Research recruitment for Pharmacy professionals at the Department of Gastroenterology and Human Nutrition, AIIMS

The Department of Gastroenterology and Human Nutrition, AIIMS New Delhi is a premier academic and clinical department dedicated to the diagnosis, treatment, and research of gastrointestinal, liver, and pancreatic disorders. It provides comprehensive patient care through advanced diagnostic and therapeutic facilities. The department is actively involved in undergraduate and postgraduate medical education, clinical research, and training. It also focuses on human nutrition, nutritional assessment, and management of nutrition-related disorders. The department was established in 1971 and has played a significant role in developing gastroenterology as a medical specialty in India. It is also actively engaged in advanced research, including studies on gastrointestinal diseases, liver disorders, pancreatic diseases, and gut microbiome.

Position: Senior Project Associate

No. of Positions: 1

Minimum qualification
(i) Four years Bachelor's degree in Natural or Agricultural Sciences /Master's degree in Natural or Agricultural Sciences/ BVSc/B.Pharma or Bachelor's degree in Engineering or Technology or Medicine from a recognized University or equivalent
OR
(i) Master's degree in Engineering or Technology from a recognized University or equivalent
OR
(iii) Doctoral Degree in Science / Engineering/Technology/ Pharma/ MD/Master of Surgery from a recognized University or equivalent

Salary: Rs. 59,790 / month

Experience
(i) Four years 'experience in R&D in Industrial and Academic Institutions or Science and Technology organization and Scientific activities and service.
(ii) Two years' experience in R&D Industrial and academic institutions or S&T organizations and scientific activities and services.
(iii)Nil

Lab & Project Overview:
Our Laboratory has established patient-derived 3D intestinal organoid (colonoid) models for inflammatory bowel disease (IBD), including ulcerative colitis (UC). The current project centers on developing an autologous organoid co-culture systems incorporating Lamina Propria Mononuclear Cells (LPMCs) and Fibroblasts.

Key Responsibilities & Technical Competencies:
Organoid & Cell Culture:
• Adult stem cell-derived human intestinal organoid culture, maintenance, and optimization
• Primary cell culture: fibroblast and lamina propria mononuclear cell (LPMC) isolation and characterization
•Co-culture model development and optimization (organoid + primary cell integration)

Characterization & Assessment:
• Flowcytometry (FACS) - cell sorting. gating, population analysis
• Immunofluorescence and immunocytochemistry (ICC) staining
• Live-cell imaging and confocal microscopy
• Functional cell-based assays

Molecular & Genomic Analysis:
• RT-qPCR and Western blotting/Multiplex protein assay
• scRNA-seq sample preparation and library prep
• Transcriptomics data interpretation