




June 2017 ARTICLE LIST >>
PharmaTutor (June - 2017)
ISSN: 2347 - 7881
(Volume 5, Issue 6)
Received On: 17/02/2017; Accepted On: 06/03/2017; Published On: 01/06/2017
AUTHORS:
Naveen Kumar G.S* 1, U. Srinivas2, Hanumanthchar Joshi 3
1 Department of Pharmaceutical Analysis,
Sarada Vilas College of pharmacy,
Mysuru, Karnataka, India
2 Department of Pharmacognosy,
Srinivas College of pharmacy, Mangalore, Karnataka India,
3 Department Pharmacognosy,
Sarada Vilas College of pharmacy, Mysuru, Karnataka India
*naveengs.2010@gmail.com
ABSTRACT:
An UV spectrophotometric method using simultaneous equation was developed for the simultaneous determination of meclizine and folic acid in a binary mixture. In the proposed method, the signals were measured at 390.0 nm and 237.0 nm corresponding to absorbance maxima of and folic acid in methanol respectively.
How to cite this article: Naveen KGS, Srinivas U, Joshi H;Development and Validation of Spectrophotometric Method for simultaneous estimation of Meclizine and Folic Acid in Bulk and Pharmaceutical Dosage Forms; PharmaTutor; 2017; 5(6);29-34
[ABSTRACT WITH CITATION] [VIEW AS HTML]

REFERENCES:
1. The Merck index; An Encyclopedia of Chemical; Drugs and Biologicals; Merck Research Laboratories; Division of Merck & Co Inc; White house Station NJ; 2001,Edn13. 1032
2. Martindale; The extra pharmacopoeia; Royal Pharmaceutical society of Great Britain; 1Lambeth High street London SE17 Jn England; 1996, Vol 31; 435–436.
3. British Pharmacopoeia; The Stationary office under license from the controller of Her Majesty’s stationary office for the department of health on behalf of the health Ministers; 2003, 1595.
4. Indian Pharmacopoeia; Ministry of health and family welfare, Government of India, New Delhi; 2011, Vol 2;1012-1013, 1510-1511.
5. Nafisa Y, Raju K.V and Sindu J., Development and Validation of UV-Spectrophotometric Method for Simultaneous Estimation of Meclizine Hydrochloride. World Journal of Pharmacy and Pharmaceutical Research, 2014, 3(10), 450-457.
6. Kumar M.S, Bairam R and Mahesh P., Formulation and Evaluation of Oral Disintegrating Release Dosage Form containing Meclizine HCl. International Journal of Pharmacy, 2012, 2(4), 717-26.
7. Hamid M.Y and Omera H.A., Spectrophotometric Micro Determination of Meclizine HCl in their Pharmaceutical Formulations and Spiked Plasma. World Journal of Pharmacy, 2014, 3(6), 102-112.
8.Reddy S, Karthik K.P and Kumar V., Simultaneous Estimation of Meclizine HCl and Nicotinic acid in Pharmaceutical Dosage Form by RP-HPLC Method. Applied Journal of Pharmaceutical Research, 2010, 5(2), 73-80.
9. Bari S.B and Kaskhedikar S.G., Simultaneous estimation of meclizine hydrochloride and caffeine in solid dosage form by employing multicomponent and derivative spectrophotometry. Indian Drugs, 1997, 2(34), 85–88.
10. Shinde S.A, Sayyed Z.M, Chaudhari B.P, Chaware V.J and Biyani K.R., Development and Validation of Spectrophotometric Method for Simultaneous Estimation of Meclizine Hydrochloride and Pyridoxine Hydrochloride in Tablet Dosage Form. Journal of Pharm Sci Bioscientific Res, 2016, 6(1), 137-143.
11. Throat D.B, Kalyani Pawar and Paunekar Ashwini., Method development and validation of folic acid by uv-visible spectroscopy. IJPSR, 2015, 6(7), 3088-3090.
12. Abera-Sturi FJ, Jime AI, Arias JJ and Jime F., Simultaneous spectrophotometric determination of folic acid, pyridoxine, riboflaavin, and thiamine by partial least-squares regression. Anal Lett 2002, 35(1), 1677-1691.
13. Rucha K. Patel, Nilam M. Patel, Samir K and Shah.,Development and validation of analytical methods for simultaneous estimation of ferrous ascorbate and folic acid in their combined dosage form.AsianJ.Pharm.Ana,2015,5(3),126-132.
14. Shivani K, Tulja G and Rani., Method development and validation for simultaneous estimation of atorvastatin, fenofibrate and folic acid in pharmaceutical dosage form. Int.J.Pharm Drug Anal, 2015,3 (4),140-149.
15. Pathak A and Rajput S.J., Simultaneous derivative spectrophotometric analysis of doxylamine succinate, pyridoxine hydrochloride and folic acid in combined dosage forms. Indian J Pharm Sci, 2008, 70(4), 513–517.
16.Sreeram V, Basaveswara Rao M.V and Srinivasa rao karumuri., A validated ultra high pressure liquid chromatographic method for qualification and quantification of folic acid in pharmaceutical preparations. International Journal of Chemical Studies, 2013,1(1), 17-27.