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Opportunity for pharmacy graduates as Junior Analyst in the Drugs Testing Laboratory - 14 posts | Permanent Government job

 

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Applications are invited only through online mode upto 20.12.2017 for Direct Recruitment to the following posts:- It is mandatory for the applicants to register their basic particulars through One Time online Registration system on payment of Rs.150/- (Rupees One Hundred and Fifty only) towards registration fee and then should apply online for this recruitment. (The One Time Registration will be valid for 5 years from the date of registration. Thereafter, the registration should be renewed by paying the prescribed fee.)

Post: Junior Analyst in the Drugs Testing Laboratory

Number of vacancies: 14

Scale of Pay: Rs.9,300-34,800/- (PB2) + 4,600/- G.P Pre-revised

Qualification:
A Degree in Pharmacy and Experience in the analysis of drugs for a period of not less than one year.
or
A Degree in Chemistry or A Degree in Pharmaceutical Chemistry and Experience in the analysis of drugs for a period of not less than two years.
or
Candidates who possess Post Graduate Degree in Chemistry with Analytical Chemistry as a special subject. Experience in the analysis of drugs for a period of not less than one year.

 

AGE (as on 01.07.2017)
SCs, SC(A)s, STs, MBCs/DCs, BCs, BCMs and DWs of all Castes- No Maximum Age limit
“Others” [i.e. Applicants not belonging to SCs, SC(A)s, STs, MBCs/DCs, BCs and BCMs] - 30 Years (Should not have completed)

MODE OF PAYMENT OF EXAMINATION FEE
- Examination fee Rs.150/- (Rupees One Hundred and Fifty only) is payable online through Net banking / Credit card / Debit card or it can be paid offline at SBI / Indian Bank within 2 days from the date of submission of online application, by choosing the option in the online application.
- Applicants have to register their basic particulars through One Time Registration which is mandatory on payment of Rs.150/- (Rupees One Hundred and Fifty only) towards registration fee and then should apply online for this recruitment. The One Time Registration will be valid for 5 years from the Date of Registration. Thereafter, the registration should be renewed by paying the prescribed fee. Applicants who have already registered in One Time Registration system on payment of Rs.50/- before 01.03.2017 and those who have registered for One Time Registration on or after 01.03.2017 by paying Rs.150/- towards One Time Registration are exempted from paying the registration fee for this recruitment.
- Applicants have also to pay the service charges applicable to the State Bank of India / Indian Bank.
- Applicants can avail exemption from paying examination fees as per eligibility criteria.
- Offline mode of payment in the form of Demand Draft / Postal Order etc., will not be accepted and the applications forwarded with such modes of payment will be summarily rejected.
- Those who have registered in the One Time Registration system, and paid the registration fee of Rs.150/- and received the registration ID need not pay the Registration fee i.e., Rs.150/- and it is enough to pay the examination fee alone.
- Applicants who have made One Time Registration must pay the prescribed examination fee for this recruitment unless fee exemption is claimed. (One Time Registration is only to avail exemption for Registration fee for a period of 5 years from the date of registration and it will not be considered as prescribed examination fee for this recruitment).

SCHEME OF EXAMINATION OBJECTIVE TYPE (OMR METHOD) AND ORAL TEST:-

i. Paper - I Degree Standard (200 Questions) Pharmacy(Code No.246) Pharmaceutical Chemistry (Code No.245) *Chemistry(Code No.243) {3 hours, 300 marks}

ii. Paper - II GENERAL STUDIES (100 Questions) (Code No-003) General Studies (Degree Standard) – 75 Questions and Aptitude and Mental Ability (SSLC Standard) – 25 Questions. {2 hours, 200 marks}

iii. Interview and Record {70 marks}

Minimum Qualifying Marks for Selection:
SCs, SC(A)s, STs, MBCs/DCs, BCs and BCMs - 171
Others - 228

* For those who have studied PG Degree in Chemistry with Analytical Chemistry as a Special Subject.

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KNOWLEDGE IN TAMIL
Applicants should possess adequate knowledge in Tamil on the date of this Notification.

SELECTION PROCEDURE
Selection will be made in two successive stages i.e., (i) Written Examination and (ii) Oral Test in the form of an interview. Final selection will be made on the basis of total marks obtained by the candidates at the Written Examination and Oral Test taken together subject to the rule of reservation of appointments. Appearance in both the papers of the Written Examination and Oral Test is compulsory. A candidate who has not appeared in any one of the papers in Written Examination or Oral Test will not be considered for selection, even if he/she secures qualifying marks in the Written Examination or Oral Test.

HOW TO APPLY
1. Applicants should apply only through online mode in the Commission’s Websites tnpsc.gov.in / tnpscexams.net / tnpscexams.in.

2. One Time Registration (OTR) and applicant Dashboard are mandatory before applying for any post. Applicant should register only once in the One Time Registration by paying Rs.150/- as Registration fee. Successfully registered One Time Registration is valid for 5 years from the date of Registration. All the applications should be submitted using the One Time Registration ID and password registered by the applicant.

3. For applying in One Time Registration, the applicants should have scanned image of their photograph, certificate wherever insisted and signature in CD/DVD/Pen Drive to upload the photo, certificate and signature.

4. Applicants who have already registered in One Time Registration on or before 29.09.2015 shall use their existing user ID and Password to create applicant Dashboard in the new One Time Registration system. No applicant is permitted to create more than one registration ID in One Time Registration.

5. Applicants should enter the Unique ID and password to view the already available information and update them

6. One Time Registration is not an application for any post. It is just a collection of information from the applicants and giving a separate dashboard to each applicant to facilitate them to maintain their own profile. Applicant who wishes to apply for any post shall click “Apply” against the post Notified in the Commission’s Website and use the same USER ID and PASSWORD given for ONE TIME REGISTRATION.

7. Applicants should select the name of the post or service for which they wish to apply.

8. Applicants are required to upload their photograph and signature as per the specifications given in the Guidelines for Scanning and Upload of Photograph and Signature.

9. An Online application uploaded without the photograph, specified documents and signature will be rejected.

10. All the particulars mentioned in the online application including name of the Candidate, Post applied, educational qualifications, Communal Category, Date of Birth, Address, Email ID, Centre of Examination etc. will be considered as final and no modifications will be allowed after the last date specified for applying online. Since certain fields are firm and fixed and cannot be edited, applicants are requested to fill in the online application form with the utmost care and caution as no correspondence regarding change of details will be entertained.

11. Print Option
a) After submitting the application, applicants can print / save their application in PDF format.
b) On entering user ID and password, applicants can download their application and print, if required.
c) Need not send the printout of the online application or any other supporting documents to the Commission. The certificates will be verified only when the applicants come up for next stage of selection.

12. One Time Registration will not be considered as an application for any post.

GENERAL INFORMATION
A. The rule of reservation of appointments is applicable to this recruitment except for the post of
Archaeological Chemist. The distribution of vacancies will be as per rule in force.
B. In G.O.Ms.No.145, Personnel and Administrative Reforms(S) Department, dated 30.09.2010 and G.O.Ms.No.40, Personnel and Administrative Reforms(S) Department, dated 30.04.2014, the Government have issued orders to fill up 20% of vacancies in direct recruitment on preferential basis to Persons who studied the prescribed qualification in Tamil Medium. The 20% reservation of vacancies on preferential allotment to Persons Studied in Tamil Medium (PSTM) will apply for this recruitment. Applicants claiming PSTM preference must produce certificate issued by Head of Institution as proof as per the specimen contained in the “Instructions to Applicants” for having studied the prescribed qualification in Tamil Medium. (Having written the examination in Tamil language alone will not qualify for claiming this preference). If the Applicants with PSTM certificate are not available for selection for appointment against reserved turn such turn shall be filled up by other eligible Applicants but belonging to the respective communal category. The PSTM certificate, in prescribed format / proforma available in the Commission’s website at ‘www.tnpsc.gov.in’ shall be obtained from the Head of the Institution and shall be produced / uploaded when called for. (For further details refer Instructions to Applicants) However, no reserved turn to PSTM candidate arises for the posts of Junior Chemist, Chemist and Archaeological Chemist.
C. The number of vacancies advertised is only approximate and is liable to modification with reference to vacancy position at any time including reduction before finalization of selection.
D. The selection for appointment to the above said posts are purely provisional subject to final Orders on pending Writ Petitions, if any, filed at Madras High Court and Madurai Bench of Madras High Court.
E. As per the Section 26 and 27(c) of Tamil Nadu Government Servants (Conditions of Service) Act, 2016, reservation of appointment to Destitute Widows and Ex-Serviceman respectively will not apply to this recruitment.
F. If the posts are identified as suitable for Differently Abled persons of any category, the reservation of 4% for Differently Abled persons as per G.O.Ms. No. 21, Welfare of Differently Abled Persons (DAP3.2) Department, dated 30.05.2017 will be made applicable. Hence, the Differently Abled persons may apply to this recruitment. Their application will be accepted subject to the orders to be issued by the Government.
G. The Differently Abled persons should submit copy of Differently Abled Certificate specifying the nature of physical handicap and the degree of disability when called for by the Tamil Nadu Public Service Commission.
H. If no qualified and suitable women applicants are available for selection against the vacancies reserved for them, those vacancies will be filled by male applicants belonging to the respective communal categories.
I. Even after filling up of the vacancies reserved for SC Arunthathiyars on preferential basis, if more number of qualified Arunthathiyars are available, they shall be entitled to compete with the Scheduled Castes other than Arunthathiyars in the inter-se merit among them and if any post reserved for Arunthathiyars remain unfilled for want of adequate number of qualified Applicants, it shall be filled up by Scheduled Castes other than Arunthathiyars. However, no required turn to SC(A) candidates arises except for the post of Junior Analyst.
J. Evidence for claims made in the online application should be uploaded / submitted in time when called for the documents. Any subsequent claim made thereafter on submission of online application will not be entertained. Failure to submit the documents within the stipulated time limit will entail rejection of the Application.
K. Correct and True information regarding arrest, convictions / debarment / disqualification by any recruiting agency, criminal or any disciplinary proceedings initiated / pending or finalized, participation in agitation or any Political Organization, candidature in election for Parliament/State Legislature/Local Bodies etc., if any, should also be furnished to the Commission at the time of application i.e., the details thereof, originals of the Judgement, order or G.O dropping further action in Departmental proceedings or any document that may prove the suitability of such Applicants for a Government appointment in such cases must be produced at the stage / time of Certificate Verification without fail.
L. Incomplete applications and applications containing wrong claims or incorrect particulars relating to category of reservation / other basic qualification / eligibility wise / age / communal categories / educational qualification / physical qualification and other basic eligibility criteria will be liable for rejection.
M. One Time Registration is not an application for any Post / Recruitment. Though the details / particulars were furnished in the One Time Registration by the applicants, the details/particulars furnished in the online application submitted for this recruitment alone will be taken into consideration. Tamil Nadu Public Service Commission will not be responsible for any consequences arising out of furnishing of incorrect and incomplete details in the application or omission to provide the required details in the application for this recruitment.

UPLOAD OF DOCUMENTS
Applicants should upload or submit the Certificate of Experience referred to the said posts in paragraph 6(B) of the Notification as provided in Annexure – II when called for. If, the required certificate is not uploaded or submitted by the applicant when called for at any point of time by the Commission his/her application will not be considered for the above posts.

LAST DATE FOR SUBMITTING APPLICATION
The Online Application can be submitted upto 20.12.2017 till 11.59 p.m., after which the link will be disabled.

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TAMIL NADU PUBLIC SERVICE COMMISSION
(JUNIOR ANALYST) – MAIN WRITTEN EXAMINATION

PAPER – I PHARMACY (DEGREE STANDARD) OBJECTIVE TYPE
CODE NO.246

UNIT- I
a) The physical, physico-chemical and engineering principles governing design, layout and operation of plants for the process employed in pharmaceutical industry.
b) Unit operations: size reduction, size separation, mixing, compression, filtration, centrifugation, extraction, evaporation, drying, distillation, crystallization.
c) Industrial Hazards and Safety Precautions: Mechanical, Chemical, Electrical,
Fire and Dust hazards, Industrial dermatitis, Accident records
d) Containers, closures and packaging materials
e) Preformulation Studies
f) Pharmaceutical excipients: Antioxidants, preservatives, Colouring, Flavouring and Sweetening agents, Solvents.
g) Facts related with formulation:- Physical properties, particle size. Crystal from, flow cohesiveness. Solubility. Chemical properties, Hydrolysis.Oxidation racemization, enzymatic decompositions.
h) pH determination, application, buffer equation, buffer capacity,buffered isotonic solutions; Micrometrics: Particle size determinations, derived properties of powders; Interfacial phenomenon : HLB values surfactants, factors influencing interfacial phenomenon, Critical micellar concentration, Electrical properties at interface; Coarse dispersions: Suspensions and emulsions, Theories of emulsification, multiple emulsions.
i) Pharmaceutical calculations: Calculations of doses, alcohol dilutions, proof spirit, isotonic solutions.
j) Nuclear Pharmacy- Introduction to Radiopharmaceuticals, radioactive half-life, units of radioactivity. Production of radiopharmaceuticals, methods of isotopic tagging, preparation of radioisotopes in laboratory using radiation dosimetry and radioisotope generators. Permissible radiation dose level, radiation hazards, their prevention and specifications for radioactive laboratory.
k) Good Manufacturing Practice
l) Quality control, of the following formulations: Semisolids, Solid dosage forms,
Liquid dosage forms, Parenteral and ophthalmic preparations
m) New Drug Delivery Systems- Aerosols, Ocusert, Transdermal Drug Delivery Systems, Osmotic Drug Delivery Systems, Targeted Drug Delivery Systems, Prolonged Drug Delivery Systems
n) Cosmetics- Dentifrices, Lipsticks, Face powders, shampoos, depilatories and Manicure preparations

UNIT- II
a) Blood Products and Plasma Substitutes: Collection, processing and storage of whole human blood, concentrated human RBCs, dried human plasma, human fibrinogen, human thrombin, human normal immunoglobulin, human fibrin foam, plasma substitutes, ideal requirements of PVP, dextran, etc. Control of blood products as per IP.
b) Basics of pharmacokinetic studies and their importance
c) Pharmaceutical Biotechnology- General principles of immunology, immunological techniques used in pharmacy; Sterilization of different pharmaceutical dosage forms; Sterility Testing; Methods of preparation of official sera and vaccines; Microbiological assays of antibiotics and vitamins of the pharmacopeia; Disinfectants- Classification, Mechanism and uses of disinfectants in brief. Factors affecting disinfection and methods of disinfectant evaluation.
d) Immunologicals: Preparation and quality control of products representing various categories like
Toxoids – Diphtheria and Tetanus,
Live Bacterial Vaccines – BCG
Killed Bacterial Vaccines – Cholera, DPT.
Viral Vaccines – Polio, Rabies and small pox
Antitoxins – Diphtheria

UNIT - III
a) Chemistry of Alkaloids, Vitamins, Flavanoids, Glycosides, steroids, terpenes, vitamins and hormones.
b) Catalytic hydrogenation, dehydrogenation, metal hydride reduction. Reduction with hydrazine and its derivatives, Birch reduction, Clemenson’s reduction, Meerwin – Ponndrof reduction, oxidation with periodic acid, lead tetra acetate, mercuric acetate and selenium oxide. Beckmann rearrangement, Schmidt rearrangement and Darzen’s reaction.

UNIT - IV
Synthesis, properties, test for purity, storage of the following categories of drugs - Analgesics and Antipyretics, Anti-inflammatory, Hypnotics and sedatives, Anti convulsants, Anti-psychotics, Anti-histamines, Sympathomimetics, Adrenergic antagonists, Cholinomimetics and anti-cholinergic, Local Anaethetics, Anti- hypertensives, Anti-anginal, Sulphonamides,antibiotics, Anti-TB, Anti-Viral, Anti- Fungal, Antimalarials, Anti-Neoplastics,

UNIT- V
a) Principles and Pharmacopeial Assay Procedures involving Non-aqueous Titration, Oxidation-Reduction, Diazotization, complexometric methods, electrometric titration, gravimetric analysis
b) Polarimetry and refractometry, and gasometric analysis of oils, fats and waxes
c) Chromatography- TLC, Column, Paper, GC, Ion exchange, HPLC, HPTLC, Gel electrophoresis,
d) Theory, principle, instruments and applications of colorimetry, UV- Visible Spectrometry, Fluorimetry, Nephalometry, Turbidometry, IR, Mass, NMR, RIA.

UNIT- VI
a. General Pharmacology:- Routes of adminstration, Absorption, distribution, Biotransformation and Extretion of drugs, Bioavailability and bio equivalence, Factors affecting bioavaliability, Mechanism of action of drugs at receptor level, adverse drug reaction;
b. Drugs acting on Central Nervous system: Analgesics, Nonsteroidal anti inflammatory drugs, Sedatives and Hypnotic, Anti convulsants and Antipsychotic drugs. Drugs used in parkinsonism.
c. Drugs acting on Autonomic Nervous system: Drugs which influence the working of autonomic nervous system, Adrencrgic drugs (or) sympathominitic drugs, Adrenergic blocking drugs, Cholinergic drugs and cholinergic blocking drugs, Drugs acting on autonomic ganglia.
d. Drug acting on cardiovasular system: cardiac glycosides, Anti hypertensive, anti- arrhythmic and anti anginal drugs.
e. Diuretics & anti diuretics

UNIT- VII
a. Drugs acting on GIT
b. Insulin and oral anti diabetic drugs, Thyroid and anti-thyroidal drugs, oral contraceptives. Hormone replacement therapy, drugs acting on uterus.
c. Antihistaminic drugs and Drugs used in Migraine
d. Chemotherapy- sulphonamides penicillins, cephalosporins, quinolones, Tetracyclines, Aminoglycosides, Chemotherapy of Tuberculosis, leprosy, malaria, cancer , Ameobiasis, Helminthiasis.
e. Toxicology- Systematic & local treatment of poisoning and their treatment.

UNIT- VIII
a. General principles of cultivation and collection of drugs from wild & cultivated sources, their merits and demerits, factors affecting cultivation, adulterants and their detection
b. Plant growth regulators
c. Source, synonym, cultivation, collection, preparation for market, diagnostic characters (both macroscopical and microscopical). Constituents, substitutents, adulterants and uses of Cinnamon, Cinchona, Senna, digitalis, Clove, Saffron, Pyrethrum. Cochineal, Ergot, opium, Aloe, Acacia, Tragacanth, Benzoin, Ginseng, Brahmi, Dioscorea, Cascara, Gelatin, umbelliforous fruits, spirulina, nuxvomica, ginseng, belladonna, taxol , vinca.
d. Principle and application plant tissue culture.
e. Basics of fermentation technology & production of Antibiotics, Vitamins.

UNIT- IX
a. Biosynthetic pathways of Tropane alkaloids, Cholesterol, amino acids.
b. WHO Guidelines for herbal medicines

UNIT- X
a. Drugs and Cosmetics Act 1940 and Rules 1945
b. Pharmacy Act 1948

ANNEXURE – III
TAMIL NADU PUBLIC SERVICE COMMISSION
(JUNIOR ANALYST) – MAIN WRITTEN EXAMINATION
PAPER – I PHARMACEUTICAL CHEMISTRY (DEGREE STANDARD)
Code No.245

UNIT I
1) Atomic structure and valency, Radioactivity, Radio isotopes and Pharmaceutical applications of Radio Pharmaceuticals, hazards and precautions.
2) Sources of impurities in Pharmaceutical substances; Limit test as per I.P; Fundamentals of volumetric Analysis.
3) A systematic study of inorganic compounds for their preparation, assay and use which includes Gastrointestinal agents, Topical agents and Dental products.

UNIT II
1) Assay, test for purity of sodium, calcium, iron, aluminium and ammonium compounds. Major intracellular and extra cellular electrolytes.
2) Preparation and use of Chemical reagents and Volumetric Solutions as per Pharmacopia in Pharmaceutical Analysis.
3) Theory of Co-ordination Compounds with special reference to application in Pharmaceutical Analysis via EDTA, Dimercaprol, Pencillamine.

UNIT III
1) Physiochemical properties of gases, liquids and solids. Density, Surface tension, Viscosity and physical properties.
2) Osmosis, osmotic pressure, vapour pressure, Raoult's law, Ostwalds dilution law, Molecular weight determination by osmotic pressure.
3) Non- aqueous and complexometric titrations, analysis of fats, oils and waxes. Importance of quality control, Different types of titrations, Gasometric analysis and determination of Nitrogen.

UNIT IV
1) Gases in liquids, liquids in liquids, partially miscible, completely miscible and completely immiscible liquids.
2) Thermochemistry: Heat of reaction, heat of solution, heat of formation and heat of neutralization and Hess law.
3) Stereo chemistry, optical isomerism, Geometrical isomerism.
4) Theory of Polarimetry, Refractometry and catalyst.

UNIT V
1) Electronic configuration and electron displacement effects, chemical bonds and polarity.
2) Chemistry and medicinal uses of cardiac glycosides and vitamins.
3) Synthetic utility of acetoacetic ester, Grignard reagent and Diazonium compounds.

UNIT VI
1) Aromaticity,concept of resonance, Nucleophilic, Electrophilic substitution reaction, Elimination reactions in aliphatic and aromatic compounds.
2) Anti-infective agents comprising of Anti-fungal agents, synthetic antibacterial agents, anti-tubercular Agents, and Anthelmintics agents.

UNIT VII
Chemical structure, Synthesis, assay and therapeutic uses of organic synthetic drugs like, Antidepressants, General anesthetics, Sedatives and hypnotics, Narcotic analgesics, Anti -histaminics, Antimalarials., Sulphonamides, Drugs acting on CVS.

UNIT VIII
1) Structural elucidation of natural products - General methods.
2) Structure, chemistry, methods of estimation, and uses of Alkaloids, Carbohydrates, and Proteins.
3) Chemistry of steroids and natural hormones, currently used steroidal drugs.

UNIT IX
1) Study of separations and determination involving TLC, HPTLC, and column chromatography.
2) Colorimetry, UV and Visible Spectrophotometry, Spectrofluorimetry-Theory, Principle, Instrumentation and working.
3) Theory and principles of separation techniques involving Ultra centrifugation, HPLC and Gel filtration.

UNIT X
1) Conductometry, Potentiometry and Amperometric titrations, Basic concepts and application in pharmaceutical analysis.
2) Radio Immuno Assay and Electrophoresis.
3) Theory, Principle and application of NMR, MS, IR spectroscopy.

ANNEXURE – III
TAMIL NADU PUBLIC SERVICE COMMISSION
(JUNIOR ANALYST) – MAIN WRITTEN EXAMINATION
PAPER – I CHEMISTRY (DEGREE STANDARD) OBJECTIVE TYPE
CODE NO.243

UNIT - I
PHYSICAL CHEMISTRY:-
a) Gas law and Kinetic Theory:- Ideal gas equation - Deviation from ideal behaviour - vander waals equation for real gases - Molecular velocities - the Maxwell's distribution of molecular velocities –heat capacity and viscosity of gases.
b) Solid State:- Crystal systems - Bravaislattice - Unit Cell - Miller Indices - Symmetry elements in crystals - Bragg's equation - Radius ratio's and packing in crystals – Determination of crystal structures by Braggs method – structure of Nacl, Kcl, Zns and spinals.
c) Thermodynamics:- Intensive and extensive variables - First law of thermodynamics – CP and CV relation - Hess's law of constant heat summation - Kirchoff's equation - Second law of thermodynamics - Carnot theorem - entropy and probability, Joule Thomson effect -Free energy and Chemical equilibrium - Temperature and pressure dependence and - Gibb's and Helmholtz functions – Heterogeneous equilibrium and Le – Chatlier principle.

UNIT - II
d) Chemical Kinetics:- Rate laws - rate constant - order and molecularity of reactions I, II, III, and Zero order reaction Arrhenius theory - collision theory and Transition state theory - catalysis.
e) Electro-Chemistry:- Types of reversible electrodes - Nernst equation - reference electrode and standard hydrogen electrode - computation of cell e.m.f. calculations of thermodynamic quantities of cell reactions (DG, DH, DS and K) - Over potential and hydrogen over voltage - Arrhenius theory - Debye 'Huckel equation - Kohliraush's law - Ostwald's dilution law - Determination of PH and Pka of acids by potentiometric methods.

UNIT - III
f) Chemical spectroscopy:- Elementary ideas of microwave, infrared, Raman, uv, NMR, ESR and Mass spectroscopy.
g) Pharmaceutical chemistry: Terminology pharmacology, pharmacotheraies, toxicology, chemotherapy, classification, and nomenclature of drugs, sources of drugs, assay of drugs by biological, chemical and immunological methods, physiological effects of functional groups of drugs different types of drugs like analgesics, antibiotics, antiseptics, disinfectants, anesthetics, antidepressants, antipsychotic etc.

UNIT - IV
h) Colloids and surface Chemistry:- Classification – preparation, purification - properties - Tyndall effect- Gels - Emulsions Absorption - Langmuir isotherms - Heterogeneous catalysis.
i) Physical properties and Chemical constitution:- Surface tension - parachor and its application to structural problems – Dipole moment - applications of dipolemoment measurements to structural studies of simple inorganic and organic molecules - magnetic properties of matter, diamagnetism, paramagnetism, ferromagnetism and anti- ferromagnetism - Applications to structural problems.

UNIT - V
INORGANIC CHEMISTRY:-
j) Periodic classification:- Classification based on electronic configuration - periodic properties - atomic and ionic radii, ionisation potential, electron affinity and electronegativity- various scales - trend along periods and groups.
k) Chemical bond:- Lattice energy - VSEPR Theory and its applications - partial ionic character from electronegativity - Fajan's Rules.
l) Compounds of Boron:- Electron deficient nature of boron compounds - preparation and properties of halides and nitrates of boron - diborane – Borazine, silicones and structures of silicates

UNIT - VI
LANTHANIDES AND ACTINIDES:-
m) Ocurrence Electronic configuration oxidation state, magnetic properties and complexation behaviour - comparison of lanthanides and actinides, lanthanide contraction and their position in the periodic table.
n) Fertilisers:- Ammonium nitrate, ammonium phosphate, Superphosphate and Diammonium Phosphate, NPK fertilisers.
o) Nuclear Chemistry:- Radio activity – detection and measurement – half life period - Nuclear stability, - n/p ratio - isotopes, isobars and isotones Nuclear reactions Spallation - Nuclear fission and fusion – stellar energy uses of nuclear energy - nuclear power projects in India - applications of tracers in industry, medicine, agriculture.

UNIT - VII
p) Co-ordination Chemistry:- Redo Nomenclature - theories of co-ordination compounds - Werner, valence bond, crystal field and ligand field theories - Effective atomic number - isomerism - Metal Carbonyls of iron and Nickel.
q) Analytical Chemistry:- i) Principles of volumetric analysis - different types of titrations gravimetric analysis - separation and purification techniques.

UNIT - VIII
ORGANIC CHEMISTRY:-
r) Types of reactions:- Nucleophilic, electrophilic, free radicals, addition and elimination reactions.
s) Electron displacement effects:- Inductive, inductometric, electromeric, mesomeric, resonance, hyperconjugation and steric effects.

UNIT - IX
t) Nature of Bonding:- Hybridisation (Sp, Sp2 & Sp3) and Geometry of molecule - cleavage of bonds - homolytic and heterolytic fission of carbon – carbon bonds - Reaction intermediates - free radicals, carbocations and carbonions - their stability.
u) Stereo Chemistry:- Optical isomerism and Geometrical isomerism - chirality - optical isomerism of lactic and tartaric acid - Racemisation - Resolution - Asymmetric synthesis - walden inversion - cis and trans isomerism of maleic and fumeric acids - R-S-Notations - conformational analysis of cyclohexane - applications of ORD and CD Techniques.

UNIT - X
v) Dyes:- Classification and Properties of dyes – methyl orange, cangored, malachite green, fluorenscein and indigo.
w) Carbon hydrates:- Classification and reactions - Glucose, Fructose, Sucrose and lactose- structure of glucose and fructose.
x) Aromatic Substitution:- Mechanism of nitration, Halogenation, sulphoration and Friedel Crafts reaction - Orientation effects - nucleophilic substitution - Benzyne mechanism.

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