January 2010

Intensive insulin therapy does not show a survival benefit for patients treated with hydrocortisone for septic shock, according to the results of a multicenter, 2 x 2-factorial, randomized controlled trial reported in the January 27 issue of the Journal of the American Medical Association.

ImmunoCellular Therapeutics, Ltd. (IMUC) announced the results of a study in which it was shown that certain specific antigens are highly expressed on cancer stem cells (CSCs). This suggests that IMUC’s lead cancer vaccine product candidate ICT-107, which targets those antigens, may effectively target not only the cells that make up the bulk of certain cancerous tumours, but also the CSCs that are widely believed to give rise to them and cause their recurrence.

Living Cell Technologies Limited (LCT) announced that it has been granted a European patent for the use of its product NTCELL in the treatment of degenerative neurological conditions such as Parkinson’s disease, Alzheimer’s disease, multiple sclerosis (MS), Huntington’s disease and stroke.

Researchers at the National Institutes of Health (NIH) and other institutions have discovered the third in a sequence of genes that accounts for previously unexplained forms of osteogenesis imperfecta (OI), a genetic condition that weakens bones, results in frequent fractures and is sometimes fatal.

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