Require Senior Research Scientist at Pfizer

Founded in 1849, Pfizer is the world's premier biopharmaceutical company taking new approaches to better health. We discover, develop, manufacture and deliver quality, safe and effective prescription medicines to treat and help prevent disease for both people and animals. We also partner with healthcare providers, governments and local communities around the world to expand access to our medicines and to provide better quality health care and health system support.

Post : Senior Research Scientist Drug Product Design, Biopharmaceutics

Job Description
• Be the catalyst to advance the utilization of solution and solid-state thermodynamic principles governing physical phenomenon in drug product design and development with a focus on biopharmaceutics attributes of the molecule and drug delivery system
• Utilize and apply the principles of physics and physical chemistry to characterize and understand the thermodynamics and kinetic processes of drug species in solution to enable the design of a variety of drug delivery systems and predict the in vitro & in vivo performance
• Utilize or develop mathematical models to predict the dissolution of solid particles in aqueous solutions, precipitation of particles from supersaturated aqueous solutions, the release of drug osmotic and multi particulate systems and oral absorption of drug molecules for the design of drug delivery systems
• Provide input and insights to conduct experimental investigations to enable the development of leading-edge in vitro and in silico capabilities for the design of complex drug delivery systems intended to provide desired pharmacological outcomes for patients
• Work in multidisciplinary teams composed of scientists with experience and expertise in biopharmaceutics, oral absorption modeling, pharmaceutical sciences, biology, pharmacology, synthetic organic chemistry, chemical engineering, material science, etc.
• Develop hypotheses, design experiments to test hypotheses, and provide interpretation of data to assist in resolving challenging physicochemical problems associated with drug delivery systems
• Develop or implement computational predictive tools for mass transport such as dissolution of particles, the release of drug from drug delivery platforms, assess self-assembling systems in solution, oral absorption modeling of drug molecules in multi-component systems, and in vitro performance attributes of complex drug products and drug delivery systems and manufacturing processes
• Develop strategic collaborations with academic and industrial researchers for addressing gaps in fundamental or applied science related to biopharmaceutics with a focus on mass transport phenomenon using principles of physics, physical chemistry, and chemical engineering associated with the solution and solid-state thermodynamics of drugs
• Publish research in reputed scientific journals and give presentations at national and international conferences.
• Contribute to writing regulatory submissions to provide a succinct description of well-characterized and modeled drug delivery systems, their manufacture, and their biopharmaceutical performance

Candidate Profile
• Recent PhD and/or with 1-3-year post-doctoral experience in Chemical Engineering, Physical Chemistry, Biophysical Chemistry, Biophysics, Physics, Physical Organic Chemistry, Pharmaceutics, Pharmaceutical Science
• Candidates with experience in allied disciplines may also apply with the following qualifications: Ph.D with minimum 2 years, MS with 5+ years, or BS with 10+ years of experience in the industry
• Experience in understanding and interpretation of experimental thermodynamic and kinetic data and ability to develop relevant computational models for predictive design and performance of novel drug delivery systems with focus biopharmaceutics applications
• Experience in interpretation of experimental thermodynamic and kinetic data associated with biopharmaceutics and drug delivery systems; solve problems by combining data with mathematical modeling of the underlying phenomenon
• Experience in the use of appropriate modeling and computer software and computer programming languages e.g. Matlab, C++, Python for problem-solving
• Strong interpersonal written, and verbal communication skills
• Ability to prioritize and manage multiple projects and activities while meeting tight deadlines
• Proactive in problem-solving and be able to independently manage timelines and priorities
• Ability to work independently to drive the project forward as well as collaboratively in a multidisciplinary team environment
• Work remotely with supervisor and globally located biopharmaceutics and multi-disciplinary team members

Additional Information
Experience : 1-3-year
Qualification : Ph.D
Location : Chennai
Industry Type : Pharma/ Healthcare/ Clinical research
Functional Area : Drug Product Design, Biopharmaceutics
End Date : 20th November, 2021