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Olefia Biopharma Limited is one of most dynamic organizations, involved in manufacturing pharmaceutical formulations marketing its products in India as well as worldwide. Olefia has been pursuing its primary mission to provide quality healthcare to ailing millions across the globe at an affordable cost. “Where there is will there is way” is the ground principle for us and based on this principle. Olefia is working today as diverse company of the future. We can make a difference by taking up a cause that we are passionate about.
New Horizons in Pharmacy Education @ Apeejay Stya University, Gurgaon | Admissions open for M.Pharm, Ph.D, MBA
The School of Pharmaceutical Sciences, Apeejay Stya University offers highly advanced and internationally aligned post-graduate courses in Pharmacy Education. The following courses are on offer:
Work as PROFESSIONAL SERVICE REPRESENTATIVES, AREA MANAGER in Karnataka Antibiotics & Pharmaceuticals Ltd.
Karnataka Antibiotics & Pharmaceuticals Ltd., (KAPL) Bangalore is a Government Enterprise. From a modest beginning in 1984, KAPL has grown from strength to strength in the areas of manufacturing and marketing of various life saving and essential drugs. With an ISO accredition from KPMG, Netherlands, KAPL is recognised for its total commitment to quality and services in domestic and international markets. On profit from inception, KAPL facilities are approved by many international clients.
We are an established Pharmaceutical Company having a committed team of 825 professionals across the country. Having created a position for ourselves among Top 35 Pharmaceutical Companies prescription wise, we are further strengthening our presence in potential specialty areas -Cardiovascular and Anti-Diabetic Segments. For our expansion programme we require:
Post: Zonal Sales Manager, Regional Sales Manager
*1Akanksha baranwal, 2Akanksha Sharma, 3Anamika singh
1,3Department of pharmacology
2Department of clinical research
Noida Institute of Engineering and Technology
The purpose of this review is to provide a basic understanding of the important relationship between microvascular remodelling, angiogenesis and hypertension, that is, provide an overview of recent experimental and clinical evidence from anti-hypertensive and pro- and anti-angiogenic therapy with respect to hypertension and microvascular structure. Microvascular rarefaction, that is, a loss of terminal arterioles and capillaries, is found in most forms of human and experimental arterial hypertension. This further increases peripheral resistance, and aggravates hypertension and hypertension-induced target organ damage. In some cases with a genetic predisposition, hypertension is preceded by a loss of microvessels. Therefore, new therapies aimed at reversing microvascular rarefaction potentially represent candidate treatments of hypertension. The microvasculature is formed by the continuous balance between de novo angiogenesis and microvascular regression. Imbalanced angiogenesis, in addition to functional shut-off of blood flow, contributes to microvascular rarefaction. Numerous clinical trials assessing anti-angiogenic agents in cancer patients show that this therapy leads to microvascular rarefaction and causes or aggravates hypertension. The development of specific pro-angiogenic treatment to correct hypertension or ischaemic disorders, however, it is still in its infancy. On the other hand, long-term treatment by classic anti-hypertensive therapies that present vasodilator activity can correct for hypertension-associated rarefaction in man.
The National Institute of Biologicals, an autonomous Institute under the Ministry of Health & Family Welfare, Government of India, is a premier Scientific Organization and a Centre of Excellence to ensure quality of vaccines and biologicals in the country.
Applications are invited for the following posts on direct recruitment basis:
Post: Jr. Scientist
Anamika singh*1, Neha Singh2
1M.Pharm (Department of Pharmacology)
2M.Pharm (Department of Pharmaceutics)
Noida Institute of Engineering and Technology.
Tuberculosis is a leading killer of young adults worldwide and the global scourge of multi-drug resistant tuberculosis is reaching epidemic proportions. It is endemic in most developing countries and resurgent in developed and developing countries with high rates of human immunodeficiency virus infection. This article reviews the current situation in terms of drug delivery approaches for tuberculosis chemotherapy. A number of novel implant-, microparticulate-, and various other carrier-based drug delivery systems incorporating the principal anti-tuberculosis agents have been fabricated that either target the site of tuberculosis infection or reduce the dosing frequency with the aim of improving patient outcomes. These developments in drug delivery represent attractive options with significant merit, however, there is a requisite to manufacture an oral system, which directly addresses issues of unacceptable rifampicin bioavailability in fixed-dose combinations. This is fostered by the need to deliver medications to patients more efficiently and with fewer side effects, especially in developing countries. The fabrication of a polymeric once-daily oral multiparticulate fixed-dose combination of the principal anti-tuberculosis drugs, which attains segregated delivery of rifampicin and isoniazid for improved rifampicin bioavailability, could be a step in the right direction in addressing issues of treatment failure due to patient non-compliance.
Department of pharmaceutical chemistry
Noida Institute Of Engineering & Technology, Noida
The antioxidative activity of a total of 92 phenolic extracts from edible and nonedible plant materials (berries, fruits, vegetables, herbs, cereals, tree materials, plant sprouts, and seeds) was examined by autoxidation of methyl linoleate. The content of total phenolics in the extracts was determined spectrometrically according to the Folin-Ciocalteu procedure and calculated as gallic acid equivalents (GAE). Among edible plant materials, remarkable high antioxidant activity and high total phenolic content (GAE > 20 mg/g) were found in berries, especially aronia and crowberry. Apple extracts (two varieties) showed also strong antioxidant activity even though the total phenolic contents were low (GAE < 12.1 mg/g). Among nonedible plant materials, high activities were found in tree materials, especially in willow bark, spruce needles, pine bark and cork, and birch phloem, and in some medicinal plants including heather, bog-rosemary, willow herb, and meadowsweet. In addition, potato peel and beetroot peel extracts showed strong antioxidant effects. To utilize these significant sources of natural antioxidants, further characterization of the phenolic composition is needed.
Applications are invited up to 19-07-2013 for one post of Scientist-C (Cytogenetics/ Molecular Genetics) at the Institute of Cytology & Preventive Oncology, Noida. in the Pay Band PB-3 of Rs.15600–39100 + Grade Pay Rs.6600/- and usual allowances as admissible as per Government norms.
Post: Scientist-C (Cytogenetics/Molecular Genetics)
Vishwa Deepak Kumar*, Abhishek Sharma, Rajneesh Mishra, Kanchan Sharma
B.Pharmacy, 2nd year
Department of Pharmacy, IEC group of institutions,
Greater Noida (U.P) INDIA, Pin- 201301
For the past few decades, there has been a considerable research interest in the area of drug delivery using particulate delivery systems as carriers for small and large molecules. Particulate systems like nanoparticles have been used as a physical approach to alter and improve the pharmacokinetic and pharmacodynamic properties of various types of drug molecules. They have been used in vivo to protect the drug entity in the systemic circulation; various polymers have been used in the formulation of nanoparticles for drug delivery research to increase therapeutic benefit, while minimizing side effects. Here, we review various aspects of nanoparticle formulation, characterization, effect of their characteristics and their applications in delivery of drug molecules and therapeutic genes. Nanoparticles are the preparations having size in nanometers.