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BIT Group of Institutions invites Directors, Professors, Associate Professors, Assistant Professors for Pharmacy

BIT was established in the year 2001 to spread knowledge in the fields of Engineering &Technology, Pharmacy and management Education by a group of illustrious entrepreneurs under the name Space Age Research and Technology Foundation Charitable Trust. BIT Group of Institutions having four Schools stands amongst the renowned Management and Technical Education Centre imparting courses catering to the needs of industry and providing contribution in the field of consultancy and research.

Post: Directors, Professors, Associate Professors, Assistant Professors


Walk in interview for D.Pharm/ B.Pharm as Pharmacist in HLL Lifecare

HLL Lifecare Limited is a Mini Ratna Company of Govt. of India under the Ministry of Health & Family Welfare. HLL, a schedule B Public Sector Enterprise is today a multi product, multi unit organization addressing various public health challenges. The company with five manufacturing units and marketing offices throughout the country is engaged in the manufacturing and marketing of a wide range of contraceptives and healthcare products.


Opportunity to work as Assistant Drugs Inspector in Staff Selection Commission - Govt of India | 31 vacancies

The Staff Selection Commission is functioning under the Department of Personnel & Training, Government of India. Initially known as Subordinate Services Commission, it was set up on 1 July 1976 primarily to make recruitment on zonal basis for non-technical Group C posts under the Central Government, except the post for which recruitment was made by Railway Service Commission and the industrial establishments. The functions of the Staff Selection Commission have been enlarged from time to time and now it carries out the recruitment for Group B posts also under the Central Government.


Opportunity for Senior Research Fellow in CCRH - 2 Posts | Pharmacognosy/Botany, Chemistry

The Central Council for Research in Homoeopathy (CCRH), New Delhi, an autonomous body of Department of AYUSH, Ministry of Health & Family Welfare, Govt. of India intends to engage the following categories of personnel. The persons selected will be liable for posting in its peripherals Institutes/Units located through out the country. The engagement will be purely on contract basis and selection will be made through Walk-in-Interview:

Post:  Senior Research Fellow- Botany, Chemistry- 2 Posts


Multiple Vacancies in Staff Selection Commission | Technician, Research Assistant, Senior Research Assistant, Botanical Assistant, TAXIDERMIST GRADE -III, Zoo-Ranger, SCIENTIFIC ASSISTANT-I - 28 posts

The Staff Selection Commission is functioning under the Department of Personnel & Training, Government of India. Initially known as Subordinate Services Commission, it was set up on 1 July 1976 primarily to make recruitment on zonal basis for non-technical Group C posts under the Central Government, except the post for which recruitment was made by Railway Service Commission and the industrial establishments.


FORMULATION DEVELOPMENT AND EVALUATION OF LANSOPRAZOLE DR ODT

About Authors:
Mr. Rajat Kumar Pandeya
M. Pharm., Dept. of Pharmaceutics,
Noida Institute of Engg. & Technology
Greater Noida, India.
rajatkumar.pandeya@gmail.com

ABSTRACT :
Oral disintegrating tablets (ODTs) have received ever-increasing demand during the last decade, and the field has become a rapidly growing area in the pharmaceutical industry. Upon introduction into the mouth, these tablets dissolve or disintegrate in the mouth in the absence of additional water for easy administration of active pharmaceutical ingredients. The popularity and usefulness of the formulation resulted in development of several ODT technologies. This review describes various formulations and technologies developed to achieve fast dissolution/dispersion of tablets in the oral cavity. In particular, this review describes in detail FDT technologies based on lyophilization, molding, sublimation, and compaction, as well as approaches to enhancing the ODT properties, such as spraydrying, moisture treatment, sintering, and use of sugar-based disintegrants. In addition, taste-masking technologies, experimental measurements of disintegration times, and clinical studies are also discussed.


PREPARATION AND EVALUATION OF BIODEGRADABLE ALBUMIN MICROSPHERES OF DICLOFENAC SODIUM

About Authors:
Renu1*, Shashi Kant2*, Rajendra Yadav3, Amit Kumar Tyagi4
1Faculty of Pharmacy, Shivdan Singh Institute of Technology and Management, Aligarh (U.P)
2Jubilant Chemsys Ltd, Noida,
3Department of Pharmaceutical Sciences, Gurukul Kangri University Haridwar, 
4Department of Chemistry, Meerut College, Meerut (U.P)
*shashi.pharma83@gmail.com

ABSTRACT :
Diclofenac is currently the eighth largest-selling drug and the most frequently used NSAID (Non-steroidal anti-inflammatory drug) in the world, since its introduction in Japan in 1974. Diclofenac is among the better tolerated NSAIDs. Only major adverse effect of Diclofenac is that it causes direct and indirect irritation of the gastrointestinal tract (GIT). To reduce the side effects on gastrointestinal tract (GIT) and to improve therapeutic efficacy of Diclofenac, it can be formulated in polymeric microspheres.
The use of polymeric carriers in formulations of therapeutic drug delivery systems has gained widespread application, due to their advantage of being biodegradable and biocompatible. Among the microparticulate systems, microspheres have a special importance since it is possible to target drugs and provide controlled release. Diclofenac sodium (DS), is a potent drug in the NSAID group having non-steroidal, anti-inflammatory properties, and is widely used in the treatment of rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. In this present study, it was aimed to prepare microsphere formulations of DS using a natural biodegradable polymer as a carrier for administration to extend the duration period of the dosage form. Microsphere formulations of DS which were prepared were evaluated in vitro for particle size, yield value, encapsulation efficiency, surface morphology, and in vitro drug release.


MOLECULAR CHARACTERIZATION OF A BEGOMOVIRUS ASSOCIATED WITH CLERODENDRON INERME

About Authors:
Sanjay Kumar Yadav*1, Anjana Yadav1, Shahana Majumder2
*1Dept of Pharmaceutical Chemistry, B.B.S. Institute of Pharmaceutical & Allied Sciences, Greater Noida, (U.P.), India
1Dept of Biotechnology, Chhatrapati Sahu Ji Maharaj University, Kanpur, (U.P.), India
2Dept of Biotechnology, Sharda University, School of Engineering and Technology,
Greater Noida, (U.P.), India
*sanjay_yadav3333@yahoo.co.in

ABSTRACT
Viruses are pathogens with an extremely narrow host range. Their phylogenetic origin is vague, tough it has always been considered that viruses are genes that became vagrant after having excluded themselves of the host’s or a related species’ genome (Anderson et.al., 2004). Viruses are usually units consisting of nucleic acids and coat proteins called capsids. Viroids consist only of RNA, i.e. they contain no protein at all. Except for a few cases, Viruses have no energy metabolism of their own. Consequently, they cannot perform syntheses and are thus unable to replicate themselves. Depending on their host species, it is distinguished between plant viruses multiplying almost exclusively within plant cells, bacterial viruses (bacteriophages) that depend on living bacteria, and animal viruses. The genetic information of viruses is either encoded by single-stranded RNA (Most plant viruses), double-stranded RNA (Wound tumor viruses), single-stranded DNA (Gemini viruses) or double stranded DNA (Cauliflower mosaic virus). Based on the shape of the viruses particle, it is distinguished between rod shaped and icosahedral viruses with a capsid that seem almost spherical. Viruses’ cause many disease in humans of international importance for example  smallpox polio, hepatitis etc. viruses cause also many important plant disease and are responsible for huge loss in crop production and quality in all part of the world. Around 25 years ago, when genomic properties of geminiviruses were studied, many scientists regarded them as ‘friends of humans’, because of their  potential as gene transfer vectors in plant genetic engineering and non-harmful effects on host plants. But far from being friends, these viruses have now emerged as foes and are a serious threat to world agriculture now. Increase in international commodity trade, intercontinental transportation networks and a changing global climate have contribute to the spread of this virus and its whitefly vector (Moffat et.al.,1999).