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Vishwa Deepak Kumar*, Abhishek Sharma, Rajneesh Mishra, Kanchan Sharma
B.Pharmacy, 2nd year
Department of Pharmacy, IEC group of institutions,
Greater Noida (U.P) INDIA, Pin- 201301
For the past few decades, there has been a considerable research interest in the area of drug delivery using particulate delivery systems as carriers for small and large molecules. Particulate systems like nanoparticles have been used as a physical approach to alter and improve the pharmacokinetic and pharmacodynamic properties of various types of drug molecules. They have been used in vivo to protect the drug entity in the systemic circulation; various polymers have been used in the formulation of nanoparticles for drug delivery research to increase therapeutic benefit, while minimizing side effects. Here, we review various aspects of nanoparticle formulation, characterization, effect of their characteristics and their applications in delivery of drug molecules and therapeutic genes. Nanoparticles are the preparations having size in nanometers.
United Institute of Pharmacy invites Principal/Director, Professors, Associate Professors, Assistant Professors
The United Group, founded by late Shri Shiv Ram Das Gulati in 1951 emerged from a transport business to the giants in the fields of education, services, transportation and journalism. The group made a mammoth leap in the education arena in the mid 80s by being the pioneers in computer education. This further lead to the establishment of United Institute of Management and United College of Engineering & Research in Allahabad.
Post: Principal/Director, Professors, Associate Professors, Assistant Professors
M.Pharm ( department of pharmaceutics)
Noida institute of engineering and technology.
Swine flu has been creating a terror effects all round the globe and has been declared epidemic in most part of the world. Swine flu refers to swine influenza or the viral infection caused by any of the several types of swine influenza virus. Only people who used to have direct contact with pigs were observed to get swine flu in the past. But, H1N1 virus is a new swine flu virus and it contains the genetic material of swine, bird and human influenza virus. H1N1 is an Influenza A virus. Swine flu can produce a number of symptoms in both adults and children. In India day by day the graph of infected person has been climbed up so, it is important to take into consideration about this disease as it may prove deadly one. The intensity of this disorder can be lowered by diagnosing and taking proper treatments.
Khushbu Singh*1, Chandana Majee2
1 M.Pharm ( department of pharmaceutics)
2 Assistant Professor, department of pharmaceutical chemistry.
Noida institute of engineering and technology, noida
Dendrimers are highly branched and monodisperse macromolecules that display an exact and large number of functional groups distributed with unprecedented control on the dendritic framework. Based on their globular structure, compared to linear polymers of the same molecular weight, dendrimers are foreseen to deliver extraordinary features for applications in areas such as cancer therapy, biosensors for diagnostics and light harvesting scaffolds. Of the large number of reports on dendrimer synthesis only a few have reached commercial availability. This limitation can be traced back to challenges in the synthetic paths including a large number of reaction steps required to obtain dendritic structures with desired features. Along with an increased number of reaction steps come not only increased waste of chemical and valuable starting materials but also an increased probability to introduce structural defects in the dendritic framework.Dendrimer chemistry is one of the most fascinating and rapidly expanding areas of modern chemistry. Nanoparticle drug-delivery systems are the popular ones as are able to increase the selectivity and stability of therapeutic agents. However reticuloendothelial system (RES) uptake, drug leakage, immunogenicity, hemolytic toxicity, cytotoxicity, hydrophobicity restrict the use of these nanostructures. These shortcomings are overcome by surface engineering the dendrimer such as Polyester dendrimer, Citric acid dendrimer, Arginine dendrimer, Glycodendrimers, PEGylated dendrimers, etc. The bioactive agents can be easily encapsulated into the interior of the dendrimers or chemically attached i.e. conjugated or physically adsorbed onto the dendrimer surface, serving the desired properties of the carrier to the specific needs of the active material and its therapeutic applications
Invites applications for Faculty Positions as Professor /Associate Professor/ Assistant Professor @ RKGIT
HLL Lifecare Limited (formerly Hindustan Latex Limited) India’s leading manufacturers and marketers of Contraceptive, Health Care and Pharma products is a Mini Ratna Company under the Ministry of Health & Family Welfare, a Govt. of India Enterprise, with Seven manufacturing units and marketing offices throughout the country.
Opportunity for Director, Professor, Associate Professor, Assistant Professor in IIMT Group of Colleges
The IIMT Group of colleges was founded in the year 1994. Since then the group has grown impressively and achieved exemplary recognition from corporate, academia, and professional circles.
At IIMT we are committed to provide a value driven culture along with creating a professional environment. The IIMT as a group is large and diversified group and imparts knowledge in field of Engineering, Management, Medical Sciences, Hotel Management, Nursing, Education, Law etc. The IIMT group has more than 1330 highly qualified and experienced faculty members in their respective functional areas. IIMT boasts of having more than 20,000 students in various courses in five campuses.
Vishwa Deepak kumar
Departement of Pharmacy,
IEC group of institution,
Greater Noida (U.P), Pin- 201301
Pharmacovigilance is an important and integral part of clinical research. Pharmacovigilance is “defined as the pharmacological science relating to the detection, assessment, understanding and prevention of adverse effects, particularly long term and short term adverse effects of medicines. This addresses what exactly is Pharmacovigilance? What do we know of its benefits and risks, challenges and the future hold for pharmacovigilance in Indian medicine. Here the main focus on the aims and role of Pharmacovigilance in medicines regulation and their Partners. This article describes and discusses the National programme of pharmacovigilance and centre in India. There role in collecting the reports ADRs of medicines. Further effectiveness and risk assessments of therapies are been discussed. The important role played by health care professional, pharmaceutical industries, media, and programmes carried by WHO. Finally the conclusion describes the major challenges and achievements for the future pharmacovigilance programmeand toxicity is not socritical if botanicals are used in traditional forms (Harborne., 1998).
Neha singh*1, Chandana Majee2
1.M.Pharm ( Department of Pharmaceutics)
2.Assistant Professor, Departmrnt of pharmaceutical chemistry.
Noida Institute of Engineering and Technology, Noida
In order to achieve a successful colon targeted drug delivery system, a drug needs to be protected from degradation, release and/or absorption in the upper portion of the gastrointestinal tract (GIT) and then ensure abrupt or controlled release in the proximal colon. Such a system can be formulated by utilizing microbial triggering degradation of polymer coating/ gastro intestinal (GI) transit time (time dependent)/ pH dependent approach etc. But unfortunately it has been found that colonic microflora, GI transit time and pH varies considerably inside a human system by several factors, in addition to this the native biodegradable polysaccharides which are used widely for the microbial triggering colonic drug delivery system (CDDS), are having high aqueous solubility on account of which a single unit colon targeted drug delivery systems may suffer from dose dumping due to overall catastrophic failure of the film around a monolith, which would then release the whole drug, that may lead to drastically compromised systemic drug bioavailability or loss of local therapeutic action in the colon. This review emphasizes some of the causes which make a single unit dosage form unsuitable for targeting to colon by using microbial triggering/GI transit time/pH dependent approach, and at the same time discusses researches which have been carried out to alleviate these problems by utilizing multiparticulate combined approaches.
The Jaypee Group of Companies has consistently displayed full awareness of its social responsibilities through the Jaiprakash Sewa Sansthan (JSS), a ‘not for profit’ Trust. The Group believes that Education is the cornerstone to economic development and which alone can assist build India into a developed nation.
With the thought of using technology and management effectively, thevisionary founder of the JSS, Shri Jaiprakash Gaur set up 3 technical institutes of higher education to host the best of faculty, students and educational infrastructure to ensure creation, generation, dissemination and application of knowledge to mould the world leaders of tomorrow.