Job for Scientist in THSTI | Emolument up to Rs. 65,000 / month
Translational Health Science and Technology Institute (THSTI) is an autonomous Institute of the Department of Biotechnology, Ministry of Science and Technology, Govt, of India. The institute is an integral part of the interdisciplinary NCR Biotech Science Cluster located at Faridabad, and is designed as a dynamic, interactive organization with the mission to conduct innovative translational research and to develop research collaborations across disciplines and professions to translate concepts into tangible products to improve human health.
THSTI has set up niche centres for research in areas relevant to planned translational work. They are: Vaccine and Infectious Disease Research Centre (VIDRC), Paediatric Biology Centre (PBC), Centre for Bio-design & Diagnostics (CBD), Drug Discovery Research Centre (DDRC), Centre for Human Microbial Ecology (CHME) and Policy Centre for Biomedical Research (PCBR). Clinical Development Services Agency (CDSA) and National Bio-design Alliance (NBA) are THSTI’s extramural centres.
Post : Scientist - C (Bioassays)
This recruitment is to fill up the vacancy in the project entitled “Chemicalprofiling ofjoha and black rice of NER for nutritional, nutraceutical parameters and aromatic compounds” under Drug Discovery Research Centre of THSTI.
Drug Discovery Research Centre which has been set up as a mission centre of the THSTI to enable the process of drug discovery research in India. It is multi-disciplinary centre where research activities will span the broad areas of Biology, Chemistry and Systems Biology.
Maximum monthly consolidated emoluments : Upto Rs. 66,750/-
Age Limit : 40 years
Qualifications & Experience
M.Sc./ MTech in Life Sciences, Biotechnology or Biochemistry with minimum of four years industrial experience in bio-assays design and development in a CRO or a Drug Discovery setup/ Industry.
Essential: Good knowledge of cell and molecular biology techniques and their use is assay development.
Candidate is expected to lead a team for in vitro screening for functional readout of small molecules to aid pre-clinical drug discovery efforts.
To be a lab-based scientist, delivering expertise in the area of biochemical assay development; independently designing, developing and validating biochemical assays for implementation in drug discovery projects, while incorporating the views of others. Standardization of biochemical assays for small molecules using various platforms like TR-FRET, Fluorescence, Luminescence etc.
Screening of NCEs using standardized protocols. Standardization of cell based assays for various cell lines and screening of small molecules.
CYP inhibition assays, Metabolic Stability, Plasma Stability, Solubility assays, Plasma Protein Binding studies.
Well versed with Western blots & Development of ELISAs.
Literature search, designing and planning of experiments Preparation of SOPs/Protocols. Knowledge of GraphPad Prism
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