Karolinska Institutet is one of the world’s leading medical universities. Our vision is to advance knowledge about life and strive towards better health for all. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
Post : Doctoral (PhD) student position in signal transduction and targeted therapy in cancer
Job Description
The candidate should be able to document very good experience with the following :
• Cell culture work cell culture, cell growth and cell death assays, 3D culture models, transgenic modification of cell lines.
• RNA experiments: RT-qPCR, DNA/RNA extraction.
• Protein experiments: Western blots, immunostaining, FACS, immunoprecipitation, sample preparation to be used in animal models.
• Demonstrate ability to organize, plan and document experimental bench-work.
• Excellent communication skills and the ability to work both independently and in collaboration with colleagues in very diverse fields.
• Ability to stay on top of the relevant research field.
• Experience in scientific writing.
• Cell culture work: Generation of stable cell lines.
• RNA experiments: quantitative PCR, RNA extraction from FFPE samples. Plasmid constructions using restriction enzymes and gateway system. Experience with next-generation sequencing analysis including RNA and DNA seq, ChIPseq,
• Experience with advanced state-of-the art confocal microscopy, FRET/BRET.
• Xenopus or zebrafish experiments: Handling of these animals, microinjection techniques to eggs, and whole mount in situ hybridization.
• Previous experience in experimental application of molecular and cellular biology techniques in cancer-biomarkers discovery.
• Documented research experience within cancer signaling field.
• Experience in supervising/co-supervising students at the undergraduate level.
• Experience in scientific writing documented by scientific publications.
Candidate Profile
A) • have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
• have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
• have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*
B) Specific eligibility requirement
You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:
- Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.
Additional Information
Qualification : master degree
Location : Sweden
Industry Type : Pharma/ Healthcare/ Clinical research
End Date : 22th Sep.2022
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