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Rameshwaram Institute Of Technology and Management


A REVIEW ON CHEMICAL AND BIOLOGICAL ACTIVITY OF TRIFOLIUM PRATENSE

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About Authors:
1
Neeta Chaudhary, 2Dr. Shalini Tripathi

1
Research student of Rameshwaram Institute of Technology and Management, Sitapur Road, Lucknow (U.P.)
2
Professor of Rameshwaram Institute of Technology and Management, Sitapur Road,
Lucknow (U.P.)
neetakhanna70@gmail.com

Abstract
Trifolium pratense L. is  commonly known as red clover. Red clover acting as a diuretic, expectorant and improving circulation. Trifolium pratenseisoflavones, plant based chemicals that have shown potential in the treatment of a number of conditions associated with menopause, such as hot flashes, cardiovascular health, and osteoporosis. Literature review revealed different pharmacological activities of Trifolium pratense like Biological estimation of oestrogenic activity An  ovariectomized rat model to determine the estrogenic and antiestrogenic activity, Antioxidant Profile, isoflavone biochanin A inhibits aromatase activity and expression, phase IIclinical extract possesses opiate activity, Determination in vivo and in vitro anti-inflammatory activity of red clover.


A REVIEW ON PHARMACOGNOSY, PRE-PHYTOCHEMISTRY AND PHARMACOLOGICAL ANALYSIS OF TRIDAX PROCUMBENS

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ABOUT AUTHORS:
*Amita Pandey1, Dr. Shalini Tripathi2
1Research scholar, Rameshwaram Institute of Technology and Management, Sitapur Road, Lucknow (U.P.)
2Professor, Rameshwaram Institute of Technology and Management, Sitapur Road, Lucknow (U.P.)
*pandey.amita2012@gmail.com

ABSTRACT
Pharmacognostical parameters for the leaves of Tridax procumbens L were studied with the aim of drawing the pharmacopoeial standards for this species. Macroscopical and microscopical characters, pre-phytochemical and pharmacological Studies. The determination of these characters will aid future investigators in their Pharmacological analyses of this species. The Pre-phytochemical screening revealed the presence of alkaloids, carotenoids, flavonoids (catechins and flavones), fumaric acid, fl-sitosterol, saponins and tannins. It is richly endowed with carotenoids, saponins, oleanolic acid and ions like sodium, potassium and calcium. Luteolin, glucoluteolin, quercetin and isoquercetin have been reported from its flowers. It has known for its number of pharmacological activities like hepatoprotective activity, antiinflammatory, wound healing, antidiabetic activity, hypotensive effect, immunomodulating property, bronchial catarrh, dysentery, diarrhoea and to prevent falling of hair promotes the growth of hair, and antimicrobial activity against both gram-positive and gram-negative bacteria. The leaf juice possesses antiseptic, insecticidal and parasiticidal properties, as a remedy against conjunctivitis and is used also to check haemorrhage from cuts, bruises and wounds insect repellent. It is also used as bioadsorbent for chromium (VI). This review focus on folk occurrence and the wide pharmacological activities of Tridax procumbens.


A REVIEW ON ETHNOPHARMACOLOGICAL POTENTIAL OF RICINUS COMMUNIS LINN.

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About Authors:
KM. Preeti*, Ansu Bala Verma
Department of Pharmacology, Rameshwaram institute of technology and management,
Lucknow- 227202,  India
preeti30sept@gmail.com

ABSTRACT
In recent years, Ricinus communis Linn. has become a subject of interest because of its beneficial effects on human health. The present ethnopharmacological review was conducted to evaluate the therapeutic properties of  Ricinus communis by scientific evidences. It belongs to the family Euphobiaceae, which is commonly known as castor. Ricinus communis is found thoughout the hotter parts of India. This plant is extensively used in Ayurveda, Unani, Siddha, Homeopathic and Allopathic system of medicine as cathartic. Traditionally  this plant is used as laxative, purgative, fertilizer and fungicides etc. whereas the plant possess beneficial effects as antioxidant, antifertility, anti-inflammatory, antimicrobial, CNS stimulant, antidiabetic, insecticidal, larvicidal, antinociceptive, antiasthmatic, antiulcer, immunomodulatory, hepatoprotective, lipolytic, wound healing and central analgesic and many other medicinal properties. The extracts or the isolated compounds of this plant have been found to have potent activity against various ailments. The aim of present article is to explore the pharmacological or medicinal importance of the plant Ricinus communis linn.


DENDRIMER : FOR NOVEL DRUG DELIVERY SYSTEM- A REVIEW ARTICLE

About Author:
Deepa yadav
M.Pharm
Rameshwaram institute of Technology and management, Lucknow
deepa.yadav.amethi@gmail.com

ABSTRACT:
Dendrimers have emerged as one of the most interesting themes for researchers as a result of unique functional architecture and macromolecular characteristics dendrimer, have attracted great attention in terms of biomedical  applications. Although the PAMAMdendrimer has already been tested as a carrier for drugs and genes and as a contrast agent for bioimaging . This mini review highlights issues associated with the use of dendrimers as drug delivery vehicles. This article provides an insight into the structure, synthesis, properties,types and the applications of dendrimers in the bio-medical field.


LIPOSOME NOVEL DRUG DELIVERY SYSTEM

About Authors:
Dr.Pushpendra Kumar Tripathi
(director of RITM(pharmacy), *Shipra srivastava
Rameshwaram  Institute Of Technology And Management
Lucknow.
*shipra.hanny1987@gmail.com

Abstract:
The goal of any drug delivery system is spatial placement and temporal delivery of the medicament. Research works are going on to prepare an ideal drug delivery system which satisfies these needs. Researches carried out by ALEC BINGHAM lead to the development of a new drug delivery system called as liposome. Liposomes are small vesicles (_100 nm) composed of various of lipid molecules which build their membrane bilayers. These formulations are mainly composed of phosphatidylcholine (PC) and other constituents such as cholesterol and lipid-conjugated hydrophilic polymers . Liposomes are biodegradable and biocompatible in nature.