldine

17. Which of the following colourants is correctly matched with its source and stability?
Answer: Carmine powder – Dactylopius coccus – Precipitates below pH 4

18. Friedrich Wohler synthesized urea by heating
Answer: Ammonium cyanate

19. A six-membered ring structure of a monosaccharide is termed
Answer: Pyranose

20. Which of the following is an unbranched storage homoglycan?
Answer: Amylose

21. The C-2 carbon of triacylglycerol becomes chiral when
Answer: Acyl groups at C-1 and C-3 are different

22. Phylloquinone participates in which type of biological process in plants?
Answer: Photosynthesis

23. Vitamin E is chemically known as
Answer: α-tocopherol

24. The formation of vitamin D3 in skin is
Answer: Nonenzymatic process triggered by sunlight

25. Enzymes accelerate the rate of the reactions primarily by
Answer: Stabilizing the transition state

26. Which enzyme catalyzes the breakdown of hydrogen peroxide in biological systems?
Answer: Catalase

27. Which of the following is a regulatory protein?
Answer: Insulin

28. Which matching of vertebral feature is correct?
Answer: Lumbar – short blunt spinous process

29. A patient shows increased heart rate and contractility leading to raised blood pressure. The most likely hormones involved are
Answer: Norepinephrine and epinephrine

30. Vital capacity includes all except
Answer: Residual volume

31. Which muscle shows fascicles that spread widely and converge at a central tendon forming a triangular shape?
Answer: Pectoralis major muscle

32. Dysphagia refers to
Answer: Difficulty in swallowing

33. The time interval between infection and first appearance of signs and symptoms is called
Answer: Incubation period

34. Which of the following best represents the core components of epidemiology?
Answer: Frequency, distribution, and determinants of diseases

35. Immunity after gonorrhea infection is
Answer: No immunity

36. “Lockjaw” refers to which disease?
Answer: Tetanus

37. The term “hematophagous arthropod” refers to organisms that
Answer: Feed on blood

38. Dengue virus belongs to which group of viruses?
Answer: Flavivirus

39. Infection with poliovirus confers which type of immunity?
Answer: Permanent immunity

40. Resistance to Coronavirus infection is mainly seen in
Answer: Vaccinated people

41. Insoluble dietary fibres are mainly found in
Answer: Wheat bran and vegetables

42. According to pharmaceutical ethics, the first priority of a pharmacist is
Answer: Consumer’s health and well-being

43. In case of refilling prescriptions, the prescriber should
Answer: Guide the pharmacist with appropriate instructions

44. The Chief of the Drug Control Department of the State is a member of the Council as
Answer: Ex-officio member

45. Ceiling price is
Answer: Government fixed price

46. Medical Termination of Pregnancy Act was enacted in
Answer: 1971

47. Schedule M of the Drugs and Cosmetics Rules deals with
Answer: Good Manufacturing Practices

48. Schedule P of the Drugs and Cosmetics Rules deals with
Answer: Life period and storage of drugs

49. Receptors with no known endogenous ligand are called
Answer: Orphan receptors

50. Which is a compelling indication for diuretics?
Answer: Heart failure

51. Hearing loss with diuretics occurs only with
Answer: High ceiling diuretics

52. 5-HT₃ receptor antagonists include
Answer: Ondansetron, Granisetron

53. Which drug is not an alkylating agent?
Answer: Methotrexate

54. Open tender system is also known as
Answer: Public or unlimited tender

55. Lower price technique means
Answer: Selling products at reduced price to promote sales

56. Salesmanship is best described as
Answer: Personal contact-based selling process

57. Short term finances are generally required for
Answer: Working capital needs

58. The two main types of shares are
Answer: Preference and Equity shares

59. Drug basket method is associated with
Answer: Non-charge floor stock system

60. Unit dose dispensing system can be broadly classified into
Answer: Centralized and decentralized systems

61. Hospital formulary helps in
Answer: Preventing wastage of drugs

62. If prescriber is unaware of formulary, pharmacist should
Answer: Inform the prescriber

63. Level-I evidence in adherence studies refers to
Answer: Meta analysis of randomised controlled trials with high power

64. Drug Use Evaluation (DUE) is best described as
Answer: An ongoing, authorised and systematic quality improvement process

65. The ideal buffering pH range of an antacid is
Answer: pH 4–6

66. The World Wide Web (WWW) was invented by
Answer: Tim Berners-Lee

67. The Central Processing Unit (CPU) is also known as
Answer: Brain of the Computer

68. Which of the following is an input device?
Answer: Scanner

69. What does the ‘Refresh’ button in a browser do?
Answer: Reload the current page

70. Mobile banking requires which of the following?
Answer: Internet-enabled smartphone

71. A plotter is used to print
Answer: Large engineering drawings

72. An e-reader (like Amazon Kindle) is primarily used for
Answer: Reading e-books

73. Which of the following is an example of unsupervised learning?
Answer: K-means clustering

74. Alexa and Google Assistant are examples of
Answer: AI-powered virtual assistants

75. India’s first supercomputer was
Answer: PARAM

76. The process of cleaning and organising raw data for analysis is called
Answer: Data wrangling/cleaning

77. In MS-Word, ‘Track Changes’ feature is used for
Answer: Recording edits made to a document

78. In MS-Excel, what does the $ sign in a cell reference (e.g. $A$1) indicate?
Answer: Absolute cell reference

79. Which of the following is an advantage of e-Governance?
Answer: Provides 24/7 citizen services

80. Cryptocurrency is based on which technology?
Answer: Blockchain

81. In Uttar Pradesh one of the most important festivals for the people of Ballia is
Answer: Dadri Mela

82. Which soil type is most widely found in Uttar Pradesh?
Answer: Alluvial soil

83. Which main vegetation is commonly found in Uttar Pradesh?
Answer: Tropical deciduous forests

84. The doab region in Uttar Pradesh refers to
Answer: Land between two rivers

85. Which city of Uttar Pradesh is famous for Chikankari embroidery?
Answer: Lucknow

86. Which city is known as the ‘City of Nawabs’ in Uttar Pradesh?
Answer: Lucknow

87. Which craft of Uttar Pradesh is related to glass bangles?
Answer: Firozabad glasswork

88. Which of the following is a major center of carpet weaving in Uttar Pradesh?
Answer: Bhadohi

89. The ‘Nautanki’ of Uttar Pradesh is best described as
Answer: Folk theatre

90. Which of the following crafts of Uttar Pradesh involves brassware?
Answer: Moradabad craft

91. Which of the following statements is correct regarding Banarasi tabla style of Uttar Pradesh?
Answer: It is a percussion style associated with Hindustani music in Varanasi.

92. ‘Padmavat’ is a famous literary work written by
Answer: Malik Muhammad Jayasi

93. Amir Khusrau, associated with Uttar Pradesh, contributed mainly to which literary tradition?
Answer: Persian and Hindavi literature

94. Which of the following tourism patterns is most associated with the Braj region of Uttar Pradesh?
Answer: Pilgrimage tourism

95. Which of the following statements is correct regarding tourism in Uttar Pradesh?
Answer: Tourism in Uttar Pradesh is based on a combination of religious, cultural, and historical sites.

96. Which of the following statements is correct regarding the ecological importance of the Terai in Uttar Pradesh?
Answer: The Terai region has high biodiversity and forest resources.

97. Which of the following statements is correct regarding the Governor of Uttar Pradesh?
Answer: The Governor is appointed by the President of India.

98. Which of the following statements is correct regarding the Vidhan Sabha of Uttar Pradesh?
Answer: It is directly elected by the people.

99. Which of the following statements is correct regarding prepaid smart meters in Uttar Pradesh?
Answer: They will be used for all new electricity connections

100. Meerut Metro in Uttar Pradesh started operation in
Answer: February 2026