Articles

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ABOUT AUTHORS
*R.Karthikeyan, E.Meghana, N.Gowthami, MD.Shajiya sultana, B.Mahesh reddy, SK.Magbul Johny, P.Srinivasa Babu
Department of Pharmacognosy, Vignan Pharmacy College, Vadlamudi – 522213.A.P
*rkcognosy@gmail.com

ABSTRACT
The synthesis of nanostructure substances, specifically metal nanoparticles, has accrued utmost concern over the last decade owing to their particular properties that cause them to applicable in distinctive fields of technology era. The biological technique of nanoparticle synthesis is a relatively easy, reasonably-priced, and environmental friendly approaches than the conventional chemical technique of synthesis and accordingly profits a top hand. The bio mineralization of nanoparticles in protein cages is one among such biological approaches used inside the era of nanoparticles. In this review we attempted to explore different techniques of synthesis of nanoparticles and its characterization. Further this review extended the usage of such nanoparticle in different fields.

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ABOUT AUTHOR
Ms. Sapna
Department of Pharmaceutical Sciences
Himalayan Institute of Pharmacy and Research Rajawala, Dehradun, Uttarakhand, India
*bhandarisapna747@gmail.com

ABSTRACT: The present investigation deals with development of orally disintegrating tablets of Rizatriptan Benzoate to produce the intended benefits. Orally disintegrating tablets of Rizatriptan Benzoate were prepared by wet granulation method to provide faster relief from pain to migraine sufferers. Formulation research is oriented towards safety, efficacy and quick onset of action of existing drug molecule through novel concept of drug delivery. About four formulations for the present study were carried out full factorial design. Kyron 314 was used as super disintegrants, while microcrystalline cellulose and mannitol was used as diluents. Starch was used as binder. The prepared batches of tablets were evaluated for weight variation, hardness, friability, wetting time, drug content and in-vitro dissolution studies. The optimized formulation dispersed in within 15 seconds. It also showed a higher water absorption ratio and 99.67% of drug is released within a minute.

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D. Giri Raja Sekhar*, D. Sai Sravani, H. Thulasi , Chakka  Gopinath
Department of Pharmacy Practice, Annamacharya college of Pharmacy, Rajampet
*giriraj.pharma@gmail.com

ABSTRACT: 
The thyroid gland produces thyroid hormones. The two most important hormones are tetraiodothyronine (thyroxine or T4) and triiodothyronine (T3).Iodine deficiency is a major health problem in India. Iodine deficiency that can lead to disorders like goiter, hypothyroidism and even brain damage. Even mild iodine deficiency in pregnant women can result in children being born with cretinism and mental retardation. The most popular method of tackling the problem has been to encourage the consumption of iodised salt. An iodine patch, designed like a regular bindi, is expected to help iodine deficiency. It seems like a brilliantly simply idea The wearing of bindis form part of a cultural practice of Indian Women, which are “self-adhesive” in between their eyebrows, have been impregnated with a solution of iodine.  Production costs are minimal, wearing the iodine-infused bindi requires no behavioral change.

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ABOUT AUTHORS
Devender Sharma*,  Dr. Satish Kosalge1, Snehal R. Dixit1
Hi – Tech college of pharmacy, Chandrapur (M.S.)
*sdevender350@gmail.com

ABSTRACT
Aging is one of the phases of individual’s life span, which everyone wants to escape. The process of aging is much more a social phenomena than biological phenomena. Aging brings many changes such as, loss of eyesight, hearing loss, dementia, etc. Aging may give rise to diseased states such as, heart disease, cancer, cerebrovascular disease (relating to blood vessels that supply the brain), pneumonia and flu, and chronic obstructive pulmonary diseases. The key-factor behind aging is the GDF11, i.e., Growth and Differentiation factor-11. GDF11 is also known as Bone Morphogenetic Factor-11 (BMP11). It is termed as key circulating ‘anti-aging’ factor. GDF11 is expressed in wide range of tissues and has been shown to play important roles in development of olfactory system, retina and pancreas. It functions in regulating anterior-posterior patterning of the axial skeleton muscle system. Scientists theorize that aging likely results from a combination of many factors viz., Lifestyle, Diseases and Genes. GDF11 is essential for mammalian development and has been suggested to regulate aging of multiple tissues, whereas myostatin is a well-described negative regulator of postnatal skeletal and cardiac muscle mass and modulates metabolic processes .

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Manimala M*, Vijay Kumar D
Santhi ram College of Pharmacy
Kurnool, Andhra Pradesh, India
*manimala.mosey@gmail.com

ABSTRACT:
The word “forensic” means “pertaining to the law”; forensic science resolves legal issues by applying scientific principles to them. Forensic Analysis is the application of Analysis to law enforcement or the failure of products or processes. It is unique among chemical sciences in that its research, practice, and presentation must meet the needs of both the scientific and the legal communities.Forensic Analysis applied the basic theory and mythology of advanced analytical chemistry to rationalize various materials of crimes and provide evidence to detection.Forensic Analysis is carried out by the two types of techniques namely Organic Analytical Technique &In- Organic Analytical Technique. And this review article covers regarding how Analytical techniques are useful in forensic analysis to resolve major problems of common man.

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S. Dhivya*, DR. A. N. Rajalakshmi
Department of Pharmaceutics,
Mother Theresa Post Graduate and Research Institute of Health Sciences,
Gorimedu, Puducherry, India
*dhivyaraji310@gmail.com

ABSTRACT: Design and development of herbal nanoparticles has become a frontier research in the nanoformulation arena. Curcumin, a hydrophobic polyphenol (diferuloyl methane) is a potent phytomolecule obtained from turmeric (Curcuma longa, Family-Zingiberaceae) has a wide range of biological activities in chronic diseases and has wide therapeutic efficacy. But the clinical application of curcumin was limited due to its poor water solubility, rapid metabolism and rapid elimination which ultimately results in poor bioavailability upon oral administration. Therefore introduction of nanotechnology provides a solution towards increased bioavailability of curcumin. In this review, an overview of curcumin nanoparticles is discussed.

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ABOUT AUHTHORS
M. Manasa Rekha*,
Department of Pharmacy Practice,
Annamacharya college of Pharmacy,
Rajampet, Andhra Pradesh,  India.
*manasarekharoyal@gmail.com

ABSTRACT: AIM: The study aims to assess the role of DOCTOR OF PHARMACY in identifying drug related problems in inpatient units in a tertiary care teaching hospital. OBJECTIVES: The main objective of the present study includes identification and reporting of drug related problems like Drug-drug interaction, Adverse drug reactions, Drug use without indication, Therapeutic duplication, Allergy/intolerance/poisoning, Improper drug, dose, route, regimen, Awareness/adherence problems.

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RATIKANTA SAHOO, PRATYUSH KUMAR DAS*
Centre for Biotechnology,
Siksha ‘O’ Anusandhan University,
Bhubaneswar, Odisha, India
pratyushdas@soauniversity.ac.in

ABSTRACT
Bromelain is a plant protease present in different parts of the pineapple [AnanasComosus (Linn.) Merr.]plant. It is an enzyme of high commercial interest which can be attributed to the wide therapeutic and industrial applications it possesses. As such efficient purification and recovery of the enzyme is utmost necessary on a large scale basis. The review highlights the numerous applications of the protease enzyme and further discusses the various purification techniques beginning from simpler ultrafiltration to the more complex and specific column chromatography that are being commonly employed nowadays. Effort has been made to compare the purification strategies extensively and suggest the best among the techniques which is cost-effective, has high output and can be used on a large scale production basis.