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USE OF PYRETHRIN/ PYRETHRUM AND ITS EFFECT ON ENVIRONMENT AND HUMAN: A REVIEW

About Authors:
Vishal Soni*, Amruta Anjikar

CSIR-National Environmental Engineering Research Institute (NEERI),
Nagpur, Maharashtra
vishalsoni8912@yahoo.com

Abstract:
Pyrethrins and pyrethrum are the most frequently used home and garden insecticides in the India. They are often used in indoor sprays, pet shampoos, and aerosol bombs to kill flying and jumping insects. Pyrethrins are a common cause of insecticide poisonings. According to Ministry of Environment and Forest survey of poison control centers, they cause more insecticide poisoning incidents than any other class of insecticides except the organophosphates. Symptoms include headaches, dizziness, and difficulty breathing. Pyrethrins can trigger life-threatening allergic responses including heart failure and severe asthma. In laboratory animals exposed through eating, by injection, or through breathing, pyrethrins have caused anemia. Experiments with dairy cows suggest that nursing mothers exposed to pyrethrins can pass them on to their children. Pyrethrins disrupt the normal functioning of sex hormones. They inhibit binding of sex hormones to human genital skin and proteins in human blood. Pyrethrins are classified as “likely to be human carcinogens” by Environmental Protection Agency (EPA) because they cause thyroid tumors in laboratory tests. Farmers who use pyrethrins have an increased risk of developing leukemia. Pyrethrins are extremely toxic to bees, fish, and other aquatic animals. Following indoor treatments, pyrethrins have persisted up to 2 1/2 months in carpet dust.


Global Institute of Regulatory Affairs provides Industry Oriented Courses in Regulatory Affairs (RA), Quality Assurance & Quality Control (QA/QC) for Life Science Graduates with Placement Assisstance in Pharma Sector

Global Institute of Regulatory Affairs (GIRA) is a change that will help you begin & grow your career in Pharma Industry. GIRA through its industrial expertise offers quality educational programs in the field of Regulatory Affairs and QA/QC. It offers Full time, Part time and Distance Learning courses; this flexibility ensures prior commitments are taken care of and at the same time skills are added to their CVs.

Certifications: GIRA is an ISO Certified Institute as per the norms of ISO 9001:2008. It is Accredited by Joint Accreditation System of Australia & New Zealand (JAS-ANZ).

Distance Learning Courses Offered by GIRA:
* Post Graduate Program in Regulatory Affairs (PGDRA- 10 months)
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Note: Fast Track mode also available for the above given courses.

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Candidates Pursuing Courses from GIRA are associated with:
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REGULATORY AFFAIR: LINK BETWEEN COMPANY AND GOVERNMENT AUTHORITY

About Author:
Yogeshkumar B. Viradiya
Department of Regulatory Affairs, Institute of Management Sciences and Research (IMSR),
Nagpur, Maharashtra.  
viradiya2210@gmail.com

Abstract:
Regulatory affair is the very important department in Pharmaceutical Company. For the protection of public health, government of various countries have developed the regulation for pharmaceutical, cosmetic product, pesticides, veterinary medicines, medical device, agrochemical and complementary medicines by controlling the safety and efficacy of product. Regulatory affair department prepare the registration document which submits to the regulatory agency of various countries for approval of new drug which contain the all important information about new drug. It is called the drug master file of Common technical document (CTD). Regulatory affair is the link between company and government authority. Regulatory affair is important for Product management, Clinical trial, Research & Development. Regulatory personnel have to maintain contact with other specialist like chemist, doctors, veterinarians, engineers, pharmacologist, toxicologist, pharmacists, and accountant. Regulatory authorities of different countries prepare their separate rules and regulation. Main aim of regulatory affair department is to provide safe and effective medicine to people of different companies. Separate rules and regulation in different countries which must be followed by all pharmaceutical company in all over the world.


Work as Institutional manager (Nagpur Headquarter– 2 posts) in Naticon research labs

Naticon research labs were established in 1999. It was registered as a private limited company in the year 2003. We are into manufacturing of pharmaceutical & unique herbal preparations. Business of 25 crore per year. We are the first in India to launch a prebiotic & probiotic vegetarian capsule. Recently we launched a research backed herbal preparation for pih, low foetal wt. Inadequateamneotic fluid. We will soon be launching a herbal product for regenuation of uterus after d & c. We are exporting our products to ciscontries.
1. Pharma company with special enzyme preparations of bromelain, trypsin, rutin, papain,2. Veg capsules probiotics, veg capsules prebiotics,3. Iron with stool softners. Herbal products for pregnancy induced hypertension, low foetal weight, low amneotic fluid.

Post: Institutional manager (Nagpur Headquarter– 2 posts)


Recruitment for Regional Sales Manager @ Naticon Research Labs

Naticon research labs were established in 1999. It was registered as a private limited company in the year 2003. We are into manufacturing of pharmaceutical & unique herbal preparations. Business of 25 crore per year. We are the first in India to launch a prebiotic & probiotic vegetarian capsule. Recently we launched a research backed herbal preparation for pih, low foetal wt. Inadequateamneotic fluid. We will soon be launching a herbal product for regenuation of uterus after d & c. We are exporting our products to ciscontries.
1. Pharma company with special enzyme preparations of bromelain, trypsin, rutin, papain,2. Veg capsules probiotics, veg capsules prebiotics,3. Iron with stool softners. Herbal products for pregnancy induced hypertension, low foetal weight, low amneotic fluid.

Post: Regional Sales Manager


Admission open in world class university for M.Pharm, B.Pharm, MBA & Ph.D - Apeejay Stya University


Carrying forth the Apeejay Stya legacy of over 45 years of excellence in education

School of Pharmaceutical Sciences

Experience the International Edge...
· Established on the academic pattern of the lvy League universities of the USA
· Trans-disciplinary and Liberal Arts approach
· Strong industry linkages to facilitate training & placement
· Truly global campus with students from over 15 countries

Awards & Accolades
· Best Innovation by Private University at World Education Summit 2012
· No.1 in  Innovative Teaching Techniques & No. 3 in Most Reputed Faculty as per TOI B-School Ratings 2013 (North Region)
· Mr. Aditya Berlia, Co-Founder & Pro-Chancellor, Apeejay Stya University, received the 'Outstanding Educational Entrepreneur' award at the World Education Congress Global Awards 2013.
· ASU has been conferred the 'CSR Excellence in Education Award 2013' by Competition Success Review (CSR) magazine in recognition of exceptional contribution made by institutions in their respective areas like education, scientific research, etc.
· E-Gov. Campus of Gurgaon District, Haryana (India) by the Ministry of Communications & Information Technology, in collaboration with the United Nations
· Best Engineering Institute in North India at National Education Awards 2013 by ET Now

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Inviting B.Pharm, M.Pharm, MBA as Assistant Product Executive @ Naticon Research Labs

Naticon research labs were established in 1999. It was registered as a private limited company in the year 2003. We are into manufacturing of pharmaceutical & unique herbal preparations. Business of 25 crore per year. We are the first in India to launch a prebiotic & probiotic vegetarian capsule. Recently we launched a research backed herbal preparation for pih, low foetal wt. Inadequate amneotic fluid. We will soon be launching a herbal product for regenuation of uterus after d & c. We are exporting our products to ciscontries.
1. Pharma company with special enzyme preparations of bromelain, trypsin, rutin, papain, 2. Veg capsules probiotics, veg capsules prebiotics, 3. Iron with stool softners. Herbal products for pregnancy induced hypertension, low foetal weight, low amneotic fluid.

Post: Assistant Product Executive


Admission Noification in Jawaharlal Nehru University

The bill for the establishment of Jawaharlal Nehru University was placed in the Rajya Sabha on September 1, 1965 by the then Education Minister, Mr M.C. Chagla. During the discussion that followed, Hon. M.P. Mr. Bhushan Gupta voiced the opinion that this should not be yet another university. New faculties should be created, including scientific socialism, and one thing that this university should ensure was to keep noble ideas in mind and provide accessibility to students from weaker sections of society.


Joint CSIR-UGC test For Junior Research Fellowship and Eligibility for Lectureship

The CSIR and UGC provide CSIR/UGC Research Fellowship to bright young men and women for training in methods of research under expert guidance of faculty members/scientists working in University Departments/ National Laboratories and Institutions in various fields of Science & Technology. The CSIR/UGC fellowships are tenable in Universities/IITs/Post Graduate Colleges/Govt. Research Establishments including those of the CSIR, Academy of Scientific & Innovative Research (AcSIR), Research & Development establishments of recognized public or private sector industrial firms and other recognized institutions. However, CSIR reserves right to determine the place best suited to provide necessary facilities in the area of science and technology in which the awardees are to specialize. The CSIR/UGC Fellowship is tenable in India. Only bonafide Indian citizen residing in India are eligible for the award of Junior Research fellowships. The program is aimed at National Science & Technology Human Resource Development.

Post: Junior Research Fellowship And Eligibility for Lectureship


Application are invited for Project Assistant Level – III (non-Ph.D) in CSIR-NEERI

Applications are invited for empanelment of Project Assistants/Associate at various levels under the externally funded/sponsored project(s) and CSIR funded Network and other Projects of 12th Five Year Plan in CSIR-NEERI. Area wise panels will be prepared in the following areas / disciplines to accommodate in various Projects as per the needs of the Projects:-
1) Physical Sciences 2) Chemical Sciences 3) Life Sciences 4) Socio–Economics 5) Engineering
As per guidelines details of requirements like qualification, age, stipend etc. are given below:

Post: Project Assistant Level – III (non-Ph.D)