Life Sciences Fellowship at National Institute of Immunology

Applications are invited for the one position of Senior Research Fellow (Project) for the following time-bound sponsored project as per the details given below

Post : Senior Research Fellow (Project) (One position only)

Name of the project & Duration of the Project : “Investigating the Role of Tfh Cells in Shaping Humoral Immunity in Dengue funded by DBT Tenable till-26.04.2029
Name of the Project Investigator and Email ID : Dr. Nimesh Gupta Staff Scientist-V nimesh.gupta@nii.ac.in

Educational Qualifications : M.Sc. or M.Tech in any area of Life Sciences with minimum two years of post M.Sc. experience. Candidates should have cleared nay National Level Examination Test (NET/GATE etc.)
Emoluments : The selected candidates will draw consolidated emoluments as per Institute Rules, depending upon qualifications & experience: Rs. 42,000/- per month plus 27% HRA (As per DST OM dated 26.06.2023)

Job description
This project investigates how Tfh cells regulate antibody responses during dengue infection and contribute to severe disease (See article cell.com/cell- reports/fulltext/S2211-1247(25)00137-8). Using a longitudinal cohort of dengue patients, it integrates immunophenotyping, serological profiling, and single-cell RNA/TCR sequencing to define Tfh-cell signatures and functionally validate mechanisms driving protective versus pathogenic outcomes. The candidate should have experience in handling human clinical samples, including PBMC isolation and plasma processing. Strong expertise in immunological assays is required, particularly T-cell phenotyping (flow cytometry, T-cell assays) and serological analyses (ELISA, neutralization assays). Experience in virus handling and isolation, preferably dengue, is desirable. The candidate should be proficient in RNA-seq workflows, including library preparation and bioinformatics analysis (e.g., Seurat, Cell Ranger, R). Familiarity with single-cell transcriptomics and TCR repertoire analysis is essential. Strong analytical skills and the ability to work in a multidisciplinary team are expected.

General Terms & Conditions
1. The candidates selected for the above posts will be on contract for one year or for the duration of the project, whichever is shorter, at a time.
2. No hostel/ housing facility will be provided.
3. Applicants may clearly mention the category they belong to i.e. SC/ST/OBC/PH and attach documentary proof of the same.
4. No TA/DA will be paid for attending the interview, if called for.
5. Apart from sending application in the prescribed format given below, candidates should send complete Curriculum Vitae along with the names of three referees. Curriculum Vitae should contain details of the experimental expertise and list of publications.
6. Canvassing in any form will be a disqualification.
7. The Interviews will be held in offline/online mode

How to Apply
Interested candidates may apply directly, STRICTLY IN THE PRESCRIBED FORMAT GIVEN BELOW, through E-mail, to the Investigator of the project, clearly indicating the name of the project along with their complete CV, E-mail-ID, fax numbers, telephone numbers. Only Short-listed candidates will be called for interview, and they required to submit attested copies of all their certificates. A demand Draft of Rs 100/- drawn on Canara Bank or Indian Bank payable at Delhi/New Delhi in favour of the Director, NII or can make the payment through UPI/Paytm/Phone Pe etc. in the Bank A/c Beneficiary Name: Director, NII/Account No. 1484101001636/IFSC: CNRB0001484/) and Women & SC/ST/PH Candidates are exempted from payment of fees, (subject to submission of documentary proof), at the time of interview.

Last Date : 16th June, 2026